RNA_recognition_motif_(A.k.a._RRM_RBD_or_RNP_doma in)/RNA_recognition_motif._(A.k.a._RRM_RBD_or_RNP_domain)_p utative/Pfam:PF14259/Pfam:PF00076

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA recognition motif (a.k.a. RRM, RBD, or RNP domain), putative

Species:

Leishmania donovani

UniProt:

A0A3S7WZQ8_LEIDO

TriTrypDb:

LdBPK_260750.1 , LdCL_260013200 , LDHU3_26.0990

Length:

154

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WZQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WZQ8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	9
GO:0003723	RNA binding	4	9
GO:0005488	binding	1	9
GO:0097159	organic cyclic compound binding	2	9
GO:1901363	heterocyclic compound binding	2	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	15	17	PF00675	0.542
CLV_NRD_NRD_1	18	20	PF00675	0.539
CLV_PCSK_FUR_1	16	20	PF00082	0.551
CLV_PCSK_KEX2_1	15	17	PF00082	0.542
CLV_PCSK_KEX2_1	150	152	PF00082	0.615
CLV_PCSK_KEX2_1	18	20	PF00082	0.539
CLV_PCSK_PC1ET2_1	150	152	PF00082	0.615
DEG_Nend_UBRbox_2	1	3	PF02207	0.674
DEG_SPOP_SBC_1	5	9	PF00917	0.468
DEG_SPOP_SBC_1	53	57	PF00917	0.490
DOC_USP7_MATH_1	38	42	PF00917	0.419
DOC_USP7_MATH_1	5	9	PF00917	0.468
LIG_14-3-3_CanoR_1	18	27	PF00244	0.628
LIG_Clathr_ClatBox_1	97	101	PF01394	0.476
LIG_deltaCOP1_diTrp_1	43	49	PF00928	0.384
LIG_FHA_2	20	26	PF00498	0.626
LIG_FHA_2	54	60	PF00498	0.450
LIG_LIR_Gen_1	22	30	PF02991	0.570
LIG_LIR_Gen_1	43	53	PF02991	0.324
LIG_LIR_LC3C_4	122	127	PF02991	0.481
LIG_LIR_Nem_3	22	27	PF02991	0.576
LIG_LIR_Nem_3	43	48	PF02991	0.388
LIG_PCNA_PIPBox_1	58	67	PF02747	0.526
LIG_PCNA_yPIPBox_3	58	69	PF02747	0.526
LIG_Pex14_1	45	49	PF04695	0.405
LIG_SH2_NCK_1	95	99	PF00017	0.468
LIG_SH2_STAP1	106	110	PF00017	0.565
LIG_SH2_STAT5	64	67	PF00017	0.552
LIG_SH2_STAT5	75	78	PF00017	0.486
LIG_SH3_3	123	129	PF00018	0.525
LIG_SH3_3	32	38	PF00018	0.503
LIG_SUMO_SIM_par_1	96	102	PF11976	0.451
LIG_TRAF2_1	56	59	PF00917	0.526
LIG_WRC_WIRS_1	65	70	PF05994	0.526
MOD_CK2_1	19	25	PF00069	0.583
MOD_CK2_1	53	59	PF00069	0.490
MOD_CK2_1	64	70	PF00069	0.496
MOD_GlcNHglycan	119	122	PF01048	0.544
MOD_GSK3_1	1	8	PF00069	0.580
MOD_NEK2_1	1	6	PF00069	0.592
MOD_NEK2_1	47	52	PF00069	0.468
MOD_NEK2_2	64	69	PF00069	0.565
MOD_PIKK_1	19	25	PF00454	0.631
MOD_PIKK_1	54	60	PF00454	0.526
MOD_Plk_4	127	133	PF00069	0.443
TRG_ENDOCYTIC_2	24	27	PF00928	0.621
TRG_ENDOCYTIC_2	95	98	PF00928	0.468
TRG_ER_diArg_1	14	16	PF00400	0.555
TRG_ER_diArg_1	17	19	PF00400	0.554
TRG_Pf-PMV_PEXEL_1	108	112	PF00026	0.292

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVV4	Leptomonas seymouri	77%	100%
A0A0S4J314	Bodo saltans	32%	100%
A0A3R7NI30	Trypanosoma rangeli	46%	95%
A4HET3	Leishmania braziliensis	87%	100%
A4I209	Leishmania infantum	100%	100%
C9ZS03	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	97%
E9AY57	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
F4I9J7	Arabidopsis thaliana	34%	76%
Q21832	Caenorhabditis elegans	33%	100%
Q4Q9B6	Leishmania major	96%	100%