Microtubule-binding protein MIP-T3, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Microtubule-binding protein MIP-T3, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WWV8_LEIDO

TriTrypDb:

LdBPK_211880.1 , LdCL_210024500 , LDHU3_21.2250

Length:

485

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Show entries

Cellular components
Term	Name	Level	Count
GO:0005813	centrosome	3	1
GO:0005815	microtubule organizing center	2	1
GO:0005930	axoneme	2	1
GO:0030992	intraciliary transport particle B	2	1
GO:0032991	protein-containing complex	1	1
GO:0036064	ciliary basal body	3	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Expansion

Sequence features

A0A3S7WWV8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWV8

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006996	organelle organization	4	1
GO:0007017	microtubule-based process	2	1
GO:0007018	microtubule-based movement	3	1
GO:0009987	cellular process	1	1
GO:0010970	transport along microtubule	4	1
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0030030	cell projection organization	4	1
GO:0030031	cell projection assembly	5	1

Previous1 2 3 4Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	6
GO:0005515	protein binding	2	6
GO:0008017	microtubule binding	5	6
GO:0008092	cytoskeletal protein binding	3	6
GO:0015631	tubulin binding	4	6

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	401	405	PF00656	0.636
CLV_C14_Caspase3-7	55	59	PF00656	0.636
CLV_NRD_NRD_1	125	127	PF00675	0.544
CLV_NRD_NRD_1	167	169	PF00675	0.629
CLV_NRD_NRD_1	174	176	PF00675	0.568
CLV_NRD_NRD_1	223	225	PF00675	0.786
CLV_NRD_NRD_1	239	241	PF00675	0.850
CLV_NRD_NRD_1	333	335	PF00675	0.345
CLV_NRD_NRD_1	428	430	PF00675	0.435
CLV_PCSK_FUR_1	164	168	PF00082	0.741

Previous1 2 3 4 5…13Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A4HC10	Leishmania braziliensis	79%	99%
A4HZM1	Leishmania infantum	100%	100%
E9AVE7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QC32	Leishmania major	95%	100%

Previous1Next