LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WZQ3_LEIDO
TriTrypDb:
LdBPK_260400.1 , LdCL_260009500 , LDHU3_26.0510
Length:
100

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WZQ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WZQ3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 32 34 PF00082 0.506
CLV_PCSK_KEX2_1 46 48 PF00082 0.459
CLV_PCSK_PC1ET2_1 32 34 PF00082 0.506
CLV_PCSK_PC1ET2_1 46 48 PF00082 0.459
CLV_PCSK_SKI1_1 16 20 PF00082 0.496
DOC_MAPK_MEF2A_6 68 76 PF00069 0.545
DOC_WW_Pin1_4 61 66 PF00397 0.422
LIG_FHA_1 39 45 PF00498 0.547
LIG_LIR_Nem_3 78 83 PF02991 0.530
LIG_NRP_CendR_1 97 100 PF00754 0.575
LIG_Pex14_1 11 15 PF04695 0.448
LIG_Pex14_1 79 83 PF04695 0.455
LIG_SH2_SRC 42 45 PF00017 0.515
LIG_SH2_STAT5 30 33 PF00017 0.583
LIG_SH2_STAT5 80 83 PF00017 0.434
MOD_CDK_SPxxK_3 61 68 PF00069 0.422
MOD_CK1_1 50 56 PF00069 0.431
MOD_GlcNHglycan 22 25 PF01048 0.673
MOD_PK_1 47 53 PF00069 0.505
MOD_Plk_4 47 53 PF00069 0.516
MOD_ProDKin_1 61 67 PF00069 0.422
MOD_SUMO_rev_2 13 21 PF00179 0.546
TRG_ENDOCYTIC_2 83 86 PF00928 0.488
TRG_ER_diArg_1 97 100 PF00400 0.524

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IK67 Leptomonas seymouri 64% 100%
A4HEP7 Leishmania braziliensis 84% 100%
A4I1X7 Leishmania infantum 100% 100%
C9ZS42 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 45% 100%
E9AY23 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
Q4Q9F0 Leishmania major 95% 100%
V5BQ50 Trypanosoma cruzi 46% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS