Proteasome_regulatory_ATPase_subunit_1_putative/G eneDB:LmjF.22.0570

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

proteasome regulatory ATPase subunit 1, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WX46_LEIDO

TriTrypDb:

LdBPK_220440.1 , LdCL_220010700 , LDHU3_22.0760

Length:

437

Annotations

LeishMANIAdb annotations

A large and likely artifical grouping of protease domain carrying proteins related to proteasomal proteases. Only a tiny subgroup (the AFG3-related mitochondrail proteins) seem to have a TM segment.. Localization: Cytoplasmic (by homology) / Mitochondrial (by homology)

Annotations by Jardim et al.

Proteasome, proteasome regulatory ATPase subunit 1

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0000502	proteasome complex	3	11
GO:0005737	cytoplasm	2	12
GO:0032991	protein-containing complex	1	12
GO:0110165	cellular anatomical entity	1	12
GO:0140535	intracellular protein-containing complex	2	11
GO:1902494	catalytic complex	2	11
GO:1905368	peptidase complex	3	11
GO:1905369	endopeptidase complex	4	11
GO:0005654	nucleoplasm	2	1
GO:0008540	proteasome regulatory particle, base subcomplex	2	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3S7WX46

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WX46

Function

Biological processes
Term	Name	Level	Count
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009056	catabolic process	2	12
GO:0009057	macromolecule catabolic process	4	12
GO:0019538	protein metabolic process	3	12
GO:0030163	protein catabolic process	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044238	primary metabolic process	2	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901565	organonitrogen compound catabolic process	4	12
GO:1901575	organic substance catabolic process	3	12
GO:0006508	proteolysis	4	1
GO:0006511	ubiquitin-dependent protein catabolic process	7	1
GO:0009987	cellular process	1	1
GO:0010498	proteasomal protein catabolic process	5	1
GO:0019941	modification-dependent protein catabolic process	6	1
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	6	1
GO:0043632	modification-dependent macromolecule catabolic process	5	1
GO:0044237	cellular metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0051603	proteolysis involved in protein catabolic process	5	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0036402	proteasome-activating activity	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	281	285	PF00656	0.269
CLV_C14_Caspase3-7	412	416	PF00656	0.285
CLV_NRD_NRD_1	342	344	PF00675	0.271
CLV_NRD_NRD_1	404	406	PF00675	0.269
CLV_PCSK_FUR_1	402	406	PF00082	0.269
CLV_PCSK_KEX2_1	404	406	PF00082	0.269
CLV_PCSK_SKI1_1	216	220	PF00082	0.269
CLV_PCSK_SKI1_1	228	232	PF00082	0.269
CLV_PCSK_SKI1_1	264	268	PF00082	0.269
CLV_PCSK_SKI1_1	301	305	PF00082	0.269
CLV_PCSK_SKI1_1	406	410	PF00082	0.284
CLV_PCSK_SKI1_1	411	415	PF00082	0.256
CLV_PCSK_SKI1_1	419	423	PF00082	0.354
DEG_APCC_DBOX_1	300	308	PF00400	0.269
DOC_ANK_TNKS_1	253	260	PF00023	0.269
DOC_ANK_TNKS_1	289	296	PF00023	0.329
DOC_MAPK_gen_1	162	172	PF00069	0.559
DOC_MAPK_gen_1	192	201	PF00069	0.360
DOC_MAPK_gen_1	21	29	PF00069	0.642
DOC_MAPK_gen_1	271	280	PF00069	0.269
DOC_MAPK_gen_1	337	347	PF00069	0.269
DOC_MAPK_MEF2A_6	152	159	PF00069	0.398
DOC_MAPK_MEF2A_6	192	201	PF00069	0.360
DOC_MAPK_MEF2A_6	316	323	PF00069	0.269
DOC_MAPK_MEF2A_6	340	349	PF00069	0.269
DOC_PP1_RVXF_1	368	375	PF00149	0.269
DOC_USP7_UBL2_3	17	21	PF12436	0.693
DOC_USP7_UBL2_3	422	426	PF12436	0.421
LIG_14-3-3_CanoR_1	165	170	PF00244	0.565
LIG_14-3-3_CanoR_1	364	372	PF00244	0.519
LIG_14-3-3_CanoR_1	390	399	PF00244	0.269
LIG_14-3-3_CanoR_1	405	414	PF00244	0.269
LIG_BIR_II_1	1	5	PF00653	0.574
LIG_BIR_III_4	284	288	PF00653	0.269
LIG_FHA_1	11	17	PF00498	0.572
LIG_FHA_1	354	360	PF00498	0.341
LIG_FHA_2	126	132	PF00498	0.530
LIG_FHA_2	177	183	PF00498	0.393
LIG_FHA_2	200	206	PF00498	0.390
LIG_FHA_2	300	306	PF00498	0.269
LIG_FHA_2	383	389	PF00498	0.269
LIG_FHA_2	405	411	PF00498	0.269
LIG_LIR_Gen_1	177	186	PF02991	0.399
LIG_LIR_Gen_1	205	215	PF02991	0.404
LIG_LIR_Gen_1	240	251	PF02991	0.269
LIG_LIR_Gen_1	371	382	PF02991	0.329
LIG_LIR_Nem_3	177	183	PF02991	0.393
LIG_LIR_Nem_3	205	210	PF02991	0.407
LIG_LIR_Nem_3	240	246	PF02991	0.269
LIG_LIR_Nem_3	371	377	PF02991	0.329
LIG_LIR_Nem_3	430	436	PF02991	0.399
LIG_MYND_3	349	353	PF01753	0.377
LIG_RPA_C_Fungi	233	245	PF08784	0.269
LIG_SH2_CRK	150	154	PF00017	0.421
LIG_SH2_CRK	207	211	PF00017	0.419
LIG_SH2_CRK	221	225	PF00017	0.237
LIG_SH2_NCK_1	150	154	PF00017	0.499
LIG_SH2_NCK_1	180	184	PF00017	0.379
LIG_SH2_SRC	115	118	PF00017	0.431
LIG_SH2_SRC	180	183	PF00017	0.478
LIG_SH2_STAT5	115	118	PF00017	0.337
LIG_SH2_STAT5	125	128	PF00017	0.368
LIG_SH2_STAT5	207	210	PF00017	0.421
LIG_SH2_STAT5	255	258	PF00017	0.269
LIG_SH3_3	155	161	PF00018	0.373
LIG_SH3_3	194	200	PF00018	0.361
LIG_SUMO_SIM_anti_2	32	38	PF11976	0.428
LIG_SUMO_SIM_par_1	115	121	PF11976	0.405
LIG_SUMO_SIM_par_1	125	131	PF11976	0.435
LIG_TYR_ITIM	178	183	PF00017	0.383
LIG_UBA3_1	26	31	PF00899	0.548
LIG_UBA3_1	266	274	PF00899	0.269
LIG_UBA3_1	398	406	PF00899	0.269
LIG_WW_3	159	163	PF00397	0.409
MOD_CK1_1	289	295	PF00069	0.411
MOD_CK1_1	391	397	PF00069	0.269
MOD_CK2_1	115	121	PF00069	0.561
MOD_CK2_1	125	131	PF00069	0.470
MOD_CK2_1	199	205	PF00069	0.387
MOD_CK2_1	299	305	PF00069	0.269
MOD_CK2_1	404	410	PF00069	0.269
MOD_CK2_1	45	51	PF00069	0.494
MOD_CK2_1	55	61	PF00069	0.394
MOD_GlcNHglycan	291	294	PF01048	0.367
MOD_GlcNHglycan	41	44	PF01048	0.445
MOD_GlcNHglycan	427	430	PF01048	0.396
MOD_GSK3_1	360	367	PF00069	0.426
MOD_LATS_1	362	368	PF00433	0.371
MOD_N-GLC_1	236	241	PF02516	0.269
MOD_N-GLC_1	382	387	PF02516	0.269
MOD_NEK2_1	148	153	PF00069	0.421
MOD_NEK2_1	269	274	PF00069	0.269
MOD_NEK2_1	39	44	PF00069	0.438
MOD_NEK2_1	413	418	PF00069	0.428
MOD_NEK2_1	427	432	PF00069	0.331
MOD_NEK2_1	55	60	PF00069	0.390
MOD_NEK2_2	115	120	PF00069	0.416
MOD_NEK2_2	45	50	PF00069	0.460
MOD_PIKK_1	205	211	PF00454	0.424
MOD_PKA_1	404	410	PF00069	0.269
MOD_PKA_2	289	295	PF00069	0.411
MOD_PKA_2	404	410	PF00069	0.269
MOD_PKB_1	402	410	PF00069	0.269
MOD_Plk_1	138	144	PF00069	0.395
MOD_Plk_1	163	169	PF00069	0.488
MOD_Plk_1	176	182	PF00069	0.332
MOD_Plk_1	239	245	PF00069	0.269
MOD_Plk_4	165	171	PF00069	0.418
MOD_Plk_4	226	232	PF00069	0.269
MOD_Plk_4	239	245	PF00069	0.269
MOD_SUMO_rev_2	168	176	PF00179	0.434
MOD_SUMO_rev_2	18	26	PF00179	0.569
MOD_SUMO_rev_2	83	91	PF00179	0.525
TRG_DiLeu_BaEn_2	50	56	PF01217	0.431
TRG_ENDOCYTIC_2	150	153	PF00928	0.430
TRG_ENDOCYTIC_2	180	183	PF00928	0.384
TRG_ENDOCYTIC_2	207	210	PF00928	0.421
TRG_ER_diArg_1	401	404	PF00400	0.269
TRG_NES_CRM1_1	191	205	PF08389	0.374
TRG_Pf-PMV_PEXEL_1	254	258	PF00026	0.269
TRG_Pf-PMV_PEXEL_1	261	265	PF00026	0.269
TRG_Pf-PMV_PEXEL_1	364	369	PF00026	0.519
TRG_Pf-PMV_PEXEL_1	50	54	PF00026	0.417

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4E9	Leptomonas seymouri	50%	100%
A0A0N0P5B8	Leptomonas seymouri	47%	98%
A0A0N0P7K1	Leptomonas seymouri	53%	100%
A0A0N1IGY9	Leptomonas seymouri	45%	100%
A0A0N1IM81	Leptomonas seymouri	42%	100%
A0A0N1PAS8	Leptomonas seymouri	97%	100%
A0A0S4IJE6	Bodo saltans	81%	100%
A0A0S4IY28	Bodo saltans	50%	100%
A0A0S4JCD0	Bodo saltans	46%	100%
A0A0S4JDU3	Bodo saltans	51%	100%
A0A0S4JSD8	Bodo saltans	47%	100%
A0A1X0NMZ3	Trypanosomatidae	44%	100%
A0A1X0NNS1	Trypanosomatidae	46%	100%
A0A1X0NUX3	Trypanosomatidae	85%	100%
A0A1X0P1T5	Trypanosomatidae	50%	100%
A0A1X0P8T7	Trypanosomatidae	49%	100%
A0A3Q8IJS0	Leishmania donovani	51%	100%
A0A3R7N4Y5	Trypanosoma rangeli	50%	100%
A0A3S5H547	Leishmania donovani	50%	100%
A0A3S7WRY0	Leishmania donovani	45%	100%
A0A3S7WSK7	Leishmania donovani	42%	100%
A0A3S7WX14	Leishmania donovani	49%	98%
A0A422NDS9	Trypanosoma rangeli	85%	100%
A0A422NLD8	Trypanosoma rangeli	45%	100%
A0A422NMN6	Trypanosoma rangeli	49%	100%
A0A422NUD9	Trypanosoma rangeli	46%	100%
A3CV35	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	44%	100%
A4G0S4	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	50%	100%
A4H3L6	Leishmania braziliensis	50%	100%
A4H6T6	Leishmania braziliensis	45%	100%
A4H795	Leishmania braziliensis	42%	100%
A4HCA3	Leishmania braziliensis	98%	100%
A4HCA7	Leishmania braziliensis	49%	98%
A4HPV3	Leishmania braziliensis	50%	100%
A4HVN7	Leishmania infantum	42%	100%
A4HZT4	Leishmania infantum	100%	100%
A4HZT9	Leishmania infantum	49%	98%
A4IE38	Leishmania infantum	51%	100%
A6UQT3	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	50%	100%
A6VHR1	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	47%	100%
A7I8B8	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	50%	100%
A9A916	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	51%	100%
B6YXR2	Thermococcus onnurineus (strain NA1)	45%	100%
B8DTX4	Bifidobacterium animalis subsp. lactis (strain AD011)	35%	84%
B8GGN4	Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)	46%	100%
C3MRF1	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	45%	100%
C3MY47	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	45%	100%
C3MZI6	Sulfolobus islandicus (strain M.16.27)	45%	100%
C3N7K8	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	45%	100%
C3NFW6	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	45%	100%
C4KIR6	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	45%	100%
C5A6P8	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	47%	100%
C6A7B2	Bifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219)	35%	84%
C6AHX0	Bifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314)	35%	84%
C7M0M0	Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)	39%	66%
C7MCZ0	Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 / NCIMB 9860 / 6-10)	31%	82%
C7PVU9	Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)	35%	74%
C9ZQC1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
C9ZRM0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	84%	100%
D0A259	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
D0A4A2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
D0A6K9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
D3R4I7	Bifidobacterium animalis subsp. lactis (strain BB-12)	35%	83%
D4GUJ7	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	45%	100%
E9ACJ9	Leishmania major	49%	100%
E9AG43	Leishmania infantum	50%	100%
E9AGB0	Leishmania infantum	45%	100%
E9AJT7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
E9ANU8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9APD3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9ATM0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
E9AVN9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9AVP4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	98%
O04019	Arabidopsis thaliana	48%	100%
O14126	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	100%
O16368	Caenorhabditis elegans	47%	99%
O17071	Caenorhabditis elegans	48%	100%
O18413	Drosophila melanogaster	47%	100%
O23894	Brassica campestris	48%	100%
O26824	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	47%	100%
O28303	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	51%	100%
O42586	Xenopus laevis	46%	100%
O42587	Xenopus laevis	46%	100%
O42931	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	63%	100%
O57940	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	47%	100%
O64982	Prunus persica	69%	100%
O74445	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	100%
O74894	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	45%	100%
O76371	Caenorhabditis elegans	45%	100%
O88685	Mus musculus	46%	99%
P0DKJ9	Oryza sativa subsp. japonica	69%	100%
P0DKK0	Oryza sativa subsp. japonica	69%	100%
P17980	Homo sapiens	46%	100%
P33298	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	46%	100%
P33299	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	61%	94%
P34124	Dictyostelium discoideum	46%	100%
P35998	Homo sapiens	64%	100%
P36612	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	44%	98%
P40327	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	100%
P41836	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	50%	100%
P46465	Oryza sativa subsp. japonica	48%	100%
P46466	Oryza sativa subsp. japonica	46%	98%
P46470	Xenopus laevis	50%	95%
P46471	Mus musculus	63%	100%
P46472	Xenopus laevis	65%	100%
P46508	Schistosoma mansoni	32%	66%
P48601	Drosophila melanogaster	45%	100%
P53549	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	46%	100%
P54776	Solanum lycopersicum	48%	100%
P54778	Solanum tuberosum	47%	100%
P54814	Manduca sexta	47%	100%
P62191	Homo sapiens	45%	99%
P62192	Mus musculus	45%	99%
P62193	Rattus norvegicus	45%	99%
P62194	Bos taurus	51%	100%
P62195	Homo sapiens	51%	100%
P62196	Mus musculus	51%	100%
P62197	Sus scrofa	51%	100%
P62198	Rattus norvegicus	51%	100%
P62333	Homo sapiens	49%	100%
P62334	Mus musculus	49%	100%
P62335	Ictidomys tridecemlineatus	49%	100%
P78578	Aspergillus niger	49%	100%
P85200	Helianthus annuus	46%	100%
Q01939	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	44%	100%
Q0W257	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	46%	100%
Q18787	Caenorhabditis elegans	62%	100%
Q25544	Naegleria fowleri	47%	100%
Q2FQ56	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	48%	100%
Q2KIW6	Bos taurus	49%	100%
Q41365	Spinacia oleracea	70%	100%
Q4JVP5	Corynebacterium jeikeium (strain K411)	38%	85%
Q4Q0X8	Leishmania major	51%	100%
Q4QBT5	Leishmania major	49%	98%
Q4QBU0	Leishmania major	100%	100%
Q4QG45	Leishmania major	42%	100%
Q4QGS2	Leishmania major	45%	100%
Q4R4R0	Macaca fascicularis	64%	100%
Q55BV5	Dictyostelium discoideum	43%	100%
Q58576	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	49%	100%
Q5E9F9	Bos taurus	64%	100%
Q5JHS5	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	47%	100%
Q5R8D7	Pongo abelii	64%	100%
Q63347	Rattus norvegicus	63%	100%
Q63569	Rattus norvegicus	46%	100%
Q6LWR0	Methanococcus maripaludis (strain S2 / LL)	46%	100%
Q86JA1	Dictyostelium discoideum	64%	100%
Q8SQK0	Encephalitozoon cuniculi (strain GB-M1)	52%	100%
Q8SRH0	Encephalitozoon cuniculi (strain GB-M1)	47%	100%
Q8TX03	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	48%	100%
Q8U4H3	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	44%	100%
Q90732	Gallus gallus	47%	99%
Q94BQ2	Arabidopsis thaliana	46%	100%
Q975U2	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	40%	100%
Q980M1	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	44%	100%
Q9C5U3	Arabidopsis thaliana	47%	100%
Q9HNP9	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	43%	100%
Q9HRW6	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	41%	100%
Q9M895	Arabidopsis thaliana	39%	70%
Q9MAK9	Arabidopsis thaliana	47%	100%
Q9SEI2	Arabidopsis thaliana	48%	100%
Q9SEI3	Arabidopsis thaliana	44%	100%
Q9SEI4	Arabidopsis thaliana	49%	100%
Q9SL67	Arabidopsis thaliana	46%	99%
Q9SSB4	Arabidopsis thaliana	65%	94%
Q9SSB5	Arabidopsis thaliana	68%	100%
Q9SZD4	Arabidopsis thaliana	46%	99%
Q9V287	Pyrococcus abyssi (strain GE5 / Orsay)	43%	100%
Q9XTT9	Caenorhabditis elegans	47%	100%
V5AV12	Trypanosoma cruzi	45%	100%
V5B5X1	Trypanosoma cruzi	85%	100%
V5BKL6	Trypanosoma cruzi	49%	100%
V5BSS5	Trypanosoma cruzi	48%	100%