Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WYH7_LEIDO

TriTrypDb:

LdBPK_241190.1 , LdCL_240017000 , LDHU3_24.1400

Length:

1033

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WYH7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WYH7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	265	269	PF00656	0.689
CLV_C14_Caspase3-7	521	525	PF00656	0.656
CLV_C14_Caspase3-7	738	742	PF00656	0.740
CLV_C14_Caspase3-7	785	789	PF00656	0.719
CLV_C14_Caspase3-7	979	983	PF00656	0.687
CLV_NRD_NRD_1	26	28	PF00675	0.664
CLV_NRD_NRD_1	274	276	PF00675	0.652
CLV_NRD_NRD_1	604	606	PF00675	0.785
CLV_NRD_NRD_1	616	618	PF00675	0.742
CLV_NRD_NRD_1	912	914	PF00675	0.565
CLV_NRD_NRD_1	937	939	PF00675	0.626
CLV_NRD_NRD_1	941	943	PF00675	0.627
CLV_PCSK_FUR_1	938	942	PF00082	0.687
CLV_PCSK_KEX2_1	1014	1016	PF00082	0.641
CLV_PCSK_KEX2_1	26	28	PF00082	0.664
CLV_PCSK_KEX2_1	274	276	PF00082	0.652
CLV_PCSK_KEX2_1	604	606	PF00082	0.785
CLV_PCSK_KEX2_1	616	618	PF00082	0.742
CLV_PCSK_KEX2_1	912	914	PF00082	0.565
CLV_PCSK_KEX2_1	937	939	PF00082	0.626
CLV_PCSK_KEX2_1	940	942	PF00082	0.635
CLV_PCSK_PC1ET2_1	1014	1016	PF00082	0.641
CLV_PCSK_PC7_1	937	943	PF00082	0.685
CLV_PCSK_SKI1_1	122	126	PF00082	0.612
CLV_PCSK_SKI1_1	20	24	PF00082	0.776
CLV_PCSK_SKI1_1	453	457	PF00082	0.673
CLV_PCSK_SKI1_1	478	482	PF00082	0.568
CLV_PCSK_SKI1_1	64	68	PF00082	0.799
CLV_PCSK_SKI1_1	824	828	PF00082	0.785
CLV_PCSK_SKI1_1	913	917	PF00082	0.661
DEG_APCC_DBOX_1	15	23	PF00400	0.778
DEG_APCC_DBOX_1	327	335	PF00400	0.672
DEG_Nend_UBRbox_3	1	3	PF02207	0.784
DEG_SPOP_SBC_1	175	179	PF00917	0.736
DEG_SPOP_SBC_1	696	700	PF00917	0.781
DEG_SPOP_SBC_1	834	838	PF00917	0.706
DOC_CKS1_1	33	38	PF01111	0.770
DOC_CYCLIN_RxL_1	643	653	PF00134	0.761
DOC_CYCLIN_RxL_1	753	766	PF00134	0.806
DOC_MAPK_gen_1	511	518	PF00069	0.676
DOC_MAPK_gen_1	940	949	PF00069	0.691
DOC_PP2B_LxvP_1	841	844	PF13499	0.680
DOC_PP2B_LxvP_1	857	860	PF13499	0.753
DOC_PP4_FxxP_1	66	69	PF00568	0.800
DOC_PP4_FxxP_1	99	102	PF00568	0.606
DOC_USP7_MATH_1	168	172	PF00917	0.735
DOC_USP7_MATH_1	244	248	PF00917	0.822
DOC_USP7_MATH_1	288	292	PF00917	0.713
DOC_USP7_MATH_1	346	350	PF00917	0.611
DOC_USP7_MATH_1	43	47	PF00917	0.740
DOC_USP7_MATH_1	451	455	PF00917	0.595
DOC_USP7_MATH_1	467	471	PF00917	0.446
DOC_USP7_MATH_1	483	487	PF00917	0.554
DOC_USP7_MATH_1	573	577	PF00917	0.722
DOC_USP7_MATH_1	600	604	PF00917	0.648
DOC_USP7_MATH_1	768	772	PF00917	0.737
DOC_USP7_MATH_1	77	81	PF00917	0.746
DOC_USP7_MATH_1	819	823	PF00917	0.782
DOC_USP7_MATH_1	834	838	PF00917	0.619
DOC_USP7_MATH_1	899	903	PF00917	0.750
DOC_USP7_MATH_1	960	964	PF00917	0.850
DOC_USP7_UBL2_3	507	511	PF12436	0.625
DOC_WW_Pin1_4	10	15	PF00397	0.730
DOC_WW_Pin1_4	111	116	PF00397	0.680
DOC_WW_Pin1_4	176	181	PF00397	0.736
DOC_WW_Pin1_4	225	230	PF00397	0.745
DOC_WW_Pin1_4	240	245	PF00397	0.826
DOC_WW_Pin1_4	259	264	PF00397	0.533
DOC_WW_Pin1_4	32	37	PF00397	0.653
DOC_WW_Pin1_4	537	542	PF00397	0.709
DOC_WW_Pin1_4	622	627	PF00397	0.763
DOC_WW_Pin1_4	640	645	PF00397	0.577
DOC_WW_Pin1_4	65	70	PF00397	0.798
DOC_WW_Pin1_4	675	680	PF00397	0.805
DOC_WW_Pin1_4	73	78	PF00397	0.679
DOC_WW_Pin1_4	753	758	PF00397	0.830
DOC_WW_Pin1_4	763	768	PF00397	0.688
DOC_WW_Pin1_4	824	829	PF00397	0.839
DOC_WW_Pin1_4	895	900	PF00397	0.807
DOC_WW_Pin1_4	956	961	PF00397	0.827
DOC_WW_Pin1_4	98	103	PF00397	0.749
LIG_14-3-3_CanoR_1	1020	1026	PF00244	0.540
LIG_14-3-3_CanoR_1	1028	1033	PF00244	0.474
LIG_14-3-3_CanoR_1	153	159	PF00244	0.618
LIG_14-3-3_CanoR_1	27	36	PF00244	0.766
LIG_14-3-3_CanoR_1	364	370	PF00244	0.722
LIG_14-3-3_CanoR_1	473	481	PF00244	0.574
LIG_14-3-3_CanoR_1	64	69	PF00244	0.799
LIG_14-3-3_CanoR_1	682	692	PF00244	0.816
LIG_14-3-3_CanoR_1	759	764	PF00244	0.815
LIG_14-3-3_CanoR_1	98	102	PF00244	0.728
LIG_Actin_WH2_2	901	919	PF00022	0.642
LIG_BRCT_BRCA1_1	48	52	PF00533	0.645
LIG_CaM_NSCaTE_8	335	342	PF13499	0.605
LIG_CtBP_PxDLS_1	263	267	PF00389	0.646
LIG_eIF4E_1	273	279	PF01652	0.548
LIG_EVH1_1	391	395	PF00568	0.697
LIG_FHA_1	107	113	PF00498	0.621
LIG_FHA_1	314	320	PF00498	0.682
LIG_FHA_1	421	427	PF00498	0.685
LIG_FHA_1	586	592	PF00498	0.726
LIG_FHA_1	664	670	PF00498	0.777
LIG_FHA_1	730	736	PF00498	0.756
LIG_FHA_1	82	88	PF00498	0.765
LIG_FHA_1	825	831	PF00498	0.817
LIG_FHA_1	944	950	PF00498	0.702
LIG_FHA_2	155	161	PF00498	0.552
LIG_FHA_2	177	183	PF00498	0.729
LIG_FHA_2	250	256	PF00498	0.789
LIG_FHA_2	394	400	PF00498	0.722
LIG_FHA_2	697	703	PF00498	0.738
LIG_FHA_2	845	851	PF00498	0.691
LIG_FHA_2	865	871	PF00498	0.629
LIG_LIR_Apic_2	65	69	PF02991	0.798
LIG_LIR_Apic_2	723	729	PF02991	0.779
LIG_LIR_Apic_2	97	102	PF02991	0.610
LIG_LIR_Gen_1	1005	1016	PF02991	0.655
LIG_LIR_Gen_1	333	343	PF02991	0.556
LIG_LIR_Gen_1	421	429	PF02991	0.626
LIG_LIR_Gen_1	678	684	PF02991	0.747
LIG_LIR_LC3C_4	689	694	PF02991	0.771
LIG_LIR_Nem_3	1005	1011	PF02991	0.661
LIG_LIR_Nem_3	333	338	PF02991	0.535
LIG_LIR_Nem_3	421	427	PF02991	0.538
LIG_PDZ_Class_1	1028	1033	PF00595	0.461
LIG_RPA_C_Fungi	927	939	PF08784	0.581
LIG_SH2_CRK	276	280	PF00017	0.631
LIG_SH2_CRK	424	428	PF00017	0.629
LIG_SH2_NCK_1	1008	1012	PF00017	0.651
LIG_SH2_SRC	1008	1011	PF00017	0.650
LIG_SH2_SRC	337	340	PF00017	0.540
LIG_SH2_STAP1	38	42	PF00017	0.766
LIG_SH2_STAT5	108	111	PF00017	0.625
LIG_SH2_STAT5	337	340	PF00017	0.565
LIG_SH2_STAT5	385	388	PF00017	0.618
LIG_SH3_2	376	381	PF14604	0.702
LIG_SH3_3	109	115	PF00018	0.724
LIG_SH3_3	340	346	PF00018	0.623
LIG_SH3_3	371	377	PF00018	0.798
LIG_SH3_3	389	395	PF00018	0.744
LIG_SH3_3	673	679	PF00018	0.853
LIG_SUMO_SIM_anti_2	689	695	PF11976	0.773
LIG_SUMO_SIM_par_1	210	215	PF11976	0.700
LIG_SUMO_SIM_par_1	689	695	PF11976	0.773
LIG_TRAF2_1	157	160	PF00917	0.660
LIG_TRAF2_1	253	256	PF00917	0.650
LIG_TRAF2_1	462	465	PF00917	0.590
LIG_TRAF2_1	631	634	PF00917	0.745
LIG_TRAF2_1	989	992	PF00917	0.618
MOD_CDC14_SPxK_1	756	759	PF00782	0.799
MOD_CDK_SPK_2	824	829	PF00069	0.786
MOD_CDK_SPxK_1	10	16	PF00069	0.783
MOD_CDK_SPxK_1	640	646	PF00069	0.759
MOD_CDK_SPxK_1	753	759	PF00069	0.795
MOD_CDK_SPxxK_3	65	72	PF00069	0.797
MOD_CDK_SPxxK_3	675	682	PF00069	0.752
MOD_CK1_1	111	117	PF00069	0.698
MOD_CK1_1	171	177	PF00069	0.764
MOD_CK1_1	224	230	PF00069	0.814
MOD_CK1_1	262	268	PF00069	0.745
MOD_CK1_1	28	34	PF00069	0.740
MOD_CK1_1	46	52	PF00069	0.685
MOD_CK1_1	54	60	PF00069	0.752
MOD_CK1_1	540	546	PF00069	0.597
MOD_CK1_1	649	655	PF00069	0.790
MOD_CK1_1	68	74	PF00069	0.694
MOD_CK1_1	686	692	PF00069	0.733
MOD_CK1_1	695	701	PF00069	0.788
MOD_CK1_1	742	748	PF00069	0.841
MOD_CK1_1	797	803	PF00069	0.703
MOD_CK1_1	80	86	PF00069	0.602
MOD_CK1_1	811	817	PF00069	0.750
MOD_CK1_1	822	828	PF00069	0.671
MOD_CK1_1	891	897	PF00069	0.825
MOD_CK1_1	952	958	PF00069	0.793
MOD_CK1_1	959	965	PF00069	0.726
MOD_CK1_1	97	103	PF00069	0.635
MOD_CK2_1	154	160	PF00069	0.618
MOD_CK2_1	249	255	PF00069	0.746
MOD_CK2_1	338	344	PF00069	0.590
MOD_CK2_1	451	457	PF00069	0.595
MOD_CK2_1	553	559	PF00069	0.818
MOD_CK2_1	864	870	PF00069	0.792
MOD_Cter_Amidation	614	617	PF01082	0.797
MOD_DYRK1A_RPxSP_1	824	828	PF00069	0.785
MOD_GlcNHglycan	131	134	PF01048	0.752
MOD_GlcNHglycan	170	173	PF01048	0.750
MOD_GlcNHglycan	185	188	PF01048	0.567
MOD_GlcNHglycan	204	207	PF01048	0.503
MOD_GlcNHglycan	223	226	PF01048	0.809
MOD_GlcNHglycan	290	293	PF01048	0.703
MOD_GlcNHglycan	3	6	PF01048	0.782
MOD_GlcNHglycan	340	343	PF01048	0.693
MOD_GlcNHglycan	43	46	PF01048	0.612
MOD_GlcNHglycan	485	488	PF01048	0.587
MOD_GlcNHglycan	555	558	PF01048	0.813
MOD_GlcNHglycan	56	59	PF01048	0.577
MOD_GlcNHglycan	561	564	PF01048	0.708
MOD_GlcNHglycan	567	570	PF01048	0.601
MOD_GlcNHglycan	606	609	PF01048	0.732
MOD_GlcNHglycan	633	638	PF01048	0.747
MOD_GlcNHglycan	640	643	PF01048	0.664
MOD_GlcNHglycan	655	658	PF01048	0.542
MOD_GlcNHglycan	694	697	PF01048	0.846
MOD_GlcNHglycan	79	82	PF01048	0.763
MOD_GlcNHglycan	811	814	PF01048	0.848
MOD_GlcNHglycan	824	827	PF01048	0.641
MOD_GlcNHglycan	837	840	PF01048	0.643
MOD_GlcNHglycan	875	878	PF01048	0.791
MOD_GlcNHglycan	901	904	PF01048	0.646
MOD_GlcNHglycan	91	94	PF01048	0.620
MOD_GlcNHglycan	954	957	PF01048	0.755
MOD_GSK3_1	171	178	PF00069	0.612
MOD_GSK3_1	221	228	PF00069	0.670
MOD_GSK3_1	236	243	PF00069	0.767
MOD_GSK3_1	258	265	PF00069	0.726
MOD_GSK3_1	28	35	PF00069	0.767
MOD_GSK3_1	393	400	PF00069	0.725
MOD_GSK3_1	41	48	PF00069	0.529
MOD_GSK3_1	416	423	PF00069	0.571
MOD_GSK3_1	50	57	PF00069	0.633
MOD_GSK3_1	559	566	PF00069	0.803
MOD_GSK3_1	583	590	PF00069	0.763
MOD_GSK3_1	600	607	PF00069	0.580
MOD_GSK3_1	633	640	PF00069	0.776
MOD_GSK3_1	64	71	PF00069	0.605
MOD_GSK3_1	646	653	PF00069	0.617
MOD_GSK3_1	683	690	PF00069	0.729
MOD_GSK3_1	692	699	PF00069	0.780
MOD_GSK3_1	73	80	PF00069	0.666
MOD_GSK3_1	739	746	PF00069	0.779
MOD_GSK3_1	759	766	PF00069	0.589
MOD_GSK3_1	782	789	PF00069	0.583
MOD_GSK3_1	790	797	PF00069	0.636
MOD_GSK3_1	891	898	PF00069	0.821
MOD_GSK3_1	94	101	PF00069	0.672
MOD_GSK3_1	952	959	PF00069	0.799
MOD_N-GLC_1	1	6	PF02516	0.783
MOD_N-GLC_1	129	134	PF02516	0.763
MOD_N-GLC_1	183	188	PF02516	0.688
MOD_N-GLC_1	283	288	PF02516	0.493
MOD_N-GLC_1	408	413	PF02516	0.624
MOD_N-GLC_1	550	555	PF02516	0.766
MOD_N-GLC_1	696	701	PF02516	0.815
MOD_N-GLC_1	705	710	PF02516	0.738
MOD_N-GLC_1	864	869	PF02516	0.785
MOD_N-GLC_1	949	954	PF02516	0.749
MOD_N-GLC_2	577	579	PF02516	0.778
MOD_NEK2_1	1	6	PF00069	0.783
MOD_NEK2_1	154	159	PF00069	0.545
MOD_NEK2_1	223	228	PF00069	0.754
MOD_NEK2_1	25	30	PF00069	0.768
MOD_NEK2_1	283	288	PF00069	0.591
MOD_NEK2_1	338	343	PF00069	0.586
MOD_NEK2_1	365	370	PF00069	0.657
MOD_NEK2_1	50	55	PF00069	0.755
MOD_NEK2_1	506	511	PF00069	0.667
MOD_NEK2_1	638	643	PF00069	0.733
MOD_NEK2_1	650	655	PF00069	0.629
MOD_NEK2_1	660	665	PF00069	0.630
MOD_NEK2_1	683	688	PF00069	0.702
MOD_NEK2_1	692	697	PF00069	0.746
MOD_NEK2_1	751	756	PF00069	0.789
MOD_NEK2_2	108	113	PF00069	0.730
MOD_NEK2_2	244	249	PF00069	0.763
MOD_NEK2_2	819	824	PF00069	0.737
MOD_PIKK_1	467	473	PF00454	0.644
MOD_PIKK_1	663	669	PF00454	0.733
MOD_PK_1	587	593	PF00069	0.742
MOD_PK_1	620	626	PF00069	0.662
MOD_PK_1	727	733	PF00069	0.687
MOD_PKA_1	604	610	PF00069	0.741
MOD_PKA_2	25	31	PF00069	0.664
MOD_PKA_2	344	350	PF00069	0.809
MOD_PKA_2	472	478	PF00069	0.600
