Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WXG0_LEIDO

TriTrypDb:

LdBPK_230070.1 , LdCL_230005600 , LDHU3_23.0090

Length:

173

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WXG0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WXG0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	106	108	PF00675	0.536
CLV_NRD_NRD_1	114	116	PF00675	0.562
CLV_NRD_NRD_1	138	140	PF00675	0.655
CLV_NRD_NRD_1	7	9	PF00675	0.529
CLV_NRD_NRD_1	78	80	PF00675	0.431
CLV_NRD_NRD_1	82	84	PF00675	0.447
CLV_PCSK_FUR_1	76	80	PF00082	0.435
CLV_PCSK_KEX2_1	113	115	PF00082	0.569
CLV_PCSK_KEX2_1	138	140	PF00082	0.655
CLV_PCSK_KEX2_1	7	9	PF00082	0.529
CLV_PCSK_KEX2_1	78	80	PF00082	0.429
CLV_PCSK_KEX2_1	82	84	PF00082	0.460
CLV_PCSK_PC1ET2_1	113	115	PF00082	0.569
CLV_PCSK_PC7_1	3	9	PF00082	0.533
CLV_PCSK_PC7_1	78	84	PF00082	0.477
CLV_PCSK_SKI1_1	14	18	PF00082	0.525
CLV_PCSK_SKI1_1	19	23	PF00082	0.458
CLV_PCSK_SKI1_1	83	87	PF00082	0.450
DEG_Nend_Nbox_1	1	3	PF02207	0.530
DEG_SPOP_SBC_1	51	55	PF00917	0.416
DOC_MAPK_gen_1	14	22	PF00069	0.546
DOC_MAPK_MEF2A_6	163	170	PF00069	0.653
DOC_MAPK_NFAT4_5	163	171	PF00069	0.585
DOC_USP7_MATH_1	147	151	PF00917	0.596
DOC_USP7_MATH_1	45	49	PF00917	0.506
DOC_USP7_MATH_1	52	56	PF00917	0.550
DOC_WW_Pin1_4	127	132	PF00397	0.747
LIG_14-3-3_CanoR_1	139	145	PF00244	0.744
LIG_Actin_WH2_2	13	28	PF00022	0.434
LIG_Actin_WH2_2	64	80	PF00022	0.506
LIG_BRCT_BRCA1_1	150	154	PF00533	0.704
LIG_CtBP_PxDLS_1	126	130	PF00389	0.571
LIG_FHA_1	150	156	PF00498	0.692
LIG_SH3_3	139	145	PF00018	0.708
LIG_SUMO_SIM_par_1	125	130	PF11976	0.616
MOD_CK2_1	127	133	PF00069	0.686
MOD_CK2_1	147	153	PF00069	0.595
MOD_Cter_Amidation	136	139	PF01082	0.525
MOD_GlcNHglycan	120	123	PF01048	0.561
MOD_GlcNHglycan	47	50	PF01048	0.535
MOD_NEK2_1	25	30	PF00069	0.587
MOD_PKA_2	103	109	PF00069	0.517
MOD_PKA_2	25	31	PF00069	0.594
MOD_PKA_2	45	51	PF00069	0.458
MOD_ProDKin_1	127	133	PF00069	0.747
TRG_ER_diArg_1	138	140	PF00400	0.531
TRG_ER_diArg_1	7	9	PF00400	0.577
TRG_ER_diArg_1	76	79	PF00400	0.445
TRG_NLS_MonoExtN_4	111	117	PF00514	0.559
TRG_Pf-PMV_PEXEL_1	7	12	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4N3	Leptomonas seymouri	73%	100%
A0A0S4J210	Bodo saltans	33%	78%
A4HCL9	Leishmania braziliensis	84%	100%
A4I043	Leishmania infantum	99%	100%
C9ZUX9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	93%
E9AW06	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QBH0	Leishmania major	92%	100%