LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7WXU4_LEIDO
TriTrypDb:
LdBPK_231520.1 , LdCL_230022300 , LDHU3_23.2030
Length:
378

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5
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Expansion

Sequence features

A0A3S7WXU4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXU4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 308 312 PF00656 0.720
CLV_NRD_NRD_1 12 14 PF00675 0.452
CLV_NRD_NRD_1 220 222 PF00675 0.579
CLV_PCSK_KEX2_1 12 14 PF00082 0.452
CLV_PCSK_KEX2_1 220 222 PF00082 0.579
DEG_SCF_FBW7_1 209 214 PF00400 0.732
DEG_SCF_FBW7_1 285 292 PF00400 0.720
DEG_SPOP_SBC_1 264 268 PF00917 0.725
DEG_SPOP_SBC_1 325 329 PF00917 0.675
DOC_CKS1_1 286 291 PF01111 0.713
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Homologs

ProteinTaxonomySequence identityCoverage
A4HCZ9 Leishmania braziliensis 64% 100%
A4I0I4 Leishmania infantum 98% 100%
E9AWE6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4QB26 Leishmania major 86% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS