Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X067_LEIDO

TriTrypDb:

LdBPK_262370.1 , LdCL_260029400 , LDHU3_26.3090

Length:

861

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X067

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X067

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	265	269	PF00656	0.650
CLV_C14_Caspase3-7	516	520	PF00656	0.838
CLV_C14_Caspase3-7	560	564	PF00656	0.668
CLV_C14_Caspase3-7	592	596	PF00656	0.780
CLV_C14_Caspase3-7	771	775	PF00656	0.796
CLV_C14_Caspase3-7	78	82	PF00656	0.550
CLV_NRD_NRD_1	204	206	PF00675	0.533
CLV_NRD_NRD_1	298	300	PF00675	0.733
CLV_NRD_NRD_1	321	323	PF00675	0.708
CLV_NRD_NRD_1	350	352	PF00675	0.789
CLV_NRD_NRD_1	408	410	PF00675	0.663
CLV_NRD_NRD_1	417	419	PF00675	0.626
CLV_NRD_NRD_1	537	539	PF00675	0.853
CLV_NRD_NRD_1	583	585	PF00675	0.853
CLV_NRD_NRD_1	622	624	PF00675	0.641
CLV_NRD_NRD_1	676	678	PF00675	0.838
CLV_NRD_NRD_1	688	690	PF00675	0.691
CLV_NRD_NRD_1	709	711	PF00675	0.812
CLV_NRD_NRD_1	763	765	PF00675	0.850
CLV_NRD_NRD_1	769	771	PF00675	0.797
CLV_PCSK_FUR_1	348	352	PF00082	0.692
CLV_PCSK_FUR_1	761	765	PF00082	0.792
CLV_PCSK_KEX2_1	204	206	PF00082	0.615
CLV_PCSK_KEX2_1	298	300	PF00082	0.733
CLV_PCSK_KEX2_1	321	323	PF00082	0.708
CLV_PCSK_KEX2_1	350	352	PF00082	0.789
CLV_PCSK_KEX2_1	372	374	PF00082	0.763
CLV_PCSK_KEX2_1	417	419	PF00082	0.678
CLV_PCSK_KEX2_1	537	539	PF00082	0.853
CLV_PCSK_KEX2_1	582	584	PF00082	0.859
CLV_PCSK_KEX2_1	606	608	PF00082	0.780
CLV_PCSK_KEX2_1	671	673	PF00082	0.857
CLV_PCSK_KEX2_1	676	678	PF00082	0.778
CLV_PCSK_KEX2_1	707	709	PF00082	0.846
CLV_PCSK_KEX2_1	763	765	PF00082	0.850
CLV_PCSK_KEX2_1	769	771	PF00082	0.797
CLV_PCSK_PC1ET2_1	372	374	PF00082	0.763
CLV_PCSK_PC1ET2_1	606	608	PF00082	0.780
CLV_PCSK_PC1ET2_1	671	673	PF00082	0.857
CLV_PCSK_PC1ET2_1	707	709	PF00082	0.807
CLV_PCSK_PC7_1	672	678	PF00082	0.818
CLV_PCSK_PC7_1	703	709	PF00082	0.779
CLV_PCSK_SKI1_1	108	112	PF00082	0.534
CLV_PCSK_SKI1_1	153	157	PF00082	0.695
CLV_PCSK_SKI1_1	162	166	PF00082	0.609
CLV_PCSK_SKI1_1	204	208	PF00082	0.722
CLV_PCSK_SKI1_1	584	588	PF00082	0.765
CLV_PCSK_SKI1_1	671	675	PF00082	0.684
CLV_PCSK_SKI1_1	778	782	PF00082	0.663
DEG_APCC_DBOX_1	152	160	PF00400	0.813
DEG_APCC_KENBOX_2	4	8	PF00400	0.656
DEG_COP1_1	41	49	PF00400	0.800
DEG_SCF_FBW7_1	509	516	PF00400	0.754
DEG_SPOP_SBC_1	262	266	PF00917	0.690
DEG_SPOP_SBC_1	611	615	PF00917	0.778
DEG_SPOP_SBC_1	661	665	PF00917	0.754
DOC_ANK_TNKS_1	408	415	PF00023	0.780
DOC_CDC14_PxL_1	731	739	PF14671	0.805
DOC_CDC14_PxL_1	80	88	PF14671	0.580
DOC_CKS1_1	490	495	PF01111	0.820
DOC_CKS1_1	849	854	PF01111	0.814
DOC_CYCLIN_RxL_1	580	588	PF00134	0.778
DOC_CYCLIN_yCln2_LP_2	505	511	PF00134	0.758
DOC_MAPK_HePTP_8	369	384	PF00069	0.670
DOC_PP1_RVXF_1	581	588	PF00149	0.781
DOC_PP2B_LxvP_1	382	385	PF13499	0.726
DOC_PP4_FxxP_1	211	214	PF00568	0.722
DOC_PP4_FxxP_1	283	286	PF00568	0.632
DOC_PP4_FxxP_1	527	530	PF00568	0.835
DOC_PP4_MxPP_1	529	532	PF00568	0.615
DOC_USP7_MATH_1	134	138	PF00917	0.738
DOC_USP7_MATH_1	145	149	PF00917	0.625
DOC_USP7_MATH_1	178	182	PF00917	0.625
DOC_USP7_MATH_1	225	229	PF00917	0.754
DOC_USP7_MATH_1	249	253	PF00917	0.733
DOC_USP7_MATH_1	314	318	PF00917	0.859
DOC_USP7_MATH_1	332	336	PF00917	0.555
DOC_USP7_MATH_1	425	429	PF00917	0.797
DOC_USP7_MATH_1	45	49	PF00917	0.798
DOC_USP7_MATH_1	475	479	PF00917	0.763
DOC_USP7_MATH_1	611	615	PF00917	0.778
DOC_USP7_MATH_1	659	663	PF00917	0.746
DOC_USP7_MATH_1	819	823	PF00917	0.786
DOC_USP7_MATH_2	4	10	PF00917	0.620
DOC_WW_Pin1_4	229	234	PF00397	0.755
DOC_WW_Pin1_4	247	252	PF00397	0.553
DOC_WW_Pin1_4	309	314	PF00397	0.825
DOC_WW_Pin1_4	316	321	PF00397	0.756
DOC_WW_Pin1_4	352	357	PF00397	0.852
DOC_WW_Pin1_4	385	390	PF00397	0.790
DOC_WW_Pin1_4	41	46	PF00397	0.823
DOC_WW_Pin1_4	427	432	PF00397	0.837
DOC_WW_Pin1_4	443	448	PF00397	0.552
DOC_WW_Pin1_4	453	458	PF00397	0.655
DOC_WW_Pin1_4	460	465	PF00397	0.543
DOC_WW_Pin1_4	489	494	PF00397	0.859
DOC_WW_Pin1_4	498	503	PF00397	0.650
DOC_WW_Pin1_4	509	514	PF00397	0.673
DOC_WW_Pin1_4	636	641	PF00397	0.811
DOC_WW_Pin1_4	69	74	PF00397	0.712
DOC_WW_Pin1_4	691	696	PF00397	0.783
DOC_WW_Pin1_4	813	818	PF00397	0.738
DOC_WW_Pin1_4	822	827	PF00397	0.730
DOC_WW_Pin1_4	839	844	PF00397	0.555
DOC_WW_Pin1_4	848	853	PF00397	0.659
LIG_14-3-3_CanoR_1	108	115	PF00244	0.705
LIG_14-3-3_CanoR_1	179	183	PF00244	0.702
LIG_14-3-3_CanoR_1	231	241	PF00244	0.754
LIG_14-3-3_CanoR_1	301	310	PF00244	0.776
LIG_14-3-3_CanoR_1	322	332	PF00244	0.697
LIG_14-3-3_CanoR_1	469	476	PF00244	0.831
LIG_14-3-3_CanoR_1	504	508	PF00244	0.781
LIG_14-3-3_CanoR_1	609	618	PF00244	0.719
LIG_14-3-3_CanoR_1	660	669	PF00244	0.653
LIG_14-3-3_CanoR_1	87	93	PF00244	0.712
LIG_Actin_WH2_2	73	89	PF00022	0.621
LIG_BIR_III_2	81	85	PF00653	0.581
LIG_BRCT_BRCA1_1	101	105	PF00533	0.628
LIG_BRCT_BRCA1_1	433	437	PF00533	0.757
LIG_BRCT_BRCA1_1	545	549	PF00533	0.730
LIG_EVH1_1	527	531	PF00568	0.832
LIG_FHA_1	109	115	PF00498	0.706
LIG_FHA_1	248	254	PF00498	0.788
LIG_FHA_1	256	262	PF00498	0.794
LIG_FHA_1	270	276	PF00498	0.696
LIG_FHA_1	379	385	PF00498	0.660
LIG_FHA_1	428	434	PF00498	0.751
LIG_FHA_1	468	474	PF00498	0.751
LIG_FHA_1	641	647	PF00498	0.770
LIG_FHA_1	686	692	PF00498	0.788
LIG_FHA_2	164	170	PF00498	0.750
LIG_FHA_2	472	478	PF00498	0.759
LIG_FHA_2	514	520	PF00498	0.841
LIG_FHA_2	558	564	PF00498	0.763
LIG_FHA_2	645	651	PF00498	0.780
LIG_FHA_2	755	761	PF00498	0.741
LIG_FHA_2	769	775	PF00498	0.682
LIG_FHA_2	777	783	PF00498	0.736
LIG_FHA_2	832	838	PF00498	0.744
LIG_LIR_Apic_2	305	311	PF02991	0.813
LIG_LIR_Gen_1	300	311	PF02991	0.665
LIG_LIR_Gen_1	566	576	PF02991	0.663
LIG_LIR_Nem_3	300	306	PF02991	0.665
LIG_LIR_Nem_3	715	719	PF02991	0.776
LIG_Pex14_1	856	860	PF04695	0.805
LIG_SH2_CRK	200	204	PF00017	0.672
LIG_SH2_CRK	308	312	PF00017	0.748
LIG_SH2_STAT5	308	311	PF00017	0.748
LIG_SH2_STAT5	391	394	PF00017	0.769
LIG_SH2_STAT5	526	529	PF00017	0.844
LIG_SH3_1	307	313	PF00018	0.745
LIG_SH3_1	350	356	PF00018	0.782
LIG_SH3_1	451	457	PF00018	0.646
LIG_SH3_1	634	640	PF00018	0.662
LIG_SH3_2	311	316	PF14604	0.762
LIG_SH3_3	12	18	PF00018	0.627
LIG_SH3_3	182	188	PF00018	0.690
LIG_SH3_3	235	241	PF00018	0.749
LIG_SH3_3	307	313	PF00018	0.745
LIG_SH3_3	350	356	PF00018	0.696
LIG_SH3_3	451	457	PF00018	0.792
LIG_SH3_3	478	484	PF00018	0.709
LIG_SH3_3	490	496	PF00018	0.788
LIG_SH3_3	525	531	PF00018	0.838
LIG_SH3_3	634	640	PF00018	0.746
LIG_SH3_3	840	846	PF00018	0.757
LIG_SUMO_SIM_anti_2	98	105	PF11976	0.653
LIG_TRAF2_1	520	523	PF00917	0.833
LIG_TRAF2_2	852	857	PF00917	0.813
LIG_WW_3	825	829	PF00397	0.797
MOD_CDC14_SPxK_1	319	322	PF00782	0.722
MOD_CDC14_SPxK_1	501	504	PF00782	0.742
MOD_CDK_SPK_2	316	321	PF00069	0.785
MOD_CDK_SPK_2	848	853	PF00069	0.816
MOD_CDK_SPxK_1	316	322	PF00069	0.723
MOD_CDK_SPxK_1	498	504	PF00069	0.750
MOD_CDK_SPxK_1	822	828	PF00069	0.829
MOD_CDK_SPxxK_3	309	316	PF00069	0.738
MOD_CK1_1	148	154	PF00069	0.700
MOD_CK1_1	22	28	PF00069	0.820
MOD_CK1_1	229	235	PF00069	0.825
MOD_CK1_1	256	262	PF00069	0.780
MOD_CK1_1	326	332	PF00069	0.778
MOD_CK1_1	355	361	PF00069	0.737
MOD_CK1_1	436	442	PF00069	0.835
MOD_CK1_1	456	462	PF00069	0.488
MOD_CK1_1	463	469	PF00069	0.602
MOD_CK1_1	471	477	PF00069	0.639
MOD_CK1_1	489	495	PF00069	0.553
MOD_CK1_1	557	563	PF00069	0.766
MOD_CK1_1	566	572	PF00069	0.651
MOD_CK1_1	574	580	PF00069	0.537
MOD_CK1_1	662	668	PF00069	0.841
MOD_CK1_1	685	691	PF00069	0.649
MOD_CK1_1	822	828	PF00069	0.829
MOD_CK1_1	848	854	PF00069	0.814
MOD_CK2_1	289	295	PF00069	0.680
MOD_CK2_1	392	398	PF00069	0.846
MOD_CK2_1	471	477	PF00069	0.756
MOD_CK2_1	619	625	PF00069	0.813
MOD_CK2_1	691	697	PF00069	0.804
MOD_CK2_1	776	782	PF00069	0.843
MOD_Cter_Amidation	348	351	PF01082	0.791
MOD_DYRK1A_RPxSP_1	316	320	PF00069	0.784
MOD_DYRK1A_RPxSP_1	69	73	PF00069	0.593
MOD_GlcNHglycan	136	139	PF01048	0.756
MOD_GlcNHglycan	141	146	PF01048	0.698
MOD_GlcNHglycan	192	195	PF01048	0.738
MOD_GlcNHglycan	228	231	PF01048	0.806
MOD_GlcNHglycan	26	29	PF01048	0.777
MOD_GlcNHglycan	291	294	PF01048	0.723
MOD_GlcNHglycan	344	347	PF01048	0.741
MOD_GlcNHglycan	465	468	PF01048	0.745
MOD_GlcNHglycan	47	50	PF01048	0.744
MOD_GlcNHglycan	470	473	PF01048	0.687
MOD_GlcNHglycan	477	481	PF01048	0.611
MOD_GlcNHglycan	509	512	PF01048	0.854
MOD_GlcNHglycan	556	559	PF01048	0.837
MOD_GlcNHglycan	576	579	PF01048	0.530
MOD_GlcNHglycan	597	600	PF01048	0.798
MOD_GlcNHglycan	630	633	PF01048	0.863
MOD_GlcNHglycan	684	688	PF01048	0.624
MOD_GlcNHglycan	69	72	PF01048	0.801
MOD_GlcNHglycan	743	746	PF01048	0.783
MOD_GlcNHglycan	77	80	PF01048	0.645
MOD_GlcNHglycan	808	811	PF01048	0.713
MOD_GSK3_1	141	148	PF00069	0.742
MOD_GSK3_1	165	172	PF00069	0.637
MOD_GSK3_1	18	25	PF00069	0.751
MOD_GSK3_1	225	232	PF00069	0.713
MOD_GSK3_1	249	256	PF00069	0.673
MOD_GSK3_1	264	271	PF00069	0.672
MOD_GSK3_1	285	292	PF00069	0.746
MOD_GSK3_1	297	304	PF00069	0.738
MOD_GSK3_1	340	347	PF00069	0.807
MOD_GSK3_1	352	359	PF00069	0.644
MOD_GSK3_1	41	48	PF00069	0.749
MOD_GSK3_1	427	434	PF00069	0.825
MOD_GSK3_1	439	446	PF00069	0.616
MOD_GSK3_1	456	463	PF00069	0.536
MOD_GSK3_1	467	474	PF00069	0.657
MOD_GSK3_1	494	501	PF00069	0.849
MOD_GSK3_1	503	510	PF00069	0.660
MOD_GSK3_1	563	570	PF00069	0.823
MOD_GSK3_1	636	643	PF00069	0.775
MOD_GSK3_1	659	666	PF00069	0.663
MOD_GSK3_1	667	674	PF00069	0.649
MOD_GSK3_1	67	74	PF00069	0.733
MOD_GSK3_1	764	771	PF00069	0.840
MOD_GSK3_1	813	820	PF00069	0.712
MOD_GSK3_1	841	848	PF00069	0.815
MOD_LATS_1	617	623	PF00433	0.640
MOD_LATS_1	762	768	PF00433	0.792
MOD_N-GLC_1	51	56	PF02516	0.761
MOD_N-GLC_1	6	11	PF02516	0.687
MOD_N-GLC_1	691	696	PF02516	0.783
MOD_NEK2_1	24	29	PF00069	0.699
MOD_NEK2_1	368	373	PF00069	0.758
MOD_NEK2_1	571	576	PF00069	0.712
MOD_NEK2_1	739	744	PF00069	0.620
MOD_NEK2_1	75	80	PF00069	0.639
MOD_PIKK_1	486	492	PF00454	0.787
MOD_PIKK_1	503	509	PF00454	0.862
MOD_PIKK_1	820	826	PF00454	0.747
MOD_PIKK_1	845	851	PF00454	0.821
MOD_PKA_1	671	677	PF00069	0.779
MOD_PKA_2	118	124	PF00069	0.580
MOD_PKA_2	178	184	PF00069	0.688
MOD_PKA_2	256	262	PF00069	0.819
MOD_PKA_2	297	303	PF00069	0.794
MOD_PKA_2	468	474	PF00069	0.751
MOD_PKA_2	503	509	PF00069	0.745
MOD_PKA_2	659	665	PF00069	0.734
MOD_PKA_2	671	677	PF00069	0.692
MOD_PKA_2	762	768	PF00069	0.780
MOD_PKA_2	86	92	PF00069	0.752
MOD_PKB_1	106	114	PF00069	0.707
MOD_PKB_1	299	307	PF00069	0.755
MOD_Plk_1	141	147	PF00069	0.661
MOD_Plk_1	169	175	PF00069	0.640
MOD_Plk_1	476	482	PF00069	0.702
MOD_Plk_1	739	745	PF00069	0.775
MOD_Plk_1	99	105	PF00069	0.709
MOD_Plk_4	19	25	PF00069	0.731
MOD_Plk_4	249	255	PF00069	0.728
MOD_Plk_4	563	569	PF00069	0.763
MOD_Plk_4	664	670	PF00069	0.670
MOD_Plk_4	71	77	PF00069	0.581
MOD_Plk_4	99	105	PF00069	0.670
MOD_ProDKin_1	229	235	PF00069	0.755
MOD_ProDKin_1	247	253	PF00069	0.551
MOD_ProDKin_1	309	315	PF00069	0.829
MOD_ProDKin_1	316	322	PF00069	0.757
MOD_ProDKin_1	352	358	PF00069	0.853
MOD_ProDKin_1	385	391	PF00069	0.792
MOD_ProDKin_1	41	47	PF00069	0.818
MOD_ProDKin_1	427	433	PF00069	0.837
MOD_ProDKin_1	443	449	PF00069	0.551
MOD_ProDKin_1	453	459	PF00069	0.653
MOD_ProDKin_1	460	466	PF00069	0.542
MOD_ProDKin_1	489	495	PF00069	0.858
MOD_ProDKin_1	498	504	PF00069	0.652
MOD_ProDKin_1	509	515	PF00069	0.671
MOD_ProDKin_1	636	642	PF00069	0.810
MOD_ProDKin_1	69	75	PF00069	0.712
MOD_ProDKin_1	691	697	PF00069	0.784
MOD_ProDKin_1	813	819	PF00069	0.742
MOD_ProDKin_1	822	828	PF00069	0.733
MOD_ProDKin_1	839	845	PF00069	0.554
MOD_ProDKin_1	848	854	PF00069	0.657
MOD_SUMO_for_1	401	404	PF00179	0.667
MOD_SUMO_for_1	450	453	PF00179	0.650
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.625
TRG_ENDOCYTIC_2	200	203	PF00928	0.708
TRG_ENDOCYTIC_2	526	529	PF00928	0.630
TRG_ER_diArg_1	105	108	PF00400	0.705
TRG_ER_diArg_1	203	205	PF00400	0.613
TRG_ER_diArg_1	298	301	PF00400	0.725
TRG_ER_diArg_1	320	322	PF00400	0.707
TRG_ER_diArg_1	348	351	PF00400	0.782
TRG_ER_diArg_1	537	539	PF00400	0.756
TRG_ER_diArg_1	581	584	PF00400	0.857
TRG_ER_diArg_1	708	710	PF00400	0.764
TRG_ER_diArg_1	761	764	PF00400	0.792
TRG_NES_CRM1_1	100	112	PF08389	0.588
TRG_NLS_Bipartite_1	689	711	PF00514	0.720
TRG_NLS_MonoCore_2	706	711	PF00514	0.726
TRG_Pf-PMV_PEXEL_1	108	112	PF00026	0.698
TRG_Pf-PMV_PEXEL_1	362	366	PF00026	0.642
TRG_Pf-PMV_PEXEL_1	583	588	PF00026	0.648
TRG_Pf-PMV_PEXEL_1	828	833	PF00026	0.753

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HF80	Leishmania braziliensis	55%	98%
A4I2G3	Leishmania infantum	100%	100%
E9AYL6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4Q8V6	Leishmania major	84%	100%