LeishMANIAdb
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Ribosome associated membrane protein RAMP4, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ribosome associated membrane protein RAMP4, putative
Gene product:
Ribosome associated membrane protein RAMP4, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WYU2_LEIDO
TriTrypDb:
LdCL_250006100
Length:
71

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

A0A3S7WYU2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WYU2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 28 30 PF00675 0.490
CLV_PCSK_KEX2_1 27 29 PF00082 0.485
DOC_WW_Pin1_4 63 68 PF00397 0.437
LIG_14-3-3_CanoR_1 12 20 PF00244 0.665
LIG_FHA_1 1 7 PF00498 0.704
LIG_FHA_2 19 25 PF00498 0.690
LIG_PCNA_yPIPBox_3 35 48 PF02747 0.533
LIG_PTB_Apo_2 55 62 PF02174 0.333
LIG_SH2_STAT5 60 63 PF00017 0.499
LIG_SUMO_SIM_anti_2 46 52 PF11976 0.333
LIG_SUMO_SIM_par_1 48 55 PF11976 0.445
MOD_CDK_SPK_2 63 68 PF00069 0.423
MOD_CDK_SPxxK_3 63 70 PF00069 0.448
MOD_CK1_1 13 19 PF00069 0.650
MOD_CK2_1 18 24 PF00069 0.636
MOD_CMANNOS 42 45 PF00535 0.333
MOD_GlcNHglycan 3 6 PF01048 0.420
MOD_GlcNHglycan 36 39 PF01048 0.412
MOD_GSK3_1 59 66 PF00069 0.508
MOD_NEK2_1 43 48 PF00069 0.353
MOD_PIKK_1 13 19 PF00454 0.674
MOD_PKA_2 13 19 PF00069 0.668
MOD_PKB_1 8 16 PF00069 0.684
MOD_Plk_4 52 58 PF00069 0.358
MOD_ProDKin_1 63 69 PF00069 0.439
MOD_SUMO_rev_2 22 26 PF00179 0.647
MOD_SUMO_rev_2 30 37 PF00179 0.645
TRG_ENDOCYTIC_2 60 63 PF00928 0.493
TRG_ER_diArg_1 26 29 PF00400 0.646
TRG_ER_diArg_1 9 12 PF00400 0.638

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I205 Leptomonas seymouri 61% 100%
A4HDV7 Leishmania braziliensis 74% 100%
A4I152 Leishmania infantum 99% 100%
E9AX86 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4QA86 Leishmania major 99% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS