LeishMANIAdb
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PH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
PH domain-containing protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7X086_LEIDO
TriTrypDb:
LdCL_260031100
Length:
139

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X086
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X086

Putative motif mimicry

Leishmania From To Domain/Motif Score
DOC_CKS1_1 131 136 PF01111 0.421
DOC_CYCLIN_yCln2_LP_2 131 137 PF00134 0.422
DOC_MAPK_gen_1 110 118 PF00069 0.437
DOC_PP1_RVXF_1 23 30 PF00149 0.406
DOC_PP2B_LxvP_1 135 138 PF13499 0.433
DOC_USP7_MATH_1 123 127 PF00917 0.445
DOC_USP7_MATH_1 3 7 PF00917 0.460
DOC_USP7_UBL2_3 55 59 PF12436 0.358
DOC_WW_Pin1_4 116 121 PF00397 0.461
DOC_WW_Pin1_4 130 135 PF00397 0.422
LIG_14-3-3_CanoR_1 113 117 PF00244 0.457
LIG_APCC_ABBAyCdc20_2 71 77 PF00400 0.377
LIG_BIR_II_1 1 5 PF00653 0.478
LIG_FHA_1 81 87 PF00498 0.340
LIG_LIR_Gen_1 103 108 PF02991 0.358
LIG_LIR_Nem_3 103 107 PF02991 0.362
LIG_LIR_Nem_3 45 51 PF02991 0.295
LIG_Pex14_1 33 37 PF04695 0.300
LIG_Pex14_2 29 33 PF04695 0.364
LIG_SH2_STAP1 52 56 PF00017 0.325
LIG_SH2_STAT5 37 40 PF00017 0.275
LIG_SH2_STAT5 48 51 PF00017 0.274
LIG_SH3_3 117 123 PF00018 0.454
LIG_SH3_3 131 137 PF00018 0.422
LIG_SH3_3 60 66 PF00018 0.339
LIG_SUMO_SIM_par_1 80 88 PF11976 0.347
LIG_WRC_WIRS_1 101 106 PF05994 0.355
MOD_CK2_1 116 122 PF00069 0.459
MOD_CK2_1 3 9 PF00069 0.450
MOD_GlcNHglycan 5 8 PF01048 0.447
MOD_GlcNHglycan 97 100 PF01048 0.339
MOD_GSK3_1 112 119 PF00069 0.452
MOD_GSK3_1 25 32 PF00069 0.399
MOD_N-GLC_1 18 23 PF02516 0.333
MOD_NEK2_1 29 34 PF00069 0.356
MOD_NEK2_1 85 90 PF00069 0.340
MOD_NEK2_2 97 102 PF00069 0.341
MOD_PKA_1 25 31 PF00069 0.408
MOD_PKA_2 109 115 PF00069 0.415
MOD_PKA_2 95 101 PF00069 0.345
MOD_Plk_1 18 24 PF00069 0.342
MOD_Plk_1 80 86 PF00069 0.348
MOD_Plk_4 25 31 PF00069 0.408
MOD_Plk_4 80 86 PF00069 0.348
MOD_ProDKin_1 116 122 PF00069 0.459
MOD_ProDKin_1 130 136 PF00069 0.424
TRG_DiLeu_BaEn_1 80 85 PF01217 0.357
TRG_ENDOCYTIC_2 37 40 PF00928 0.275
TRG_ER_diArg_1 33 36 PF00400 0.305
TRG_ER_diArg_1 86 89 PF00400 0.346

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS