Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WY14_LEIDO

TriTrypDb:

LdBPK_231770.1 , LdCL_230024800 , LDHU3_23.2340

Length:

138


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

A0A3S7WY14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WY14


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	82	86	PF00656	0.661
CLV_NRD_NRD_1	121	123	PF00675	0.371
CLV_NRD_NRD_1	16	18	PF00675	0.666
CLV_NRD_NRD_1	22	24	PF00675	0.651
CLV_PCSK_KEX2_1	121	123	PF00082	0.371
CLV_PCSK_KEX2_1	129	131	PF00082	0.380
CLV_PCSK_KEX2_1	22	24	PF00082	0.749
CLV_PCSK_PC1ET2_1	129	131	PF00082	0.486
CLV_PCSK_SKI1_1	130	134	PF00082	0.410
CLV_PCSK_SKI1_1	18	22	PF00082	0.689
CLV_PCSK_SKI1_1	29	33	PF00082	0.649
DOC_CYCLIN_RxL_1	23	34	PF00134	0.502
DOC_USP7_MATH_1	132	136	PF00917	0.653
DOC_USP7_UBL2_3	29	33	PF12436	0.421
DOC_USP7_UBL2_3	77	81	PF12436	0.583
LIG_Actin_WH2_2	29	46	PF00022	0.483
LIG_BIR_II_1	1	5	PF00653	0.470
LIG_deltaCOP1_diTrp_1	85	91	PF00928	0.612
LIG_FHA_1	19	25	PF00498	0.447
LIG_FHA_1	54	60	PF00498	0.370
LIG_LIR_Apic_2	41	45	PF02991	0.399
LIG_LIR_Gen_1	109	118	PF02991	0.587
LIG_LIR_Nem_3	108	114	PF02991	0.600
LIG_LIR_Nem_3	88	94	PF02991	0.614
LIG_Pex14_1	87	91	PF04695	0.617
LIG_SH2_STAP1	10	14	PF00017	0.507
LIG_SH2_STAT5	111	114	PF00017	0.590
LIG_SH2_STAT5	15	18	PF00017	0.451
LIG_SH2_STAT5	42	45	PF00017	0.479
LIG_SH3_4	29	36	PF00018	0.414
LIG_TRAF2_2	105	110	PF00917	0.699
LIG_TYR_ITSM	107	114	PF00017	0.604
LIG_WRC_WIRS_1	54	59	PF05994	0.437
MOD_CK2_1	110	116	PF00069	0.606
MOD_GSK3_1	106	113	PF00069	0.611
MOD_GSK3_1	53	60	PF00069	0.437
MOD_NEK2_1	31	36	PF00069	0.398
MOD_NEK2_1	57	62	PF00069	0.475
MOD_PKA_2	43	49	PF00069	0.403
MOD_Plk_2-3	110	116	PF00069	0.590
TRG_DiLeu_BaLyEn_6	27	32	PF01217	0.497
TRG_ENDOCYTIC_2	111	114	PF00928	0.590
TRG_ER_diArg_1	22	24	PF00400	0.537


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDE3	Leptomonas seymouri	81%	99%
A0A0S4ILZ1	Bodo saltans	55%	100%
A0A1X0NXD3	Trypanosomatidae	60%	93%
A0A422NJI6	Trypanosoma rangeli	59%	98%
A4HD22	Leishmania braziliensis	92%	100%
A4I0K9	Leishmania infantum	100%	100%
C9ZVI3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	99%
E9AWH0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4QB01	Leishmania major	98%	100%
V5BFT8	Trypanosoma cruzi	66%	95%