MOD_PKA_2	604	610	PF00069	0.685
MOD_PKA_2	663	669	PF00069	0.774
MOD_PKA_2	790	796	PF00069	0.797
MOD_PKA_2	870	876	PF00069	0.793
MOD_PKA_2	943	949	PF00069	0.694
MOD_PKA_2	97	103	PF00069	0.678
MOD_PKA_2	970	976	PF00069	0.728
MOD_Plk_1	283	289	PF00069	0.667
MOD_Plk_1	295	301	PF00069	0.563
MOD_Plk_1	408	414	PF00069	0.649
MOD_Plk_1	420	426	PF00069	0.670
MOD_Plk_1	451	457	PF00069	0.569
MOD_Plk_1	751	757	PF00069	0.687
MOD_Plk_1	949	955	PF00069	0.755
MOD_Plk_2-3	786	792	PF00069	0.605
MOD_Plk_4	236	242	PF00069	0.657
MOD_Plk_4	330	336	PF00069	0.675
MOD_Plk_4	381	387	PF00069	0.619
MOD_Plk_4	408	414	PF00069	0.624
MOD_Plk_4	451	457	PF00069	0.460
MOD_Plk_4	46	52	PF00069	0.749
MOD_Plk_4	687	693	PF00069	0.765
MOD_ProDKin_1	10	16	PF00069	0.733
MOD_ProDKin_1	111	117	PF00069	0.678
MOD_ProDKin_1	176	182	PF00069	0.734
MOD_ProDKin_1	225	231	PF00069	0.745
MOD_ProDKin_1	240	246	PF00069	0.826
MOD_ProDKin_1	259	265	PF00069	0.526
MOD_ProDKin_1	32	38	PF00069	0.655
MOD_ProDKin_1	537	543	PF00069	0.718
MOD_ProDKin_1	622	628	PF00069	0.764
MOD_ProDKin_1	640	646	PF00069	0.580
MOD_ProDKin_1	65	71	PF00069	0.797
MOD_ProDKin_1	675	681	PF00069	0.805
MOD_ProDKin_1	73	79	PF00069	0.679
MOD_ProDKin_1	753	759	PF00069	0.832
MOD_ProDKin_1	763	769	PF00069	0.686
MOD_ProDKin_1	824	830	PF00069	0.839
MOD_ProDKin_1	895	901	PF00069	0.798
MOD_ProDKin_1	956	962	PF00069	0.830
MOD_ProDKin_1	98	104	PF00069	0.748
MOD_SUMO_rev_2	470	480	PF00179	0.494
MOD_SUMO_rev_2	521	527	PF00179	0.656
MOD_SUMO_rev_2	737	742	PF00179	0.784
TRG_DiLeu_BaEn_1	327	332	PF01217	0.608
TRG_DiLeu_BaEn_1	634	639	PF01217	0.750
TRG_DiLeu_BaLyEn_6	315	320	PF01217	0.684
TRG_ENDOCYTIC_2	1008	1011	PF00928	0.650
TRG_ENDOCYTIC_2	276	279	PF00928	0.655
TRG_ENDOCYTIC_2	424	427	PF00928	0.628
TRG_ENDOCYTIC_2	499	502	PF00928	0.666
TRG_ER_diArg_1	120	123	PF00400	0.636
TRG_ER_diArg_1	25	27	PF00400	0.667
TRG_ER_diArg_1	273	275	PF00400	0.700
TRG_ER_diArg_1	747	750	PF00400	0.838
TRG_ER_diArg_1	911	913	PF00400	0.609
TRG_ER_diArg_1	937	940	PF00400	0.679
TRG_NES_CRM1_1	984	999	PF08389	0.681
TRG_Pf-PMV_PEXEL_1	318	322	PF00026	0.675
TRG_Pf-PMV_PEXEL_1	432	436	PF00026	0.626
TRG_Pf-PMV_PEXEL_1	440	444	PF00026	0.597
TRG_Pf-PMV_PEXEL_1	528	533	PF00026	0.672
TRG_Pf-PMV_PEXEL_1	759	764	PF00026	0.815
TRG_Pf-PMV_PEXEL_1	988	992	PF00026	0.622

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HDH3	Leishmania braziliensis	64%	97%
A4I0V4	Leishmania infantum	99%	100%
E9AWV8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	93%
Q4QAL6	Leishmania major	87%	100%