LeishMANIAdb
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Uncharacterized protein family UPF0066, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein family UPF0066, putative
Gene product:
Uncharacterised protein family UPF0066, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WX66_LEIDO
TriTrypDb:
LdBPK_220460.1 * , LdCL_220010900 , LDHU3_22.0780
Length:
492

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WX66
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WX66

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 465 469 PF00656 0.535
CLV_NRD_NRD_1 108 110 PF00675 0.591
CLV_NRD_NRD_1 116 118 PF00675 0.609
CLV_NRD_NRD_1 317 319 PF00675 0.652
CLV_NRD_NRD_1 378 380 PF00675 0.481
CLV_PCSK_FUR_1 112 116 PF00082 0.416
CLV_PCSK_KEX2_1 114 116 PF00082 0.652
CLV_PCSK_KEX2_1 377 379 PF00082 0.483
CLV_PCSK_KEX2_1 48 50 PF00082 0.614
CLV_PCSK_PC1ET2_1 48 50 PF00082 0.633
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PB52 Leptomonas seymouri 67% 100%
A0A3R7K8Q3 Trypanosoma rangeli 49% 100%
A4HCA4 Leishmania braziliensis 78% 100%
A4HZT6 Leishmania infantum 100% 100%
C9ZRM2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 48% 100%
E9AVP1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4QBT8 Leishmania major 91% 99%
V5DMI0 Trypanosoma cruzi 48% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS