LeishMANIAdb
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RNA-binding_protein_putative/GeneDB:LmjF.25.0290

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RNA-binding_protein_putative/GeneDB:LmjF.25.0290
Gene product:
RNA-binding protein, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WYR7_LEIDO
TriTrypDb:
LdBPK_250290.1 , LdCL_250008000 , LDHU3_25.0360
Length:
584

Annotations

Annotations by Jardim et al.

Nucleic acid binding, RNA-binding Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0005730 nucleolus 5 1
GO:0005737 cytoplasm 2 1
GO:0016281 eukaryotic translation initiation factor 4F complex 2 1
GO:0032991 protein-containing complex 1 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1
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Phosphorylation

Promastigote: 520

Expansion

Sequence features

A0A3S7WYR7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WYR7

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 10
GO:0003723 RNA binding 4 4
GO:0005488 binding 1 10
GO:0097159 organic cyclic compound binding 2 10
GO:1901363 heterocyclic compound binding 2 10
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 305 309 PF00656 0.466
CLV_NRD_NRD_1 232 234 PF00675 0.682
CLV_NRD_NRD_1 364 366 PF00675 0.671
CLV_NRD_NRD_1 490 492 PF00675 0.621
CLV_PCSK_KEX2_1 232 234 PF00082 0.682
CLV_PCSK_KEX2_1 364 366 PF00082 0.671
CLV_PCSK_KEX2_1 490 492 PF00082 0.624
CLV_PCSK_SKI1_1 365 369 PF00082 0.547
DEG_SPOP_SBC_1 57 61 PF00917 0.539
DOC_CKS1_1 470 475 PF01111 0.548
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IM94 Leptomonas seymouri 54% 93%
A0A3R7MBU5 Trypanosoma rangeli 34% 100%
A4HDX6 Leishmania braziliensis 80% 100%
A4I171 Leishmania infantum 100% 100%
D0A5F7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
E9AXA5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
Q4QA67 Leishmania major 95% 100%
V5B7N8 Trypanosoma cruzi 36% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS