Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WXL8_LEIDO

TriTrypDb:

LdBPK_230780.1 , LdCL_230014300 , LDHU3_23.1070

Length:

279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXL8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXL8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	19	23	PF00656	0.402
CLV_PCSK_KEX2_1	160	162	PF00082	0.526
CLV_PCSK_PC1ET2_1	160	162	PF00082	0.521
CLV_PCSK_SKI1_1	157	161	PF00082	0.406
CLV_PCSK_SKI1_1	61	65	PF00082	0.374
CLV_PCSK_SKI1_1	71	75	PF00082	0.454
CLV_PCSK_SKI1_1	77	81	PF00082	0.484
DEG_SPOP_SBC_1	261	265	PF00917	0.573
DOC_CYCLIN_RxL_1	157	167	PF00134	0.417
DOC_CYCLIN_RxL_1	68	78	PF00134	0.406
DOC_MAPK_gen_1	244	252	PF00069	0.519
DOC_MAPK_MEF2A_6	11	20	PF00069	0.357
DOC_PP1_RVXF_1	69	75	PF00149	0.404
DOC_PP2B_LxvP_1	250	253	PF13499	0.575
DOC_PP2B_LxvP_1	32	35	PF13499	0.518
DOC_PP2B_LxvP_1	73	76	PF13499	0.435
DOC_USP7_MATH_1	136	140	PF00917	0.565
DOC_USP7_MATH_1	144	148	PF00917	0.492
DOC_USP7_MATH_1	204	208	PF00917	0.595
DOC_USP7_MATH_1	259	263	PF00917	0.573
DOC_USP7_MATH_1	45	49	PF00917	0.545
DOC_WW_Pin1_4	214	219	PF00397	0.622
DOC_WW_Pin1_4	268	273	PF00397	0.566
LIG_14-3-3_CanoR_1	120	129	PF00244	0.477
LIG_APCC_ABBA_1	14	19	PF00400	0.342
LIG_BIR_II_1	1	5	PF00653	0.476
LIG_FHA_1	151	157	PF00498	0.408
LIG_FHA_1	22	28	PF00498	0.422
LIG_FHA_1	76	82	PF00498	0.407
LIG_FHA_2	186	192	PF00498	0.600
LIG_FHA_2	53	59	PF00498	0.414
LIG_GBD_Chelix_1	155	163	PF00786	0.399
LIG_LIR_Nem_3	150	155	PF02991	0.414
LIG_LIR_Nem_3	82	86	PF02991	0.355
LIG_NRBOX	158	164	PF00104	0.409
LIG_PCNA_yPIPBox_3	231	244	PF02747	0.446
LIG_PCNA_yPIPBox_3	4	17	PF02747	0.402
LIG_PTB_Apo_2	189	196	PF02174	0.578
LIG_SH2_CRK	152	156	PF00017	0.404
LIG_SH2_STAT5	152	155	PF00017	0.405
LIG_SH2_STAT5	197	200	PF00017	0.591
LIG_SH2_STAT5	86	89	PF00017	0.378
LIG_SH3_3	27	33	PF00018	0.481
LIG_SUMO_SIM_anti_2	186	191	PF11976	0.564
LIG_SUMO_SIM_anti_2	55	62	PF11976	0.597
LIG_SUMO_SIM_par_1	248	255	PF11976	0.564
LIG_TYR_ITSM	148	155	PF00017	0.434
LIG_WRC_WIRS_1	80	85	PF05994	0.359
MOD_CDC14_SPxK_1	217	220	PF00782	0.612
MOD_CDK_SPxK_1	214	220	PF00069	0.613
MOD_CK1_1	139	145	PF00069	0.577
MOD_CK1_1	147	153	PF00069	0.422
MOD_CK1_1	262	268	PF00069	0.579
MOD_CK2_1	185	191	PF00069	0.617
MOD_GlcNHglycan	107	111	PF01048	0.465
MOD_GlcNHglycan	141	144	PF01048	0.583
MOD_GlcNHglycan	183	186	PF01048	0.666
MOD_GlcNHglycan	214	217	PF01048	0.673
MOD_GlcNHglycan	266	269	PF01048	0.581
MOD_GlcNHglycan	36	39	PF01048	0.533
MOD_GlcNHglycan	47	50	PF01048	0.485
MOD_GSK3_1	139	146	PF00069	0.572
MOD_GSK3_1	179	186	PF00069	0.654
MOD_GSK3_1	191	198	PF00069	0.741
MOD_GSK3_1	21	28	PF00069	0.421
MOD_GSK3_1	212	219	PF00069	0.615
MOD_GSK3_1	248	255	PF00069	0.564
MOD_GSK3_1	260	267	PF00069	0.517
MOD_GSK3_1	75	82	PF00069	0.405
MOD_N-GLC_1	136	141	PF02516	0.571
MOD_N-GLC_1	191	196	PF02516	0.581
MOD_N-GLC_2	138	140	PF02516	0.570
MOD_NEK2_1	181	186	PF00069	0.561
MOD_NEK2_1	190	195	PF00069	0.533
MOD_NEK2_2	21	26	PF00069	0.413
MOD_NEK2_2	79	84	PF00069	0.376
MOD_Plk_1	106	112	PF00069	0.470
MOD_Plk_1	190	196	PF00069	0.580
MOD_Plk_1	21	27	PF00069	0.415
MOD_Plk_4	147	153	PF00069	0.462
MOD_Plk_4	185	191	PF00069	0.563
MOD_ProDKin_1	214	220	PF00069	0.623
MOD_ProDKin_1	268	274	PF00069	0.565
TRG_DiLeu_BaLyEn_6	158	163	PF01217	0.402
TRG_ENDOCYTIC_2	152	155	PF00928	0.405
TRG_ER_diArg_1	243	246	PF00400	0.447
TRG_Pf-PMV_PEXEL_1	160	164	PF00026	0.423

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I0B2	Leishmania infantum	100%	100%