LeishMANIAdb
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SNF2 family N-terminal domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
SNF2 family N-terminal domain containing protein, putative
Gene product:
SNF2 family N-terminal domain containing protein, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WXU6_LEIDO
TriTrypDb:
LdCL_230018200
Length:
238

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXU6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXU6

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 2
GO:0003824 catalytic activity 1 2
GO:0005488 binding 1 2
GO:0005524 ATP binding 5 2
GO:0008094 ATP-dependent activity, acting on DNA 2 2
GO:0017076 purine nucleotide binding 4 2
GO:0030554 adenyl nucleotide binding 5 2
GO:0032553 ribonucleotide binding 3 2
GO:0032555 purine ribonucleotide binding 4 2
GO:0032559 adenyl ribonucleotide binding 5 2
GO:0035639 purine ribonucleoside triphosphate binding 4 2
GO:0036094 small molecule binding 2 2
GO:0043167 ion binding 2 2
GO:0043168 anion binding 3 2
GO:0097159 organic cyclic compound binding 2 2
GO:0097367 carbohydrate derivative binding 2 2
GO:0140097 catalytic activity, acting on DNA 3 2
GO:0140640 catalytic activity, acting on a nucleic acid 2 2
GO:0140657 ATP-dependent activity 1 2
GO:0140658 ATP-dependent chromatin remodeler activity 3 2
GO:1901265 nucleoside phosphate binding 3 2
GO:1901363 heterocyclic compound binding 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 118 122 PF00656 0.400
CLV_NRD_NRD_1 144 146 PF00675 0.199
CLV_NRD_NRD_1 156 158 PF00675 0.199
CLV_NRD_NRD_1 224 226 PF00675 0.316
CLV_PCSK_KEX2_1 144 146 PF00082 0.199
CLV_PCSK_KEX2_1 156 158 PF00082 0.199
CLV_PCSK_KEX2_1 224 226 PF00082 0.316
CLV_PCSK_SKI1_1 159 163 PF00082 0.199
CLV_PCSK_SKI1_1 218 222 PF00082 0.339
CLV_PCSK_SKI1_1 69 73 PF00082 0.199
CLV_PCSK_SKI1_1 84 88 PF00082 0.199
DEG_SPOP_SBC_1 202 206 PF00917 0.442
DOC_CKS1_1 15 20 PF01111 0.485
DOC_CKS1_1 26 31 PF01111 0.400
DOC_CYCLIN_yCln2_LP_2 149 155 PF00134 0.400
DOC_MAPK_gen_1 144 153 PF00069 0.400
DOC_MAPK_gen_1 64 73 PF00069 0.400
DOC_PP1_RVXF_1 49 55 PF00149 0.400
DOC_PP1_RVXF_1 67 74 PF00149 0.400
DOC_PP1_SILK_1 159 164 PF00149 0.400
DOC_PP2B_LxvP_1 149 152 PF13499 0.400
DOC_PP4_FxxP_1 105 108 PF00568 0.400
DOC_USP7_MATH_1 127 131 PF00917 0.400
DOC_USP7_MATH_1 180 184 PF00917 0.400
DOC_USP7_MATH_1 202 206 PF00917 0.442
DOC_WW_Pin1_4 14 19 PF00397 0.485
DOC_WW_Pin1_4 22 27 PF00397 0.462
DOC_WW_Pin1_4 87 92 PF00397 0.400
LIG_14-3-3_CanoR_1 10 18 PF00244 0.461
LIG_14-3-3_CanoR_1 216 221 PF00244 0.349
LIG_14-3-3_CanoR_1 47 54 PF00244 0.400
LIG_BRCT_BRCA1_1 113 117 PF00533 0.400
LIG_BRCT_BRCA1_1 216 220 PF00533 0.355
LIG_BRCT_BRCA1_1 69 73 PF00533 0.400
LIG_BRCT_BRCA1_2 69 75 PF00533 0.400
LIG_EH1_1 79 87 PF00400 0.400
LIG_FHA_1 26 32 PF00498 0.199
LIG_FHA_1 47 53 PF00498 0.400
LIG_FHA_1 60 66 PF00498 0.400
LIG_FHA_1 94 100 PF00498 0.400
LIG_FHA_2 226 232 PF00498 0.347
LIG_LIR_Gen_1 114 125 PF02991 0.400
LIG_LIR_Gen_1 171 180 PF02991 0.400
LIG_LIR_Gen_1 53 59 PF02991 0.400
LIG_LIR_Gen_1 98 108 PF02991 0.400
LIG_LIR_Nem_3 114 120 PF02991 0.400
LIG_LIR_Nem_3 171 175 PF02991 0.400
LIG_LIR_Nem_3 53 57 PF02991 0.400
LIG_LIR_Nem_3 70 76 PF02991 0.400
LIG_LIR_Nem_3 98 103 PF02991 0.400
LIG_NRBOX 137 143 PF00104 0.400
LIG_NRBOX 98 104 PF00104 0.400
LIG_SH2_CRK 172 176 PF00017 0.400
LIG_SH3_1 23 29 PF00018 0.440
LIG_SH3_3 12 18 PF00018 0.471
LIG_SH3_3 171 177 PF00018 0.400
LIG_SH3_3 23 29 PF00018 0.440
LIG_SH3_5 168 172 PF00018 0.400
LIG_SUMO_SIM_anti_2 28 34 PF11976 0.199
LIG_SUMO_SIM_par_1 55 62 PF11976 0.400
LIG_TRAF2_1 228 231 PF00917 0.359
MOD_CDK_SPxxK_3 87 94 PF00069 0.199
MOD_CK1_1 128 134 PF00069 0.199
MOD_CK1_1 209 215 PF00069 0.408
MOD_CK1_1 22 28 PF00069 0.455
MOD_CK2_1 128 134 PF00069 0.199
MOD_CK2_1 225 231 PF00069 0.337
MOD_DYRK1A_RPxSP_1 14 18 PF00069 0.484
MOD_GlcNHglycan 121 124 PF01048 0.199
MOD_GlcNHglycan 130 133 PF01048 0.199
MOD_GlcNHglycan 182 185 PF01048 0.199
MOD_GlcNHglycan 198 201 PF01048 0.446
MOD_GlcNHglycan 42 45 PF01048 0.199
MOD_GSK3_1 107 114 PF00069 0.199
MOD_GSK3_1 157 164 PF00069 0.199
MOD_GSK3_1 202 209 PF00069 0.441
MOD_GSK3_1 214 221 PF00069 0.356
MOD_GSK3_1 225 232 PF00069 0.345
MOD_GSK3_1 36 43 PF00069 0.199
MOD_NEK2_1 125 130 PF00069 0.199
MOD_NEK2_1 46 51 PF00069 0.199
MOD_NEK2_1 85 90 PF00069 0.199
MOD_OFUCOSY 227 233 PF10250 0.369
MOD_PIKK_1 211 217 PF00454 0.389
MOD_PIKK_1 59 65 PF00454 0.199
MOD_PIKK_1 9 15 PF00454 0.445
MOD_PK_1 157 163 PF00069 0.199
MOD_PKA_2 128 134 PF00069 0.199
MOD_PKA_2 46 52 PF00069 0.199
MOD_PKA_2 9 15 PF00069 0.445
MOD_PKB_1 216 224 PF00069 0.344
MOD_Plk_1 157 163 PF00069 0.199
MOD_Plk_4 107 113 PF00069 0.199
MOD_ProDKin_1 14 20 PF00069 0.486
MOD_ProDKin_1 22 28 PF00069 0.455
MOD_ProDKin_1 87 93 PF00069 0.199
TRG_DiLeu_BaEn_1 137 142 PF01217 0.199
TRG_DiLeu_BaEn_1 98 103 PF01217 0.199
TRG_DiLeu_BaLyEn_6 145 150 PF01217 0.199
TRG_DiLeu_BaLyEn_6 174 179 PF01217 0.199
TRG_ENDOCYTIC_2 172 175 PF00928 0.199
TRG_ER_diArg_1 144 146 PF00400 0.199
TRG_ER_diArg_1 155 157 PF00400 0.199
TRG_ER_diArg_1 223 225 PF00400 0.335

Homologs

Protein Taxonomy Sequence identity Coverage
P70270 MOUSE 26% 32%
Q92698 HUMAN 25% 32%
Q9XFH4 ARATH 31% 31%
Q9ZUL5 ARATH 31% 31%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS