Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X005_LEIDO

TriTrypDb:

LdBPK_261770.1 , LdCL_260023300 , LDHU3_26.2210

Length:

212

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X005

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X005

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.515
CLV_NRD_NRD_1	111	113	PF00675	0.444
CLV_NRD_NRD_1	150	152	PF00675	0.488
CLV_NRD_NRD_1	51	53	PF00675	0.624
CLV_PCSK_FUR_1	109	113	PF00082	0.413
CLV_PCSK_FUR_1	117	121	PF00082	0.395
CLV_PCSK_KEX2_1	111	113	PF00082	0.447
CLV_PCSK_KEX2_1	119	121	PF00082	0.386
CLV_PCSK_KEX2_1	150	152	PF00082	0.518
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.420
CLV_PCSK_SKI1_1	21	25	PF00082	0.581
CLV_PCSK_SKI1_1	53	57	PF00082	0.510
DOC_WW_Pin1_4	1	6	PF00397	0.642
DOC_WW_Pin1_4	7	12	PF00397	0.545
DOC_WW_Pin1_4	75	80	PF00397	0.601
LIG_Clathr_ClatBox_1	133	137	PF01394	0.416
LIG_Clathr_ClatBox_1	143	147	PF01394	0.439
LIG_FHA_1	165	171	PF00498	0.494
LIG_FHA_1	2	8	PF00498	0.623
LIG_FHA_1	27	33	PF00498	0.415
LIG_FHA_2	64	70	PF00498	0.600
LIG_FHA_2	92	98	PF00498	0.566
LIG_Integrin_RGD_1	164	166	PF01839	0.470
LIG_LIR_Apic_2	34	40	PF02991	0.425
LIG_PCNA_PIPBox_1	126	135	PF02747	0.448
LIG_PCNA_yPIPBox_3	119	133	PF02747	0.454
LIG_PCNA_yPIPBox_3	21	32	PF02747	0.452
LIG_SH2_CRK	37	41	PF00017	0.646
LIG_SH2_NCK_1	37	41	PF00017	0.441
LIG_SH2_SRC	132	135	PF00017	0.478
LIG_SH2_STAP1	198	202	PF00017	0.418
LIG_SH2_STAT5	132	135	PF00017	0.498
LIG_SH3_3	5	11	PF00018	0.600
LIG_SH3_3	62	68	PF00018	0.529
LIG_SUMO_SIM_par_1	132	140	PF11976	0.569
LIG_TRAF2_1	176	179	PF00917	0.499
MOD_CK1_1	15	21	PF00069	0.568
MOD_CK2_1	6	12	PF00069	0.604
MOD_CK2_1	91	97	PF00069	0.623
MOD_GlcNHglycan	161	164	PF01048	0.611
MOD_GSK3_1	132	139	PF00069	0.440
MOD_GSK3_1	26	33	PF00069	0.432
MOD_GSK3_1	63	70	PF00069	0.564
MOD_GSK3_1	73	80	PF00069	0.576
MOD_NEK2_1	153	158	PF00069	0.481
MOD_NMyristoyl	1	7	PF02799	0.597
MOD_PIKK_1	182	188	PF00454	0.465
MOD_PIKK_1	89	95	PF00454	0.533
MOD_PKA_2	73	79	PF00069	0.730
MOD_Plk_4	32	38	PF00069	0.428
MOD_ProDKin_1	1	7	PF00069	0.643
MOD_ProDKin_1	75	81	PF00069	0.596
MOD_SUMO_rev_2	63	73	PF00179	0.598
TRG_DiLeu_BaEn_1	190	195	PF01217	0.485
TRG_ENDOCYTIC_2	121	124	PF00928	0.470
TRG_ER_diArg_1	109	112	PF00400	0.376
TRG_ER_diArg_1	149	151	PF00400	0.502
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.549
TRG_Pf-PMV_PEXEL_1	122	126	PF00026	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6B4	Leptomonas seymouri	39%	93%
A4HD51	Leishmania braziliensis	72%	100%
A4I2B1	Leishmania infantum	99%	100%
Q4Q914	Leishmania major	90%	100%