Hypothetical_protein_conserved

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WYT9_LEIDO

TriTrypDb:

LdBPK_250410.1 , LdCL_250009200 , LDHU3_25.0480

Length:

100

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WYT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WYT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	2	6	PF00082	0.498
CLV_PCSK_SKI1_1	35	39	PF00082	0.649
DEG_Nend_UBRbox_1	1	4	PF02207	0.468
DOC_USP7_MATH_1	76	80	PF00917	0.704
DOC_USP7_UBL2_3	2	6	PF12436	0.458
DOC_WW_Pin1_4	17	22	PF00397	0.672
LIG_14-3-3_CanoR_1	58	62	PF00244	0.587
LIG_BRCT_BRCA1_1	38	42	PF00533	0.447
LIG_FHA_1	18	24	PF00498	0.675
LIG_LIR_Gen_1	59	68	PF02991	0.489
LIG_LIR_Nem_3	59	64	PF02991	0.509
LIG_LIR_Nem_3	7	13	PF02991	0.488
LIG_REV1ctd_RIR_1	2	10	PF16727	0.489
LIG_SH2_CRK	10	14	PF00017	0.457
LIG_SH2_CRK	61	65	PF00017	0.537
LIG_SH2_GRB2like	67	70	PF00017	0.590
LIG_SH2_STAT5	67	70	PF00017	0.590
LIG_SH3_3	70	76	PF00018	0.585
LIG_SH3_3	91	97	PF00018	0.726
LIG_TYR_ITIM	8	13	PF00017	0.454
MOD_CK1_1	15	21	PF00069	0.570
MOD_GlcNHglycan	80	83	PF01048	0.575
MOD_NEK2_1	4	9	PF00069	0.562
MOD_PKA_2	57	63	PF00069	0.567
MOD_Plk_4	4	10	PF00069	0.549
MOD_ProDKin_1	17	23	PF00069	0.671
TRG_ENDOCYTIC_2	10	13	PF00928	0.568
TRG_ENDOCYTIC_2	61	64	PF00928	0.509
TRG_Pf-PMV_PEXEL_1	35	40	PF00026	0.485

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W4	Leptomonas seymouri	36%	90%
A4HDY2	Leishmania braziliensis	59%	100%
A4I183	Leishmania infantum	100%	100%
E9AXB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QA55	Leishmania major	86%	100%