LeishMANIAdb
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Hydrophilic_acylated_surface_protein_a/GeneDB:Lmj F.23.1040/GeneDB:LmjF.23.1082/GeneDB:LmjF.23.1088

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hydrophilic_acylated_surface_protein_a/GeneDB:Lmj F.23.1040/GeneDB:LmjF.23.1082/GeneDB:LmjF.23.1088
Gene product:
hydrophilic acylated surface protein a
Species:
Leishmania donovani
UniProt:
A0A3S7WXQ9_LEIDO
TriTrypDb:
LdCL_230019300 , LDHU3_23.1600
Length:
80

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. no yes: 3
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXQ9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXQ9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 27 31 PF00656 0.656
CLV_PCSK_KEX2_1 15 17 PF00082 0.524
CLV_PCSK_PC1ET2_1 15 17 PF00082 0.524
DOC_USP7_UBL2_3 7 11 PF12436 0.657
LIG_FHA_2 22 28 PF00498 0.659
LIG_TRAF2_1 40 43 PF00917 0.559
MOD_CK1_1 3 9 PF00069 0.647
MOD_CK2_1 6 12 PF00069 0.654
MOD_GlcNHglycan 36 39 PF01048 0.636
MOD_GlcNHglycan 8 11 PF01048 0.629
MOD_GSK3_1 19 26 PF00069 0.742
MOD_NEK2_1 1 6 PF00069 0.765
MOD_NMyristoyl 1 7 PF02799 0.664

Homologs

Protein Taxonomy Sequence identity Coverage
A4I0F2 Leishmania infantum 99% 100%
E9AWB5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 56% 86%
P90552 Leishmania major 72% 91%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS