LeishMANIAdb
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Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Transmembrane protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7WXZ7_LEIDO
TriTrypDb:
LdBPK_231840.1 * , LdCL_230025500 , LDHU3_23.2420
Length:
149

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXZ7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXZ7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 114 116 PF00675 0.369
CLV_PCSK_KEX2_1 114 116 PF00082 0.369
CLV_PCSK_SKI1_1 114 118 PF00082 0.364
DEG_APCC_DBOX_1 50 58 PF00400 0.316
DEG_SCF_FBW7_1 140 147 PF00400 0.567
DOC_CKS1_1 141 146 PF01111 0.568
DOC_MAPK_gen_1 21 31 PF00069 0.538
DOC_MAPK_gen_1 93 102 PF00069 0.518
DOC_MAPK_HePTP_8 90 102 PF00069 0.514
DOC_MAPK_MEF2A_6 24 31 PF00069 0.530
DOC_MAPK_MEF2A_6 87 96 PF00069 0.515
DOC_MAPK_MEF2A_6 97 104 PF00069 0.523
DOC_MAPK_NFAT4_5 24 32 PF00069 0.400
DOC_PP2B_LxvP_1 102 105 PF13499 0.536
DOC_PP2B_LxvP_1 41 44 PF13499 0.199
DOC_USP7_MATH_1 136 140 PF00917 0.565
DOC_USP7_MATH_1 144 148 PF00917 0.565
DOC_USP7_MATH_1 56 60 PF00917 0.318
DOC_WW_Pin1_4 117 122 PF00397 0.552
DOC_WW_Pin1_4 140 145 PF00397 0.569
LIG_14-3-3_CanoR_1 55 61 PF00244 0.318
LIG_14-3-3_CanoR_1 63 68 PF00244 0.344
LIG_14-3-3_CanoR_1 69 74 PF00244 0.199
LIG_14-3-3_CanoR_1 95 101 PF00244 0.519
LIG_MAD2 4 12 PF02301 0.557
LIG_SH2_STAP1 80 84 PF00017 0.199
LIG_SH2_STAT5 53 56 PF00017 0.318
LIG_SH3_3 82 88 PF00018 0.199
MOD_CDC14_SPxK_1 120 123 PF00782 0.552
MOD_CDK_SPxK_1 117 123 PF00069 0.555
MOD_CK1_1 139 145 PF00069 0.569
MOD_CK1_1 58 64 PF00069 0.332
MOD_GlcNHglycan 105 108 PF01048 0.348
MOD_GlcNHglycan 41 44 PF01048 0.199
MOD_GSK3_1 136 143 PF00069 0.567
MOD_GSK3_1 96 103 PF00069 0.521
MOD_NEK2_1 49 54 PF00069 0.315
MOD_PKA_2 10 16 PF00069 0.559
MOD_PKA_2 96 102 PF00069 0.518
MOD_Plk_4 136 142 PF00069 0.567
MOD_Plk_4 75 81 PF00069 0.199
MOD_ProDKin_1 117 123 PF00069 0.555
MOD_ProDKin_1 140 146 PF00069 0.569
TRG_ER_diArg_1 92 95 PF00400 0.510

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS