Calmodulin-binding_putative/Pfam:PF13864

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Calmodulin-binding, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WY66_LEIDO

TriTrypDb:

LdBPK_240100.1 , LdCL_240005900 , LDHU3_24.0120

Length:

279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7WY66

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WY66

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0005516	calmodulin binding	3	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	11	15	PF00656	0.519
CLV_C14_Caspase3-7	60	64	PF00656	0.561
CLV_NRD_NRD_1	188	190	PF00675	0.370
CLV_NRD_NRD_1	224	226	PF00675	0.298
CLV_NRD_NRD_1	35	37	PF00675	0.630
CLV_NRD_NRD_1	69	71	PF00675	0.651
CLV_NRD_NRD_1	90	92	PF00675	0.629
CLV_PCSK_KEX2_1	224	226	PF00082	0.296
CLV_PCSK_KEX2_1	35	37	PF00082	0.591
CLV_PCSK_SKI1_1	190	194	PF00082	0.296

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3N8	Leptomonas seymouri	75%	100%
A0A0S4IY56	Bodo saltans	44%	100%
A0A1X0NJ07	Trypanosomatidae	59%	100%
A0A3R7RTB5	Trypanosoma rangeli	57%	100%
A0A4X1TZW7	Sus scrofa	25%	100%
D0A6Y1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	100%
E1B836	Bos taurus	25%	100%
E9AH22	Leishmania infantum	100%	100%
E9AI83	Leishmania braziliensis	25%	100%
E9AUG8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%

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