LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WXZ3_LEIDO
TriTrypDb:
LdBPK_240030.1 , LdCL_240005200 , LDHU3_24.0050
Length:
166

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXZ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXZ3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 106 108 PF00675 0.399
CLV_NRD_NRD_1 129 131 PF00675 0.605
CLV_NRD_NRD_1 145 147 PF00675 0.477
CLV_NRD_NRD_1 164 166 PF00675 0.718
CLV_NRD_NRD_1 46 48 PF00675 0.612
CLV_PCSK_KEX2_1 137 139 PF00082 0.517
CLV_PCSK_KEX2_1 145 147 PF00082 0.605
CLV_PCSK_KEX2_1 46 48 PF00082 0.612
CLV_PCSK_PC1ET2_1 137 139 PF00082 0.508
CLV_PCSK_SKI1_1 58 62 PF00082 0.419
CLV_PCSK_SKI1_1 84 88 PF00082 0.406
DEG_APCC_KENBOX_2 107 111 PF00400 0.416
DEG_Nend_UBRbox_1 1 4 PF02207 0.493
DOC_MAPK_gen_1 107 114 PF00069 0.435
DOC_PP1_RVXF_1 56 63 PF00149 0.337
DOC_USP7_MATH_1 95 99 PF00917 0.462
DOC_USP7_UBL2_3 133 137 PF12436 0.491
DOC_WW_Pin1_4 26 31 PF00397 0.468
LIG_14-3-3_CanoR_1 152 157 PF00244 0.614
LIG_14-3-3_CanoR_1 58 63 PF00244 0.413
LIG_14-3-3_CanoR_1 65 70 PF00244 0.524
LIG_BRCT_BRCA1_1 100 104 PF00533 0.401
LIG_LIR_Nem_3 101 106 PF02991 0.399
LIG_LIR_Nem_3 61 66 PF02991 0.462
LIG_LIR_Nem_3 68 72 PF02991 0.349
LIG_MLH1_MIPbox_1 100 104 PF16413 0.401
LIG_REV1ctd_RIR_1 101 112 PF16727 0.394
LIG_SH2_CRK 90 94 PF00017 0.465
LIG_SH3_1 47 53 PF00018 0.530
LIG_SH3_2 41 46 PF14604 0.586
LIG_SH3_3 38 44 PF00018 0.594
LIG_SH3_3 47 53 PF00018 0.655
LIG_TYR_ITIM 88 93 PF00017 0.483
LIG_WRC_WIRS_1 59 64 PF05994 0.382
LIG_WRC_WIRS_1 66 71 PF05994 0.410
LIG_WW_3 162 166 PF00397 0.538
MOD_CK1_1 98 104 PF00069 0.436
MOD_GlcNHglycan 117 120 PF01048 0.461
MOD_GlcNHglycan 97 100 PF01048 0.421
MOD_GSK3_1 152 159 PF00069 0.563
MOD_Plk_4 65 71 PF00069 0.485
MOD_ProDKin_1 26 32 PF00069 0.472
MOD_SUMO_rev_2 129 139 PF00179 0.598
TRG_DiLeu_BaLyEn_6 55 60 PF01217 0.443
TRG_ENDOCYTIC_2 90 93 PF00928 0.469

Homologs

Protein Taxonomy Sequence identity Coverage
A0A1X0NIP0 Trypanosomatidae 43% 98%
A0A422P424 Trypanosoma rangeli 40% 100%
A4HD61 Leishmania braziliensis 80% 100%
A4I0M6 Leishmania infantum 99% 100%
D0A6X4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 95%
E9AWJ3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QAX7 Leishmania major 91% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS