Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WZL3_LEIDO

TriTrypDb:

LdBPK_260270.1 , LdCL_260008200 , LDHU3_26.0380

Length:

202


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	3
GO:0016020	membrane	2	2

A0A3S7WZL3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WZL3


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	140	142	PF00675	0.656
CLV_PCSK_KEX2_1	140	142	PF00082	0.669
CLV_PCSK_SKI1_1	119	123	PF00082	0.662
CLV_PCSK_SKI1_1	184	188	PF00082	0.692
DEG_APCC_DBOX_1	139	147	PF00400	0.711
DOC_CYCLIN_RxL_1	76	85	PF00134	0.531
DOC_USP7_MATH_1	82	86	PF00917	0.541
LIG_14-3-3_CanoR_1	133	139	PF00244	0.675
LIG_14-3-3_CanoR_1	4	8	PF00244	0.676
LIG_Actin_WH2_2	184	202	PF00022	0.504
LIG_BIR_III_2	158	162	PF00653	0.681
LIG_FHA_1	113	119	PF00498	0.632
LIG_FHA_1	166	172	PF00498	0.640
LIG_FHA_1	186	192	PF00498	0.712
LIG_FHA_1	38	44	PF00498	0.696
LIG_FHA_1	71	77	PF00498	0.552
LIG_FHA_2	106	112	PF00498	0.672
LIG_FHA_2	94	100	PF00498	0.499
LIG_LIR_Gen_1	39	46	PF02991	0.597
LIG_LIR_Gen_1	85	95	PF02991	0.656
LIG_LIR_Nem_3	39	45	PF02991	0.581
LIG_Rb_pABgroove_1	81	89	PF01858	0.548
LIG_SH2_STAT5	169	172	PF00017	0.638
LIG_SH2_STAT5	194	197	PF00017	0.715
LIG_TRAF2_1	148	151	PF00917	0.727
LIG_UBA3_1	86	91	PF00899	0.538
MOD_GlcNHglycan	92	96	PF01048	0.547
MOD_GSK3_1	170	177	PF00069	0.703
MOD_N-GLC_1	37	42	PF02516	0.638
MOD_NEK2_1	105	110	PF00069	0.614
MOD_NEK2_1	170	175	PF00069	0.673
MOD_NEK2_1	186	191	PF00069	0.682
MOD_NEK2_1	37	42	PF00069	0.699
MOD_NEK2_1	70	75	PF00069	0.516
MOD_NEK2_2	82	87	PF00069	0.624
MOD_NEK2_2	93	98	PF00069	0.456
MOD_NMyristoyl	1	7	PF02799	0.560
MOD_PKA_2	3	9	PF00069	0.682
MOD_Plk_1	37	43	PF00069	0.638
MOD_Plk_4	134	140	PF00069	0.671
MOD_Plk_4	165	171	PF00069	0.715
MOD_Plk_4	37	43	PF00069	0.661
MOD_Plk_4	82	88	PF00069	0.606
MOD_SUMO_for_1	178	181	PF00179	0.633
MOD_SUMO_rev_2	6	11	PF00179	0.638
TRG_DiLeu_BaEn_1	151	156	PF01217	0.697
TRG_ER_diArg_1	139	141	PF00400	0.661


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5J3	Leptomonas seymouri	72%	100%
A0A0S4IJA5	Bodo saltans	24%	79%
A0A1X0NST0	Trypanosomatidae	36%	100%
A0A422NVH2	Trypanosoma rangeli	39%	100%
A4I1W5	Leishmania infantum	99%	100%
C9ZS55	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AIS0	Leishmania braziliensis	81%	100%
E9AY10	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q9G3	Leishmania major	93%	100%
V5DR87	Trypanosoma cruzi	39%	100%