Trypanosome basal body component protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Trypanosome basal body component protein

Species:

Leishmania donovani

UniProt:

A0A3S7WYM2_LEIDO

TriTrypDb:

LdBPK_242270.1 , LdCL_240028300 , LDHU3_24.2790

Length:

1438

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0000331	contractile vacuole	6	1
GO:0005634	nucleus	5	1
GO:0005773	vacuole	5	1
GO:0005815	microtubule organizing center	2	1
GO:0005929	cilium	4	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0036064	ciliary basal body	3	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1

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Expansion

Sequence features

A0A3S7WYM2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006996	organelle organization	4	1
GO:0009987	cellular process	1	1
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0030030	cell projection organization	4	1
GO:0030031	cell projection assembly	5	1
GO:0044782	cilium organization	5	1
GO:0060271	cilium assembly	6	1
GO:0070925	organelle assembly	5	1
GO:0071840	cellular component organization or biogenesis	2	1

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0008092	cytoskeletal protein binding	3	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	381	385	PF00656	0.566
CLV_C14_Caspase3-7	431	435	PF00656	0.665
CLV_C14_Caspase3-7	638	642	PF00656	0.415
CLV_C14_Caspase3-7	722	726	PF00656	0.632
CLV_C14_Caspase3-7	948	952	PF00656	0.497
CLV_C14_Caspase3-7	971	975	PF00656	0.654
CLV_MEL_PAP_1	950	956	PF00089	0.442
CLV_NRD_NRD_1	1100	1102	PF00675	0.684
CLV_NRD_NRD_1	1191	1193	PF00675	0.581
CLV_NRD_NRD_1	1237	1239	PF00675	0.662

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAZ8	Leptomonas seymouri	55%	100%
A0A1X0NW03	Trypanosomatidae	28%	100%
A4HDS9	Leishmania braziliensis	82%	100%
A4I127	Leishmania infantum	99%	100%
C9ZW83	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9AX64	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QAB2	Leishmania major	94%	100%
V5B9Q6	Trypanosoma cruzi	30%	99%

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