Inositol hexakisphosphate, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Inositol hexakisphosphate, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WXW2_LEIDO

TriTrypDb:

LdBPK_231720.1 , LdCL_230024300 , LDHU3_23.2280

Length:

1724

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7WXW2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0004721	phosphoprotein phosphatase activity	3	1
GO:0004725	protein tyrosine phosphatase activity	4	1
GO:0016787	hydrolase activity	2	1
GO:0016788	hydrolase activity, acting on ester bonds	3	1
GO:0016791	phosphatase activity	5	1
GO:0042578	phosphoric ester hydrolase activity	4	1
GO:0140096	catalytic activity, acting on a protein	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1021	1025	PF00656	0.449
CLV_C14_Caspase3-7	1716	1720	PF00656	0.353
CLV_C14_Caspase3-7	220	224	PF00656	0.699
CLV_NRD_NRD_1	1015	1017	PF00675	0.329
CLV_NRD_NRD_1	104	106	PF00675	0.608
CLV_NRD_NRD_1	1206	1208	PF00675	0.313
CLV_NRD_NRD_1	1307	1309	PF00675	0.419
CLV_NRD_NRD_1	1342	1344	PF00675	0.355
CLV_NRD_NRD_1	139	141	PF00675	0.684
CLV_NRD_NRD_1	1551	1553	PF00675	0.344

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ43	Leptomonas seymouri	67%	100%
A0A0S4IQV4	Bodo saltans	50%	100%
A0A1X0NWP0	Trypanosomatidae	59%	100%
A0A422NXX2	Trypanosoma rangeli	57%	100%
A4HD18	Leishmania braziliensis	81%	99%
A4I0K4	Leishmania infantum	100%	100%
C9ZVD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
E9AWG5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QB06	Leishmania major	95%	100%
V5AZ77	Trypanosoma cruzi	59%	100%

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