LeishMANIAdb
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BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
BRCT domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WZY6_LEIDO
TriTrypDb:
LdBPK_261210.1 * , LdCL_260017700 , LDHU3_26.1500
Length:
3109

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WZY6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0000075 cell cycle checkpoint signaling 4 1
GO:0000076 DNA replication checkpoint signaling 6 1
GO:0000077 DNA damage checkpoint signaling 5 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006259 DNA metabolic process 4 1
GO:0006270 DNA replication initiation 5 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 112 116 PF00656 0.550
CLV_C14_Caspase3-7 1327 1331 PF00656 0.517
CLV_C14_Caspase3-7 1480 1484 PF00656 0.414
CLV_C14_Caspase3-7 1578 1582 PF00656 0.427
CLV_C14_Caspase3-7 1589 1593 PF00656 0.385
CLV_C14_Caspase3-7 1889 1893 PF00656 0.551
CLV_C14_Caspase3-7 2136 2140 PF00656 0.598
CLV_C14_Caspase3-7 2296 2300 PF00656 0.545
CLV_C14_Caspase3-7 2773 2777 PF00656 0.472
CLV_C14_Caspase3-7 2897 2901 PF00656 0.501
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PD96 Leptomonas seymouri 36% 99%
A4HEX8 Leishmania braziliensis 64% 98%
A4I252 Leishmania infantum 99% 100%
E9AYA2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 97%
Q4Q971 Leishmania major 86% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS