Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7X093_LEIDO

TriTrypDb:

LdCL_260032000 , LDHU3_26.3380

Length:

151

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X093

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X093

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	131	133	PF00675	0.572
CLV_NRD_NRD_1	33	35	PF00675	0.509
CLV_NRD_NRD_1	70	72	PF00675	0.544
CLV_NRD_NRD_1	96	98	PF00675	0.683
CLV_PCSK_KEX2_1	131	133	PF00082	0.546
CLV_PCSK_KEX2_1	149	151	PF00082	0.503
CLV_PCSK_KEX2_1	33	35	PF00082	0.466
CLV_PCSK_KEX2_1	70	72	PF00082	0.440
CLV_PCSK_PC1ET2_1	149	151	PF00082	0.717
CLV_PCSK_SKI1_1	18	22	PF00082	0.461
CLV_PCSK_SKI1_1	34	38	PF00082	0.570
CLV_PCSK_SKI1_1	70	74	PF00082	0.425
DOC_PP2B_LxvP_1	19	22	PF13499	0.436
DOC_USP7_MATH_1	119	123	PF00917	0.563
DOC_USP7_UBL2_3	145	149	PF12436	0.615
DOC_USP7_UBL2_3	78	82	PF12436	0.562
DOC_WW_Pin1_4	57	62	PF00397	0.563
LIG_14-3-3_CanoR_1	25	30	PF00244	0.430
LIG_14-3-3_CanoR_1	45	54	PF00244	0.350
LIG_Actin_WH2_2	102	120	PF00022	0.476
LIG_BIR_II_1	1	5	PF00653	0.428
LIG_FHA_1	24	30	PF00498	0.501
LIG_FHA_1	49	55	PF00498	0.542
LIG_SH2_GRB2like	91	94	PF00017	0.553
LIG_SH2_STAP1	91	95	PF00017	0.553
LIG_SH3_3	113	119	PF00018	0.537
LIG_SUMO_SIM_par_1	25	31	PF11976	0.378
LIG_SUMO_SIM_par_1	51	58	PF11976	0.618
LIG_SUMO_SIM_par_1	60	66	PF11976	0.479
LIG_TRAF2_1	28	31	PF00917	0.389
LIG_UBA3_1	72	78	PF00899	0.474
MOD_CK1_1	122	128	PF00069	0.547
MOD_CK1_1	48	54	PF00069	0.554
MOD_CK2_1	25	31	PF00069	0.387
MOD_Cter_Amidation	146	149	PF01082	0.753
MOD_Cter_Amidation	31	34	PF01082	0.447
MOD_GlcNHglycan	124	127	PF01048	0.531
MOD_GlcNHglycan	98	101	PF01048	0.606
MOD_GSK3_1	118	125	PF00069	0.627
MOD_N-GLC_1	66	71	PF02516	0.489
MOD_NEK2_2	124	129	PF00069	0.463
MOD_PKA_2	117	123	PF00069	0.630
MOD_PKA_2	96	102	PF00069	0.535
MOD_Plk_1	48	54	PF00069	0.535
MOD_ProDKin_1	57	63	PF00069	0.558
MOD_SUMO_rev_2	49	59	PF00179	0.571
TRG_DiLeu_BaEn_1	49	54	PF01217	0.613
TRG_DiLeu_BaEn_4	30	36	PF01217	0.426
TRG_DiLeu_LyEn_5	49	54	PF01217	0.464
TRG_ER_diArg_1	131	134	PF00400	0.555
TRG_ER_diArg_1	33	35	PF00400	0.466
TRG_ER_diArg_1	70	72	PF00400	0.476
TRG_ER_diLys_1	148	151	PF00400	0.598

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDC7	Leptomonas seymouri	76%	100%
A0A0S4JH37	Bodo saltans	37%	100%
A0A1X0NEM8	Trypanosomatidae	52%	100%
A0A3R7R8R4	Trypanosoma rangeli	52%	100%
A4HFA2	Leishmania braziliensis	83%	100%
C9ZX03	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	97%
E9AYN9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q8T3	Leishmania major	96%	100%