Glucoamylase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glucoamylase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7WX15_LEIDO

TriTrypDb:

LdBPK_220530.1 , LdCL_220011600 , LDHU3_22.0860

Length:

1108

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WX15

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WX15

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	175	179	PF00656	0.631
CLV_C14_Caspase3-7	631	635	PF00656	0.564
CLV_C14_Caspase3-7	679	683	PF00656	0.695
CLV_C14_Caspase3-7	923	927	PF00656	0.658
CLV_C14_Caspase3-7	931	935	PF00656	0.565
CLV_NRD_NRD_1	101	103	PF00675	0.702
CLV_NRD_NRD_1	358	360	PF00675	0.675
CLV_NRD_NRD_1	424	426	PF00675	0.667
CLV_NRD_NRD_1	464	466	PF00675	0.570
CLV_NRD_NRD_1	779	781	PF00675	0.564
CLV_NRD_NRD_1	790	792	PF00675	0.533
CLV_NRD_NRD_1	915	917	PF00675	0.568
CLV_NRD_NRD_1	984	986	PF00675	0.650
CLV_PCSK_KEX2_1	101	103	PF00082	0.702
CLV_PCSK_KEX2_1	358	360	PF00082	0.678
CLV_PCSK_KEX2_1	423	425	PF00082	0.668
CLV_PCSK_KEX2_1	464	466	PF00082	0.570
CLV_PCSK_KEX2_1	646	648	PF00082	0.675
CLV_PCSK_KEX2_1	779	781	PF00082	0.564
CLV_PCSK_KEX2_1	790	792	PF00082	0.533
CLV_PCSK_KEX2_1	915	917	PF00082	0.568
CLV_PCSK_KEX2_1	984	986	PF00082	0.604
CLV_PCSK_PC1ET2_1	646	648	PF00082	0.675
CLV_PCSK_PC7_1	980	986	PF00082	0.592
CLV_PCSK_SKI1_1	1020	1024	PF00082	0.698
CLV_PCSK_SKI1_1	1051	1055	PF00082	0.660
CLV_PCSK_SKI1_1	538	542	PF00082	0.601
CLV_PCSK_SKI1_1	569	573	PF00082	0.590
CLV_PCSK_SKI1_1	647	651	PF00082	0.580
CLV_PCSK_SKI1_1	668	672	PF00082	0.761
CLV_PCSK_SKI1_1	735	739	PF00082	0.490
DEG_SCF_FBW7_1	171	176	PF00400	0.592
DEG_SCF_FBW7_1	591	598	PF00400	0.609
DEG_SCF_TRCP1_1	232	237	PF00400	0.670
DEG_SPOP_SBC_1	398	402	PF00917	0.670
DEG_SPOP_SBC_1	509	513	PF00917	0.652
DOC_CKS1_1	106	111	PF01111	0.650
DOC_CKS1_1	630	635	PF01111	0.624
DOC_CKS1_1	874	879	PF01111	0.698
DOC_CYCLIN_RxL_1	535	544	PF00134	0.585
DOC_CYCLIN_RxL_1	744	752	PF00134	0.325
DOC_MAPK_gen_1	358	366	PF00069	0.647
DOC_PP2B_LxvP_1	808	811	PF13499	0.645
DOC_PP4_FxxP_1	1091	1094	PF00568	0.703
DOC_PP4_FxxP_1	117	120	PF00568	0.659
DOC_PP4_FxxP_1	416	419	PF00568	0.537
DOC_USP7_MATH_1	1049	1053	PF00917	0.578
DOC_USP7_MATH_1	143	147	PF00917	0.611
DOC_USP7_MATH_1	182	186	PF00917	0.697
DOC_USP7_MATH_1	19	23	PF00917	0.664
DOC_USP7_MATH_1	210	214	PF00917	0.635
DOC_USP7_MATH_1	25	29	PF00917	0.659
DOC_USP7_MATH_1	254	258	PF00917	0.673
DOC_USP7_MATH_1	30	34	PF00917	0.631
DOC_USP7_MATH_1	373	377	PF00917	0.684
DOC_USP7_MATH_1	38	42	PF00917	0.565
DOC_USP7_MATH_1	399	403	PF00917	0.682
DOC_USP7_MATH_1	419	423	PF00917	0.477
DOC_USP7_MATH_1	509	513	PF00917	0.659
DOC_USP7_MATH_1	560	564	PF00917	0.526
DOC_USP7_MATH_1	826	830	PF00917	0.669
DOC_USP7_MATH_1	959	963	PF00917	0.631
DOC_USP7_MATH_1	992	996	PF00917	0.668
DOC_USP7_UBL2_3	1046	1050	PF12436	0.627
DOC_WW_Pin1_4	105	110	PF00397	0.628
DOC_WW_Pin1_4	1101	1106	PF00397	0.694
DOC_WW_Pin1_4	139	144	PF00397	0.622
DOC_WW_Pin1_4	169	174	PF00397	0.621
DOC_WW_Pin1_4	202	207	PF00397	0.688
DOC_WW_Pin1_4	249	254	PF00397	0.680
DOC_WW_Pin1_4	264	269	PF00397	0.523
DOC_WW_Pin1_4	279	284	PF00397	0.504
DOC_WW_Pin1_4	327	332	PF00397	0.642
DOC_WW_Pin1_4	337	342	PF00397	0.599
DOC_WW_Pin1_4	379	384	PF00397	0.672
DOC_WW_Pin1_4	393	398	PF00397	0.535
DOC_WW_Pin1_4	411	416	PF00397	0.497
DOC_WW_Pin1_4	432	437	PF00397	0.636
DOC_WW_Pin1_4	469	474	PF00397	0.662
DOC_WW_Pin1_4	475	480	PF00397	0.640
DOC_WW_Pin1_4	57	62	PF00397	0.649
DOC_WW_Pin1_4	591	596	PF00397	0.608
DOC_WW_Pin1_4	629	634	PF00397	0.640
DOC_WW_Pin1_4	769	774	PF00397	0.638
DOC_WW_Pin1_4	790	795	PF00397	0.653
DOC_WW_Pin1_4	873	878	PF00397	0.700
DOC_WW_Pin1_4	890	895	PF00397	0.544
LIG_14-3-3_CanoR_1	1006	1011	PF00244	0.602
LIG_14-3-3_CanoR_1	15	24	PF00244	0.643
LIG_14-3-3_CanoR_1	165	173	PF00244	0.623
LIG_14-3-3_CanoR_1	327	331	PF00244	0.557
LIG_14-3-3_CanoR_1	361	367	PF00244	0.654
LIG_14-3-3_CanoR_1	504	508	PF00244	0.575
LIG_14-3-3_CanoR_1	718	726	PF00244	0.491
LIG_14-3-3_CanoR_1	735	745	PF00244	0.370
LIG_14-3-3_CanoR_1	77	82	PF00244	0.672
LIG_14-3-3_CanoR_1	996	1003	PF00244	0.597
LIG_APCC_ABBAyCdc20_2	710	716	PF00400	0.488
LIG_BIR_II_1	1	5	PF00653	0.602
LIG_BIR_III_2	168	172	PF00653	0.564
LIG_BIR_III_3	1	5	PF00653	0.602
LIG_BRCT_BRCA1_1	158	162	PF00533	0.642
LIG_BRCT_BRCA1_1	266	270	PF00533	0.576
LIG_BRCT_BRCA1_1	306	310	PF00533	0.611
LIG_BRCT_BRCA1_1	567	571	PF00533	0.574
LIG_Clathr_ClatBox_1	1082	1086	PF01394	0.617
LIG_EVH1_1	808	812	PF00568	0.645
LIG_EVH1_2	63	67	PF00568	0.644
LIG_EVH1_2	971	975	PF00568	0.673
LIG_FHA_1	1005	1011	PF00498	0.643
LIG_FHA_1	260	266	PF00498	0.610
LIG_FHA_1	29	35	PF00498	0.692
LIG_FHA_1	332	338	PF00498	0.705
LIG_FHA_1	736	742	PF00498	0.571
LIG_FHA_1	816	822	PF00498	0.543
LIG_FHA_1	951	957	PF00498	0.620
LIG_FHA_2	206	212	PF00498	0.561
LIG_FHA_2	379	385	PF00498	0.670
LIG_FHA_2	874	880	PF00498	0.650
LIG_FHA_2	909	915	PF00498	0.674
LIG_FHA_2	921	927	PF00498	0.588
LIG_IRF3_LxIS_1	903	908	PF10401	0.629
LIG_LIR_Apic_2	1088	1094	PF02991	0.701
LIG_LIR_Apic_2	287	293	PF02991	0.574
LIG_LIR_Apic_2	391	397	PF02991	0.639
LIG_LIR_Apic_2	414	419	PF02991	0.537
LIG_LIR_Gen_1	100	110	PF02991	0.565
LIG_LIR_Gen_1	156	163	PF02991	0.623
LIG_LIR_Gen_1	282	293	PF02991	0.535
LIG_LIR_Gen_1	437	443	PF02991	0.622
LIG_LIR_Gen_1	522	531	PF02991	0.571
LIG_LIR_Gen_1	739	749	PF02991	0.472
LIG_LIR_Nem_3	100	106	PF02991	0.567
LIG_LIR_Nem_3	156	160	PF02991	0.622
LIG_LIR_Nem_3	282	288	PF02991	0.534
LIG_LIR_Nem_3	437	442	PF02991	0.628
LIG_LIR_Nem_3	522	527	PF02991	0.570
LIG_LIR_Nem_3	739	745	PF02991	0.481
LIG_Pex14_2	571	575	PF04695	0.579
LIG_REV1ctd_RIR_1	160	169	PF16727	0.670
LIG_REV1ctd_RIR_1	570	580	PF16727	0.586
LIG_SH2_CRK	103	107	PF00017	0.571
LIG_SH2_CRK	157	161	PF00017	0.514
LIG_SH2_CRK	394	398	PF00017	0.625
LIG_SH2_CRK	742	746	PF00017	0.473
LIG_SH2_GRB2like	405	408	PF00017	0.555
LIG_SH2_GRB2like	742	745	PF00017	0.476
LIG_SH2_NCK_1	394	398	PF00017	0.625
LIG_SH2_NCK_1	439	443	PF00017	0.670
LIG_SH2_NCK_1	742	746	PF00017	0.473
LIG_SH2_PTP2	290	293	PF00017	0.516
LIG_SH2_SRC	405	408	PF00017	0.555
LIG_SH2_SRC	439	442	PF00017	0.629
LIG_SH2_SRC	742	745	PF00017	0.476
LIG_SH2_STAT5	1013	1016	PF00017	0.694
LIG_SH2_STAT5	103	106	PF00017	0.572
LIG_SH2_STAT5	290	293	PF00017	0.516
LIG_SH2_STAT5	952	955	PF00017	0.685
LIG_SH3_3	103	109	PF00018	0.632
LIG_SH3_3	1068	1074	PF00018	0.637
LIG_SH3_3	174	180	PF00018	0.635
LIG_SH3_3	2	8	PF00018	0.650
LIG_SH3_3	305	311	PF00018	0.589
LIG_SH3_3	58	64	PF00018	0.684
LIG_SH3_3	627	633	PF00018	0.688
LIG_SH3_3	770	776	PF00018	0.598
LIG_SH3_3	806	812	PF00018	0.649
LIG_SH3_3	818	824	PF00018	0.553
LIG_SH3_3	86	92	PF00018	0.558
LIG_SH3_3	871	877	PF00018	0.699
LIG_SH3_4	1046	1053	PF00018	0.554
LIG_SUMO_SIM_par_1	1081	1088	PF11976	0.618
LIG_SUMO_SIM_par_1	551	557	PF11976	0.552
LIG_TRAF2_1	1041	1044	PF00917	0.683
LIG_TRAF2_1	213	216	PF00917	0.651
LIG_WW_2	63	66	PF00397	0.636
MOD_CDK_SPxK_1	890	896	PF00069	0.719
MOD_CK1_1	10	16	PF00069	0.652
MOD_CK1_1	1052	1058	PF00069	0.610
MOD_CK1_1	18	24	PF00069	0.620
MOD_CK1_1	185	191	PF00069	0.630
MOD_CK1_1	256	262	PF00069	0.667
MOD_CK1_1	26	32	PF00069	0.590
MOD_CK1_1	326	332	PF00069	0.616
MOD_CK1_1	33	39	PF00069	0.623
MOD_CK1_1	382	388	PF00069	0.667
MOD_CK1_1	434	440	PF00069	0.599
MOD_CK1_1	522	528	PF00069	0.573
MOD_CK1_1	623	629	PF00069	0.607
MOD_CK1_1	695	701	PF00069	0.634
MOD_CK1_1	79	85	PF00069	0.667
MOD_CK1_1	908	914	PF00069	0.661
MOD_CK1_1	995	1001	PF00069	0.688
MOD_CK2_1	210	216	PF00069	0.658
MOD_CK2_1	378	384	PF00069	0.673
MOD_CK2_1	482	488	PF00069	0.633
MOD_CK2_1	541	547	PF00069	0.639
MOD_CK2_1	908	914	PF00069	0.666
MOD_CK2_1	995	1001	PF00069	0.698
MOD_Cter_Amidation	982	985	PF01082	0.596
MOD_DYRK1A_RPxSP_1	105	109	PF00069	0.649
MOD_DYRK1A_RPxSP_1	327	331	PF00069	0.557
MOD_GlcNHglycan	1034	1037	PF01048	0.728
MOD_GlcNHglycan	1090	1094	PF01048	0.654
MOD_GlcNHglycan	137	140	PF01048	0.748
MOD_GlcNHglycan	17	20	PF01048	0.668
MOD_GlcNHglycan	187	190	PF01048	0.629
MOD_GlcNHglycan	21	24	PF01048	0.637
MOD_GlcNHglycan	228	231	PF01048	0.650
MOD_GlcNHglycan	232	235	PF01048	0.644
MOD_GlcNHglycan	246	250	PF01048	0.538
MOD_GlcNHglycan	28	31	PF01048	0.627
MOD_GlcNHglycan	375	378	PF01048	0.660
MOD_GlcNHglycan	390	393	PF01048	0.577
MOD_GlcNHglycan	436	439	PF01048	0.643
MOD_GlcNHglycan	44	47	PF01048	0.552
MOD_GlcNHglycan	458	461	PF01048	0.631
MOD_GlcNHglycan	505	508	PF01048	0.702
MOD_GlcNHglycan	517	520	PF01048	0.555
MOD_GlcNHglycan	523	527	PF01048	0.429
MOD_GlcNHglycan	531	534	PF01048	0.452
MOD_GlcNHglycan	640	644	PF01048	0.595
MOD_GlcNHglycan	720	723	PF01048	0.478
MOD_GlcNHglycan	764	767	PF01048	0.462
MOD_GlcNHglycan	907	910	PF01048	0.629
MOD_GlcNHglycan	961	964	PF01048	0.626
MOD_GlcNHglycan	990	993	PF01048	0.680
MOD_GSK3_1	1002	1009	PF00069	0.525
MOD_GSK3_1	101	108	PF00069	0.632
MOD_GSK3_1	1097	1104	PF00069	0.706
MOD_GSK3_1	135	142	PF00069	0.715
MOD_GSK3_1	15	22	PF00069	0.680
MOD_GSK3_1	169	176	PF00069	0.596
MOD_GSK3_1	210	217	PF00069	0.680
MOD_GSK3_1	226	233	PF00069	0.526
MOD_GSK3_1	245	252	PF00069	0.531
MOD_GSK3_1	25	32	PF00069	0.618
MOD_GSK3_1	264	271	PF00069	0.502
MOD_GSK3_1	279	286	PF00069	0.517
MOD_GSK3_1	323	330	PF00069	0.689
MOD_GSK3_1	33	40	PF00069	0.562
MOD_GSK3_1	342	349	PF00069	0.487
MOD_GSK3_1	362	369	PF00069	0.494
MOD_GSK3_1	378	385	PF00069	0.554
MOD_GSK3_1	393	400	PF00069	0.522
MOD_GSK3_1	42	49	PF00069	0.546
MOD_GSK3_1	428	435	PF00069	0.600
MOD_GSK3_1	456	463	PF00069	0.636
MOD_GSK3_1	469	476	PF00069	0.564
MOD_GSK3_1	490	497	PF00069	0.602
MOD_GSK3_1	515	522	PF00069	0.652
MOD_GSK3_1	591	598	PF00069	0.633
MOD_GSK3_1	620	627	PF00069	0.658
MOD_GSK3_1	635	642	PF00069	0.637
MOD_GSK3_1	66	73	PF00069	0.631
MOD_GSK3_1	76	83	PF00069	0.605
MOD_GSK3_1	91	98	PF00069	0.596
MOD_GSK3_1	988	995	PF00069	0.674
MOD_N-GLC_1	314	319	PF02516	0.644
MOD_N-GLC_1	369	374	PF02516	0.632
MOD_N-GLC_1	473	478	PF02516	0.628
MOD_N-GLC_1	704	709	PF02516	0.599
MOD_N-GLC_1	735	740	PF02516	0.524
MOD_N-GLC_1	826	831	PF02516	0.616
MOD_N-GLC_2	748	750	PF02516	0.434
MOD_N-GLC_2	796	798	PF02516	0.620
MOD_N-GLC_2	940	942	PF02516	0.607
MOD_NEK2_1	144	149	PF00069	0.694
MOD_NEK2_1	153	158	PF00069	0.630
MOD_NEK2_1	325	330	PF00069	0.692
MOD_NEK2_1	344	349	PF00069	0.485
MOD_NEK2_1	352	357	PF00069	0.614
MOD_NEK2_1	468	473	PF00069	0.578
MOD_NEK2_1	482	487	PF00069	0.598
MOD_NEK2_1	541	546	PF00069	0.594
MOD_NEK2_1	565	570	PF00069	0.602
MOD_NEK2_1	749	754	PF00069	0.385
MOD_NEK2_1	759	764	PF00069	0.423
MOD_NEK2_1	905	910	PF00069	0.628
MOD_NEK2_1	950	955	PF00069	0.632
MOD_NEK2_2	1049	1054	PF00069	0.608
MOD_OFUCOSY	734	740	PF10250	0.516
MOD_PIKK_1	10	16	PF00454	0.643
MOD_PIKK_1	210	216	PF00454	0.660
MOD_PIKK_1	314	320	PF00454	0.597
MOD_PIKK_1	344	350	PF00454	0.682
MOD_PIKK_1	399	405	PF00454	0.636
MOD_PK_1	1006	1012	PF00069	0.672
MOD_PKA_1	101	107	PF00069	0.702
MOD_PKA_2	10	16	PF00069	0.643
MOD_PKA_2	101	107	PF00069	0.668
MOD_PKA_2	164	170	PF00069	0.613
MOD_PKA_2	223	229	PF00069	0.616
MOD_PKA_2	326	332	PF00069	0.562
MOD_PKA_2	357	363	PF00069	0.642
MOD_PKA_2	503	509	PF00069	0.660
MOD_PKA_2	754	760	PF00069	0.555
MOD_PKA_2	76	82	PF00069	0.652
MOD_PKA_2	995	1001	PF00069	0.684
MOD_Plk_1	193	199	PF00069	0.622
MOD_Plk_1	473	479	PF00069	0.626
MOD_Plk_1	522	528	PF00069	0.672
MOD_Plk_1	560	566	PF00069	0.489
MOD_Plk_1	685	691	PF00069	0.713
MOD_Plk_1	704	710	PF00069	0.443
MOD_Plk_1	878	884	PF00069	0.698
MOD_Plk_1	925	931	PF00069	0.685
MOD_Plk_4	194	200	PF00069	0.644
MOD_Plk_4	304	310	PF00069	0.614
MOD_Plk_4	46	52	PF00069	0.627
MOD_Plk_4	749	755	PF00069	0.397
MOD_Plk_4	883	889	PF00069	0.716
MOD_Plk_4	925	931	PF00069	0.610
MOD_ProDKin_1	105	111	PF00069	0.630
MOD_ProDKin_1	1101	1107	PF00069	0.698
MOD_ProDKin_1	139	145	PF00069	0.621
MOD_ProDKin_1	169	175	PF00069	0.622
MOD_ProDKin_1	202	208	PF00069	0.688
MOD_ProDKin_1	249	255	PF00069	0.682
MOD_ProDKin_1	264	270	PF00069	0.526
MOD_ProDKin_1	279	285	PF00069	0.506
MOD_ProDKin_1	327	333	PF00069	0.643
MOD_ProDKin_1	337	343	PF00069	0.595
MOD_ProDKin_1	379	385	PF00069	0.670
MOD_ProDKin_1	393	399	PF00069	0.531
MOD_ProDKin_1	411	417	PF00069	0.494
MOD_ProDKin_1	432	438	PF00069	0.636
MOD_ProDKin_1	469	475	PF00069	0.659
MOD_ProDKin_1	57	63	PF00069	0.645
MOD_ProDKin_1	591	597	PF00069	0.608
MOD_ProDKin_1	629	635	PF00069	0.641
MOD_ProDKin_1	769	775	PF00069	0.632
MOD_ProDKin_1	790	796	PF00069	0.656
MOD_ProDKin_1	873	879	PF00069	0.698
MOD_ProDKin_1	890	896	PF00069	0.545
MOD_SUMO_for_1	690	693	PF00179	0.639
MOD_SUMO_rev_2	1044	1052	PF00179	0.634
MOD_SUMO_rev_2	1058	1066	PF00179	0.492
TRG_DiLeu_BaEn_1	194	199	PF01217	0.542
TRG_DiLeu_BaEn_2	560	566	PF01217	0.565
TRG_DiLeu_BaEn_4	194	200	PF01217	0.600
TRG_DiLeu_BaLyEn_6	464	469	PF01217	0.562
TRG_ENDOCYTIC_2	103	106	PF00928	0.572
TRG_ENDOCYTIC_2	157	160	PF00928	0.516
TRG_ENDOCYTIC_2	439	442	PF00928	0.629
TRG_ENDOCYTIC_2	742	745	PF00928	0.476
TRG_ER_diArg_1	101	103	PF00400	0.569
TRG_ER_diArg_1	1099	1102	PF00400	0.705
TRG_ER_diArg_1	358	361	PF00400	0.684
TRG_ER_diArg_1	423	425	PF00400	0.644
TRG_ER_diArg_1	778	780	PF00400	0.509
TRG_Pf-PMV_PEXEL_1	1012	1017	PF00026	0.695
TRG_Pf-PMV_PEXEL_1	300	305	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	54	58	PF00026	0.646
TRG_Pf-PMV_PEXEL_1	779	783	PF00026	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HCB0	Leishmania braziliensis	59%	100%
A4HZU3	Leishmania infantum	99%	100%
E9AVP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	99%
Q4QBT1	Leishmania major	87%	100%