Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WXJ3_LEIDO

TriTrypDb:

LdBPK_230520.1 , LdCL_230010600 , LDHU3_23.0730

Length:

1417

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXJ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1279	1283	PF00656	0.586
CLV_C14_Caspase3-7	203	207	PF00656	0.537
CLV_C14_Caspase3-7	828	832	PF00656	0.494
CLV_NRD_NRD_1	26	28	PF00675	0.577
CLV_NRD_NRD_1	35	37	PF00675	0.539
CLV_NRD_NRD_1	400	402	PF00675	0.543
CLV_NRD_NRD_1	486	488	PF00675	0.663
CLV_NRD_NRD_1	622	624	PF00675	0.570
CLV_NRD_NRD_1	672	674	PF00675	0.507
CLV_NRD_NRD_1	733	735	PF00675	0.541
CLV_NRD_NRD_1	854	856	PF00675	0.635
CLV_NRD_NRD_1	873	875	PF00675	0.343
CLV_NRD_NRD_1	919	921	PF00675	0.470
CLV_NRD_NRD_1	96	98	PF00675	0.616
CLV_PCSK_FUR_1	32	36	PF00082	0.615
CLV_PCSK_FUR_1	620	624	PF00082	0.569
CLV_PCSK_KEX2_1	1045	1047	PF00082	0.485
CLV_PCSK_KEX2_1	140	142	PF00082	0.502
CLV_PCSK_KEX2_1	26	28	PF00082	0.573
CLV_PCSK_KEX2_1	34	36	PF00082	0.541
CLV_PCSK_KEX2_1	400	402	PF00082	0.543
CLV_PCSK_KEX2_1	622	624	PF00082	0.570
CLV_PCSK_KEX2_1	733	735	PF00082	0.541
CLV_PCSK_KEX2_1	838	840	PF00082	0.539
CLV_PCSK_KEX2_1	856	858	PF00082	0.474
CLV_PCSK_KEX2_1	862	864	PF00082	0.520
CLV_PCSK_KEX2_1	919	921	PF00082	0.470
CLV_PCSK_KEX2_1	96	98	PF00082	0.630
CLV_PCSK_PC1ET2_1	1045	1047	PF00082	0.485
CLV_PCSK_PC1ET2_1	140	142	PF00082	0.502
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.617
CLV_PCSK_PC1ET2_1	838	840	PF00082	0.539
CLV_PCSK_PC1ET2_1	856	858	PF00082	0.474
CLV_PCSK_PC1ET2_1	862	864	PF00082	0.486
CLV_PCSK_SKI1_1	1027	1031	PF00082	0.563
CLV_PCSK_SKI1_1	1045	1049	PF00082	0.368
CLV_PCSK_SKI1_1	128	132	PF00082	0.543
CLV_PCSK_SKI1_1	394	398	PF00082	0.504
CLV_PCSK_SKI1_1	708	712	PF00082	0.605
DEG_APCC_DBOX_1	1069	1077	PF00400	0.442
DEG_APCC_DBOX_1	1248	1256	PF00400	0.464
DEG_APCC_DBOX_1	127	135	PF00400	0.549
DEG_APCC_DBOX_1	475	483	PF00400	0.457
DEG_APCC_DBOX_1	559	567	PF00400	0.358
DEG_COP1_1	1203	1212	PF00400	0.450
DEG_Nend_UBRbox_2	1	3	PF02207	0.463
DEG_SCF_FBW7_2	762	769	PF00400	0.562
DEG_SPOP_SBC_1	979	983	PF00917	0.627
DOC_CYCLIN_yCln2_LP_2	897	903	PF00134	0.469
DOC_MAPK_DCC_7	47	56	PF00069	0.513
DOC_MAPK_gen_1	1045	1053	PF00069	0.480
DOC_MAPK_gen_1	862	869	PF00069	0.473
DOC_MAPK_gen_1	919	927	PF00069	0.551
DOC_MAPK_MEF2A_6	1046	1055	PF00069	0.479
DOC_MAPK_MEF2A_6	128	136	PF00069	0.484
DOC_MAPK_MEF2A_6	47	56	PF00069	0.573
DOC_MAPK_MEF2A_6	862	869	PF00069	0.514
DOC_MAPK_NFAT4_5	862	870	PF00069	0.511
DOC_MIT_MIM_1	308	318	PF04212	0.453
DOC_PP2B_LxvP_1	1207	1210	PF13499	0.475
DOC_PP2B_LxvP_1	1394	1397	PF13499	0.638
DOC_PP2B_LxvP_1	61	64	PF13499	0.522
DOC_PP4_FxxP_1	217	220	PF00568	0.499
DOC_USP7_MATH_1	1064	1068	PF00917	0.493
DOC_USP7_MATH_1	113	117	PF00917	0.494
DOC_USP7_MATH_1	1234	1238	PF00917	0.542
DOC_USP7_MATH_1	1303	1307	PF00917	0.488
DOC_USP7_MATH_1	1397	1401	PF00917	0.588
DOC_USP7_MATH_1	247	251	PF00917	0.517
DOC_USP7_MATH_1	303	307	PF00917	0.447
DOC_USP7_MATH_1	317	321	PF00917	0.435
DOC_USP7_MATH_1	333	337	PF00917	0.479
DOC_USP7_MATH_1	376	380	PF00917	0.539
DOC_USP7_MATH_1	384	388	PF00917	0.448
DOC_USP7_MATH_1	613	617	PF00917	0.556
DOC_USP7_MATH_1	789	793	PF00917	0.597
DOC_USP7_MATH_1	832	836	PF00917	0.478
DOC_USP7_MATH_1	909	913	PF00917	0.452
DOC_USP7_MATH_1	95	99	PF00917	0.559
DOC_USP7_MATH_1	978	982	PF00917	0.579
DOC_USP7_MATH_2	771	777	PF00917	0.633
DOC_WW_Pin1_4	115	120	PF00397	0.678
DOC_WW_Pin1_4	41	46	PF00397	0.589
DOC_WW_Pin1_4	762	767	PF00397	0.541
DOC_WW_Pin1_4	774	779	PF00397	0.692
DOC_WW_Pin1_4	79	84	PF00397	0.717
DOC_WW_Pin1_4	896	901	PF00397	0.448
LIG_14-3-3_CanoR_1	1027	1037	PF00244	0.533
LIG_14-3-3_CanoR_1	1046	1053	PF00244	0.378
LIG_14-3-3_CanoR_1	11	20	PF00244	0.546
LIG_14-3-3_CanoR_1	151	159	PF00244	0.541
LIG_14-3-3_CanoR_1	275	280	PF00244	0.503
LIG_14-3-3_CanoR_1	353	361	PF00244	0.476
LIG_14-3-3_CanoR_1	394	399	PF00244	0.521
LIG_14-3-3_CanoR_1	540	548	PF00244	0.387
LIG_14-3-3_CanoR_1	585	593	PF00244	0.609
LIG_14-3-3_CanoR_1	620	628	PF00244	0.566
LIG_14-3-3_CanoR_1	684	690	PF00244	0.475
LIG_14-3-3_CanoR_1	726	732	PF00244	0.578
LIG_14-3-3_CanoR_1	874	883	PF00244	0.622
LIG_Actin_WH2_2	1030	1047	PF00022	0.443
LIG_Actin_WH2_2	159	176	PF00022	0.486
LIG_Actin_WH2_2	391	409	PF00022	0.489
LIG_APCC_ABBA_1	1216	1221	PF00400	0.443
LIG_BIR_III_4	375	379	PF00653	0.532
LIG_BRCT_BRCA1_1	213	217	PF00533	0.514
LIG_CaM_IQ_9	1128	1144	PF13499	0.580
LIG_Clathr_ClatBox_1	131	135	PF01394	0.556
LIG_CtBP_PxDLS_1	1052	1056	PF00389	0.476
LIG_FHA_1	1029	1035	PF00498	0.490
LIG_FHA_1	1036	1042	PF00498	0.544
LIG_FHA_1	1046	1052	PF00498	0.386
LIG_FHA_1	1291	1297	PF00498	0.490
LIG_FHA_1	1333	1339	PF00498	0.487
LIG_FHA_1	1353	1359	PF00498	0.308
LIG_FHA_1	151	157	PF00498	0.495
LIG_FHA_1	470	476	PF00498	0.474
LIG_FHA_1	654	660	PF00498	0.478
LIG_FHA_1	688	694	PF00498	0.468
LIG_FHA_1	705	711	PF00498	0.532
LIG_FHA_1	775	781	PF00498	0.712
LIG_FHA_1	831	837	PF00498	0.517
LIG_FHA_1	930	936	PF00498	0.519
LIG_FHA_1	946	952	PF00498	0.362
LIG_FHA_2	1160	1166	PF00498	0.598
LIG_FHA_2	150	156	PF00498	0.547
LIG_FHA_2	166	172	PF00498	0.529
LIG_FHA_2	201	207	PF00498	0.599
LIG_FHA_2	320	326	PF00498	0.459
LIG_FHA_2	523	529	PF00498	0.539
LIG_FHA_2	597	603	PF00498	0.614
LIG_FHA_2	826	832	PF00498	0.500
LIG_FHA_2	85	91	PF00498	0.707
LIG_GBD_Chelix_1	1004	1012	PF00786	0.521
LIG_GBD_Chelix_1	917	925	PF00786	0.471
LIG_LIR_Apic_2	214	220	PF02991	0.506
LIG_LIR_LC3C_4	1204	1209	PF02991	0.477
LIG_LIR_Nem_3	720	725	PF02991	0.492
LIG_NRBOX	1310	1316	PF00104	0.432
LIG_PCNA_yPIPBox_3	272	280	PF02747	0.444
LIG_PTAP_UEV_1	90	95	PF05743	0.544
LIG_SH2_STAT5	1079	1082	PF00017	0.444
LIG_SH2_STAT5	40	43	PF00017	0.589
LIG_SH3_2	91	96	PF14604	0.617
LIG_SH3_3	107	113	PF00018	0.480
LIG_SH3_3	62	68	PF00018	0.513
LIG_SH3_3	764	770	PF00018	0.606
LIG_SH3_3	78	84	PF00018	0.598
LIG_SH3_3	88	94	PF00018	0.643
LIG_SUMO_SIM_anti_2	1082	1089	PF11976	0.438
LIG_SUMO_SIM_anti_2	1334	1340	PF11976	0.491
LIG_SUMO_SIM_anti_2	1355	1360	PF11976	0.505
LIG_SUMO_SIM_anti_2	948	953	PF11976	0.472
LIG_SUMO_SIM_par_1	1082	1089	PF11976	0.487
LIG_SUMO_SIM_par_1	130	135	PF11976	0.478
LIG_SUMO_SIM_par_1	1334	1340	PF11976	0.491
LIG_SUMO_SIM_par_1	446	452	PF11976	0.576
LIG_SUMO_SIM_par_1	759	765	PF11976	0.556
LIG_TRAF2_1	1011	1014	PF00917	0.424
LIG_TRAF2_1	1147	1150	PF00917	0.505
LIG_TRAF2_1	388	391	PF00917	0.475
LIG_TRAF2_1	677	680	PF00917	0.567
LIG_TRAF2_1	735	738	PF00917	0.614
LIG_TRAF2_1	817	820	PF00917	0.474
LIG_TRAF2_1	997	1000	PF00917	0.569
LIG_UBA3_1	131	138	PF00899	0.482
LIG_WW_2	65	68	PF00397	0.510
MOD_CDK_SPxK_1	41	47	PF00069	0.553
MOD_CDK_SPxK_1	762	768	PF00069	0.584
MOD_CK1_1	1089	1095	PF00069	0.538
MOD_CK1_1	1236	1242	PF00069	0.486
MOD_CK1_1	1297	1303	PF00069	0.404
MOD_CK1_1	1398	1404	PF00069	0.507
MOD_CK1_1	1406	1412	PF00069	0.488
MOD_CK1_1	161	167	PF00069	0.554
MOD_CK1_1	200	206	PF00069	0.565
MOD_CK1_1	227	233	PF00069	0.504
MOD_CK1_1	290	296	PF00069	0.544
MOD_CK1_1	374	380	PF00069	0.593
MOD_CK1_1	522	528	PF00069	0.539
MOD_CK1_1	547	553	PF00069	0.488
MOD_CK1_1	687	693	PF00069	0.450
MOD_CK1_1	882	888	PF00069	0.582
MOD_CK1_1	981	987	PF00069	0.494
MOD_CK2_1	1404	1410	PF00069	0.570
MOD_CK2_1	141	147	PF00069	0.566
MOD_CK2_1	149	155	PF00069	0.502
MOD_CK2_1	165	171	PF00069	0.504
MOD_CK2_1	331	337	PF00069	0.481
MOD_CK2_1	385	391	PF00069	0.554
MOD_CK2_1	596	602	PF00069	0.470
MOD_CK2_1	613	619	PF00069	0.500
MOD_CK2_1	789	795	PF00069	0.614
MOD_CK2_1	979	985	PF00069	0.657
MOD_Cter_Amidation	853	856	PF01082	0.531
MOD_GlcNHglycan	102	105	PF01048	0.660
MOD_GlcNHglycan	1062	1065	PF01048	0.517
MOD_GlcNHglycan	1091	1094	PF01048	0.462
MOD_GlcNHglycan	1117	1122	PF01048	0.533
MOD_GlcNHglycan	1191	1194	PF01048	0.468
MOD_GlcNHglycan	1380	1383	PF01048	0.539
MOD_GlcNHglycan	1403	1406	PF01048	0.504
MOD_GlcNHglycan	198	202	PF01048	0.646
MOD_GlcNHglycan	213	216	PF01048	0.422
MOD_GlcNHglycan	305	308	PF01048	0.502
MOD_GlcNHglycan	315	318	PF01048	0.398
MOD_GlcNHglycan	333	336	PF01048	0.479
MOD_GlcNHglycan	375	379	PF01048	0.512
MOD_GlcNHglycan	521	524	PF01048	0.513
MOD_GlcNHglycan	791	794	PF01048	0.657
MOD_GlcNHglycan	886	889	PF01048	0.515
MOD_GlcNHglycan	90	94	PF01048	0.578
MOD_GlcNHglycan	975	978	PF01048	0.578
MOD_GlcNHglycan	987	990	PF01048	0.536
MOD_GSK3_1	1	8	PF00069	0.515
MOD_GSK3_1	1028	1035	PF00069	0.473
MOD_GSK3_1	1060	1067	PF00069	0.445
MOD_GSK3_1	1234	1241	PF00069	0.463
MOD_GSK3_1	1290	1297	PF00069	0.562
MOD_GSK3_1	1395	1402	PF00069	0.541
MOD_GSK3_1	150	157	PF00069	0.577
MOD_GSK3_1	161	168	PF00069	0.478
MOD_GSK3_1	189	196	PF00069	0.576
MOD_GSK3_1	197	204	PF00069	0.556
MOD_GSK3_1	207	214	PF00069	0.398
MOD_GSK3_1	271	278	PF00069	0.510
MOD_GSK3_1	313	320	PF00069	0.430
MOD_GSK3_1	331	338	PF00069	0.481
MOD_GSK3_1	370	377	PF00069	0.508
MOD_GSK3_1	460	467	PF00069	0.538
MOD_GSK3_1	540	547	PF00069	0.531
MOD_GSK3_1	779	786	PF00069	0.762
MOD_GSK3_1	85	92	PF00069	0.624
MOD_GSK3_1	870	877	PF00069	0.511
MOD_GSK3_1	9	16	PF00069	0.506
MOD_GSK3_1	95	102	PF00069	0.619
MOD_GSK3_1	952	959	PF00069	0.443
MOD_GSK3_1	981	988	PF00069	0.745
MOD_N-GLC_1	1089	1094	PF02516	0.537
MOD_N-GLC_1	1195	1200	PF02516	0.447
MOD_N-GLC_1	685	690	PF02516	0.557
MOD_N-GLC_1	909	914	PF02516	0.454
MOD_NEK2_1	1	6	PF00069	0.566
MOD_NEK2_1	100	105	PF00069	0.618
MOD_NEK2_1	1134	1139	PF00069	0.442
MOD_NEK2_1	1359	1364	PF00069	0.502
MOD_NEK2_1	173	178	PF00069	0.516
MOD_NEK2_1	225	230	PF00069	0.455
MOD_NEK2_1	313	318	PF00069	0.453
MOD_NEK2_1	385	390	PF00069	0.508
MOD_NEK2_1	596	601	PF00069	0.643
MOD_NEK2_1	685	690	PF00069	0.525
MOD_NEK2_1	788	793	PF00069	0.640
MOD_NEK2_1	803	808	PF00069	0.446
MOD_NEK2_1	952	957	PF00069	0.442
MOD_PIKK_1	1297	1303	PF00454	0.404
MOD_PIKK_1	161	167	PF00454	0.482
MOD_PIKK_1	189	195	PF00454	0.467
MOD_PIKK_1	290	296	PF00454	0.544
MOD_PIKK_1	319	325	PF00454	0.515
MOD_PIKK_1	385	391	PF00454	0.554
MOD_PIKK_1	486	492	PF00454	0.546
MOD_PIKK_1	575	581	PF00454	0.518
MOD_PIKK_1	687	693	PF00454	0.450
MOD_PIKK_1	724	730	PF00454	0.584
MOD_PIKK_1	882	888	PF00454	0.445
MOD_PIKK_1	956	962	PF00454	0.652
MOD_PK_1	141	147	PF00069	0.534
MOD_PK_1	275	281	PF00069	0.433
MOD_PKA_1	1045	1051	PF00069	0.482
MOD_PKA_1	874	880	PF00069	0.481
MOD_PKA_2	1045	1051	PF00069	0.490
MOD_PKA_2	13	19	PF00069	0.549
MOD_PKA_2	1398	1404	PF00069	0.601
MOD_PKA_2	150	156	PF00069	0.527
MOD_PKA_2	218	224	PF00069	0.586
MOD_PKA_2	271	277	PF00069	0.512
MOD_PKA_2	303	309	PF00069	0.442
MOD_PKA_2	313	319	PF00069	0.440
MOD_PKA_2	486	492	PF00069	0.491
MOD_PKA_2	621	627	PF00069	0.541
MOD_PKA_2	704	710	PF00069	0.566
MOD_PKA_2	95	101	PF00069	0.626
MOD_PKB_1	682	690	PF00069	0.509
MOD_PKB_1	97	105	PF00069	0.636
MOD_Plk_1	1	7	PF00069	0.538
MOD_Plk_1	1342	1348	PF00069	0.558
MOD_Plk_1	16	22	PF00069	0.503
MOD_Plk_1	239	245	PF00069	0.599
MOD_Plk_1	290	296	PF00069	0.544
MOD_Plk_1	514	520	PF00069	0.484
MOD_Plk_1	543	549	PF00069	0.491
MOD_Plk_1	59	65	PF00069	0.533
MOD_Plk_1	631	637	PF00069	0.532
MOD_Plk_1	685	691	PF00069	0.557
MOD_Plk_1	9	15	PF00069	0.487
MOD_Plk_1	909	915	PF00069	0.504
MOD_Plk_4	1359	1365	PF00069	0.501
MOD_Plk_4	1390	1396	PF00069	0.637
MOD_Plk_4	275	281	PF00069	0.469
MOD_Plk_4	433	439	PF00069	0.406
MOD_Plk_4	757	763	PF00069	0.522
MOD_ProDKin_1	115	121	PF00069	0.675
MOD_ProDKin_1	41	47	PF00069	0.586
MOD_ProDKin_1	762	768	PF00069	0.544
MOD_ProDKin_1	774	780	PF00069	0.692
MOD_ProDKin_1	79	85	PF00069	0.721
MOD_ProDKin_1	896	902	PF00069	0.446
MOD_SUMO_for_1	284	287	PF00179	0.443
MOD_SUMO_rev_2	1040	1047	PF00179	0.448
MOD_SUMO_rev_2	562	571	PF00179	0.418
TRG_DiLeu_BaEn_1	158	163	PF01217	0.727
TRG_DiLeu_BaLyEn_6	569	574	PF01217	0.428
TRG_DiLeu_BaLyEn_6	96	101	PF01217	0.599
TRG_ENDOCYTIC_2	355	358	PF00928	0.413
TRG_ENDOCYTIC_2	722	725	PF00928	0.480
TRG_ER_diArg_1	1100	1103	PF00400	0.582
TRG_ER_diArg_1	35	37	PF00400	0.588
TRG_ER_diArg_1	400	402	PF00400	0.543
TRG_ER_diArg_1	609	612	PF00400	0.507
TRG_ER_diArg_1	620	623	PF00400	0.493
TRG_ER_diArg_1	642	645	PF00400	0.460
TRG_ER_diArg_1	682	685	PF00400	0.509
TRG_ER_diArg_1	919	922	PF00400	0.545
TRG_ER_diArg_1	96	99	PF00400	0.622
TRG_NES_CRM1_1	1043	1054	PF08389	0.398
TRG_NES_CRM1_1	915	930	PF08389	0.550
TRG_NES_CRM1_1	961	973	PF08389	0.528
TRG_NES_CRM1_1	999	1014	PF08389	0.561
TRG_Pf-PMV_PEXEL_1	1136	1140	PF00026	0.496
TRG_Pf-PMV_PEXEL_1	160	165	PF00026	0.545
TRG_Pf-PMV_PEXEL_1	296	301	PF00026	0.496
TRG_Pf-PMV_PEXEL_1	400	404	PF00026	0.562
TRG_Pf-PMV_PEXEL_1	411	415	PF00026	0.405
TRG_Pf-PMV_PEXEL_1	572	576	PF00026	0.461
TRG_Pf-PMV_PEXEL_1	594	598	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	719	723	PF00026	0.487
TRG_Pf-PMV_PEXEL_1	919	923	PF00026	0.538

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IH86	Leptomonas seymouri	44%	98%
A4HCR2	Leishmania braziliensis	71%	99%
A4I087	Leishmania infantum	100%	100%
E9AW51	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QBC6	Leishmania major	89%	98%