RNA binding protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), putative

Species:

Leishmania donovani

UniProt:

A0A3S7WXP3_LEIDO

TriTrypDb:

LdBPK_230890.1 , LdCL_230015500 , LDHU3_23.1210

Length:

586

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXP3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXP3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	452	456	PF00656	0.671
CLV_C14_Caspase3-7	76	80	PF00656	0.607
CLV_NRD_NRD_1	286	288	PF00675	0.438
CLV_PCSK_KEX2_1	286	288	PF00082	0.438
CLV_PCSK_SKI1_1	191	195	PF00082	0.516
CLV_PCSK_SKI1_1	205	209	PF00082	0.513
DEG_SCF_FBW7_1	109	115	PF00400	0.579
DEG_SCF_FBW7_1	90	96	PF00400	0.634
DEG_SPOP_SBC_1	467	471	PF00917	0.692
DOC_CKS1_1	109	114	PF01111	0.664
DOC_CKS1_1	133	138	PF01111	0.573
DOC_CKS1_1	310	315	PF01111	0.597
DOC_CKS1_1	90	95	PF01111	0.631
DOC_MAPK_gen_1	251	260	PF00069	0.475
DOC_PP2B_LxvP_1	485	488	PF13499	0.672
DOC_PP4_FxxP_1	582	585	PF00568	0.570
DOC_PP4_MxPP_1	510	513	PF00568	0.604
DOC_USP7_MATH_1	101	105	PF00917	0.553
DOC_USP7_MATH_1	134	138	PF00917	0.572
DOC_USP7_MATH_1	145	149	PF00917	0.595
DOC_USP7_MATH_1	21	25	PF00917	0.550
DOC_USP7_MATH_1	246	250	PF00917	0.497
DOC_USP7_MATH_1	326	330	PF00917	0.567
DOC_USP7_MATH_1	35	39	PF00917	0.640
DOC_USP7_MATH_1	393	397	PF00917	0.615
DOC_USP7_MATH_1	408	412	PF00917	0.603
DOC_USP7_MATH_1	468	472	PF00917	0.647
DOC_USP7_MATH_1	498	502	PF00917	0.661
DOC_USP7_MATH_1	534	538	PF00917	0.612
DOC_USP7_MATH_1	547	551	PF00917	0.627
DOC_USP7_MATH_1	574	578	PF00917	0.557
DOC_USP7_MATH_2	322	328	PF00917	0.537
DOC_USP7_MATH_2	531	537	PF00917	0.613
DOC_WW_Pin1_4	108	113	PF00397	0.686
DOC_WW_Pin1_4	132	137	PF00397	0.572
DOC_WW_Pin1_4	24	29	PF00397	0.599
DOC_WW_Pin1_4	309	314	PF00397	0.615
DOC_WW_Pin1_4	335	340	PF00397	0.650
DOC_WW_Pin1_4	399	404	PF00397	0.600
DOC_WW_Pin1_4	455	460	PF00397	0.663
DOC_WW_Pin1_4	581	586	PF00397	0.572
DOC_WW_Pin1_4	89	94	PF00397	0.686
LIG_14-3-3_CanoR_1	105	110	PF00244	0.636
LIG_14-3-3_CanoR_1	518	523	PF00244	0.576
LIG_APCC_ABBA_1	257	262	PF00400	0.475
LIG_BRCT_BRCA1_1	500	504	PF00533	0.577
LIG_BRCT_BRCA1_1	576	580	PF00533	0.633
LIG_BRCT_BRCA1_1	60	64	PF00533	0.551
LIG_FHA_1	25	31	PF00498	0.520
LIG_FHA_1	280	286	PF00498	0.529
LIG_FHA_1	400	406	PF00498	0.628
LIG_FHA_1	67	73	PF00498	0.625
LIG_LIR_Apic_2	128	134	PF02991	0.573
LIG_LIR_Nem_3	11	16	PF02991	0.564
LIG_LIR_Nem_3	128	133	PF02991	0.593
LIG_LIR_Nem_3	577	583	PF02991	0.560
LIG_LIR_Nem_3	61	66	PF02991	0.630
LIG_MLH1_MIPbox_1	60	64	PF16413	0.627
LIG_Pex14_2	62	66	PF04695	0.629
LIG_PTAP_UEV_1	135	140	PF05743	0.577
LIG_SH2_CRK	131	135	PF00017	0.608
LIG_SH2_GRB2like	86	89	PF00017	0.676
LIG_SH2_STAP1	86	90	PF00017	0.677
LIG_SH2_STAT5	129	132	PF00017	0.571
LIG_SH2_STAT5	566	569	PF00017	0.583
LIG_SH2_STAT5	581	584	PF00017	0.557
LIG_SH2_STAT5	63	66	PF00017	0.632
LIG_SH3_2	136	141	PF14604	0.583
LIG_SH3_2	513	518	PF14604	0.619
LIG_SH3_3	133	139	PF00018	0.573
LIG_SH3_3	165	171	PF00018	0.670
LIG_SH3_3	293	299	PF00018	0.539
LIG_SH3_3	308	314	PF00018	0.615
LIG_SH3_3	336	342	PF00018	0.552
LIG_SH3_3	364	370	PF00018	0.624
LIG_SH3_3	437	443	PF00018	0.698
LIG_SH3_3	44	50	PF00018	0.584
LIG_SH3_3	503	509	PF00018	0.625
LIG_SH3_3	510	516	PF00018	0.610
LIG_SH3_3	87	93	PF00018	0.595
LIG_SUMO_SIM_anti_2	192	198	PF11976	0.567
LIG_WRC_WIRS_1	63	68	PF05994	0.628
MOD_CK1_1	108	114	PF00069	0.661
MOD_CK1_1	148	154	PF00069	0.656
MOD_CK1_1	24	30	PF00069	0.696
MOD_CK1_1	265	271	PF00069	0.461
MOD_CK1_1	378	384	PF00069	0.630
MOD_CK1_1	38	44	PF00069	0.702
MOD_CK1_1	392	398	PF00069	0.584
MOD_CK1_1	401	407	PF00069	0.582
MOD_CK1_1	409	415	PF00069	0.595
MOD_CK1_1	444	450	PF00069	0.769
MOD_CK1_1	466	472	PF00069	0.808
MOD_CK1_1	521	527	PF00069	0.689
MOD_CK1_1	554	560	PF00069	0.644
MOD_CK1_1	9	15	PF00069	0.538
MOD_GlcNHglycan	117	120	PF01048	0.618
MOD_GlcNHglycan	136	139	PF01048	0.573
MOD_GlcNHglycan	147	150	PF01048	0.592
MOD_GlcNHglycan	17	20	PF01048	0.611
MOD_GlcNHglycan	215	218	PF01048	0.293
MOD_GlcNHglycan	224	227	PF01048	0.284
MOD_GlcNHglycan	23	26	PF01048	0.662
MOD_GlcNHglycan	264	267	PF01048	0.275
MOD_GlcNHglycan	289	293	PF01048	0.496
MOD_GlcNHglycan	307	310	PF01048	0.615
MOD_GlcNHglycan	326	329	PF01048	0.526
MOD_GlcNHglycan	354	357	PF01048	0.574
MOD_GlcNHglycan	377	380	PF01048	0.604
MOD_GlcNHglycan	391	394	PF01048	0.591
MOD_GlcNHglycan	433	436	PF01048	0.692
MOD_GlcNHglycan	470	473	PF01048	0.697
MOD_GlcNHglycan	476	479	PF01048	0.593
MOD_GlcNHglycan	536	539	PF01048	0.694
MOD_GlcNHglycan	545	548	PF01048	0.567
MOD_GlcNHglycan	549	552	PF01048	0.552
MOD_GlcNHglycan	553	556	PF01048	0.500
MOD_GlcNHglycan	8	11	PF01048	0.537
MOD_GlcNHglycan	95	98	PF01048	0.632
MOD_GSK3_1	101	108	PF00069	0.586
MOD_GSK3_1	111	118	PF00069	0.508
MOD_GSK3_1	144	151	PF00069	0.611
MOD_GSK3_1	159	166	PF00069	0.643
MOD_GSK3_1	20	27	PF00069	0.696
MOD_GSK3_1	265	272	PF00069	0.487
MOD_GSK3_1	305	312	PF00069	0.615
MOD_GSK3_1	320	327	PF00069	0.604
MOD_GSK3_1	340	347	PF00069	0.600
MOD_GSK3_1	35	42	PF00069	0.685
MOD_GSK3_1	357	364	PF00069	0.614
MOD_GSK3_1	389	396	PF00069	0.680
MOD_GSK3_1	397	404	PF00069	0.577
MOD_GSK3_1	408	415	PF00069	0.595
MOD_GSK3_1	446	453	PF00069	0.647
MOD_GSK3_1	458	465	PF00069	0.624
MOD_GSK3_1	543	550	PF00069	0.696
MOD_GSK3_1	58	65	PF00069	0.577
MOD_GSK3_1	82	89	PF00069	0.642
MOD_GSK3_1	91	98	PF00069	0.630
MOD_N-GLC_1	151	156	PF02516	0.589
MOD_N-GLC_1	303	308	PF02516	0.612
MOD_N-GLC_1	389	394	PF02516	0.677
MOD_N-GLC_1	409	414	PF02516	0.467
MOD_N-GLC_1	572	577	PF02516	0.589
MOD_N-GLC_1	80	85	PF02516	0.665
MOD_N-GLC_2	267	269	PF02516	0.382
MOD_NEK2_1	361	366	PF00069	0.537
MOD_NEK2_1	39	44	PF00069	0.617
MOD_NEK2_1	397	402	PF00069	0.607
MOD_NEK2_1	413	418	PF00069	0.678
MOD_NEK2_1	446	451	PF00069	0.718
MOD_NEK2_1	476	481	PF00069	0.653
MOD_NEK2_1	572	577	PF00069	0.495
MOD_NEK2_1	62	67	PF00069	0.628
MOD_NEK2_1	82	87	PF00069	0.467
MOD_NEK2_1	95	100	PF00069	0.607
MOD_NEK2_2	345	350	PF00069	0.606
MOD_NEK2_2	58	63	PF00069	0.629
MOD_PIKK_1	298	304	PF00454	0.593
MOD_PIKK_1	476	482	PF00454	0.583
MOD_PK_1	518	524	PF00069	0.621
MOD_PKA_2	163	169	PF00069	0.685
MOD_PKA_2	222	228	PF00069	0.478
MOD_PKB_1	303	311	PF00069	0.613
MOD_Plk_1	409	415	PF00069	0.622
MOD_Plk_4	370	376	PF00069	0.640
MOD_Plk_4	401	407	PF00069	0.626
MOD_Plk_4	409	415	PF00069	0.595
MOD_Plk_4	441	447	PF00069	0.627
MOD_Plk_4	49	55	PF00069	0.628
MOD_Plk_4	58	64	PF00069	0.527
MOD_ProDKin_1	108	114	PF00069	0.686
MOD_ProDKin_1	132	138	PF00069	0.572
MOD_ProDKin_1	24	30	PF00069	0.600
MOD_ProDKin_1	309	315	PF00069	0.618
MOD_ProDKin_1	335	341	PF00069	0.643
MOD_ProDKin_1	399	405	PF00069	0.601
MOD_ProDKin_1	455	461	PF00069	0.663
MOD_ProDKin_1	89	95	PF00069	0.686
TRG_ENDOCYTIC_2	529	532	PF00928	0.584
TRG_ENDOCYTIC_2	63	66	PF00928	0.632
TRG_ER_diArg_1	285	287	PF00400	0.433

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEZ5	Leptomonas seymouri	47%	89%
A4HCU2	Leishmania braziliensis	77%	100%
A4I0C3	Leishmania infantum	100%	100%
E9AW87	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QB91	Leishmania major	94%	100%