Nodulin-like domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WWU1_LEIDO

TriTrypDb:

LdBPK_211930.1 , LdCL_210025000 , LDHU3_21.2310

Length:

664

Annotations

LeishMANIAdb annotations

Nutrient transporter belonging to the Major Facilitator Superfamily (MFS). Probable nutrient transporter. Heavily expanded in all parazitic species.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 36

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 120
NetGPI	no	yes: 0, no: 120

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	113
GO:0110165	cellular anatomical entity	1	113
GO:0005737	cytoplasm	2	3

Expansion

Sequence features

A0A3S7WWU1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWU1

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	53
GO:0022857	transmembrane transporter activity	2	53

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	197	201	PF00656	0.381
CLV_NRD_NRD_1	232	234	PF00675	0.307
CLV_NRD_NRD_1	252	254	PF00675	0.303
CLV_NRD_NRD_1	28	30	PF00675	0.347
CLV_NRD_NRD_1	41	43	PF00675	0.240
CLV_NRD_NRD_1	482	484	PF00675	0.364
CLV_NRD_NRD_1	575	577	PF00675	0.561
CLV_PCSK_KEX2_1	232	234	PF00082	0.309
CLV_PCSK_KEX2_1	41	43	PF00082	0.292
CLV_PCSK_KEX2_1	444	446	PF00082	0.598
CLV_PCSK_KEX2_1	575	577	PF00082	0.537
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.598
CLV_PCSK_SKI1_1	17	21	PF00082	0.442
CLV_PCSK_SKI1_1	177	181	PF00082	0.359
CLV_PCSK_SKI1_1	373	377	PF00082	0.521
CLV_PCSK_SKI1_1	465	469	PF00082	0.345
CLV_PCSK_SKI1_1	483	487	PF00082	0.301
CLV_PCSK_SKI1_1	511	515	PF00082	0.527
DEG_APCC_DBOX_1	482	490	PF00400	0.563
DEG_SPOP_SBC_1	189	193	PF00917	0.223
DOC_ANK_TNKS_1	625	632	PF00023	0.513
DOC_CKS1_1	591	596	PF01111	0.383
DOC_MAPK_DCC_7	511	520	PF00069	0.336
DOC_MAPK_gen_1	167	175	PF00069	0.517
DOC_MAPK_gen_1	232	243	PF00069	0.526
DOC_MAPK_gen_1	290	298	PF00069	0.335
DOC_MAPK_gen_1	41	47	PF00069	0.450
DOC_MAPK_gen_1	483	491	PF00069	0.462
DOC_MAPK_MEF2A_6	167	175	PF00069	0.472
DOC_MAPK_MEF2A_6	254	263	PF00069	0.492
DOC_MAPK_MEF2A_6	290	298	PF00069	0.297
DOC_MAPK_MEF2A_6	404	412	PF00069	0.583
DOC_MAPK_MEF2A_6	484	493	PF00069	0.476
DOC_MAPK_MEF2A_6	511	520	PF00069	0.288
DOC_MAPK_MEF2A_6	572	581	PF00069	0.423
DOC_PP1_RVXF_1	463	469	PF00149	0.460
DOC_PP2B_LxvP_1	506	509	PF13499	0.425
DOC_PP2B_LxvP_1	577	580	PF13499	0.445
DOC_PP2B_PxIxI_1	515	521	PF00149	0.388
DOC_PP4_FxxP_1	93	96	PF00568	0.310
DOC_PP4_MxPP_1	627	630	PF00568	0.510
DOC_USP7_MATH_1	188	192	PF00917	0.358
DOC_USP7_MATH_1	286	290	PF00917	0.405
DOC_USP7_MATH_1	380	384	PF00917	0.673
DOC_USP7_MATH_1	632	636	PF00917	0.753
DOC_USP7_UBL2_3	13	17	PF12436	0.695
DOC_WW_Pin1_4	234	239	PF00397	0.670
DOC_WW_Pin1_4	491	496	PF00397	0.370
DOC_WW_Pin1_4	590	595	PF00397	0.417
LIG_14-3-3_CanoR_1	373	378	PF00244	0.706
LIG_14-3-3_CanoR_1	445	453	PF00244	0.334
LIG_APCC_ABBA_1	518	523	PF00400	0.365
LIG_BRCT_BRCA1_1	183	187	PF00533	0.455
LIG_BRCT_BRCA1_1	190	194	PF00533	0.484
LIG_Clathr_ClatBox_1	348	352	PF01394	0.560
LIG_Clathr_ClatBox_1	407	411	PF01394	0.504
LIG_Clathr_ClatBox_1	519	523	PF01394	0.372
LIG_deltaCOP1_diTrp_1	411	419	PF00928	0.361
LIG_EH1_1	264	272	PF00400	0.228
LIG_eIF4E_1	265	271	PF01652	0.298
LIG_FHA_1	134	140	PF00498	0.346
LIG_FHA_1	205	211	PF00498	0.363
LIG_FHA_1	21	27	PF00498	0.590
LIG_FHA_1	298	304	PF00498	0.373
LIG_FHA_1	337	343	PF00498	0.712
LIG_FHA_1	433	439	PF00498	0.326
LIG_FHA_1	452	458	PF00498	0.329
LIG_FHA_1	591	597	PF00498	0.307
LIG_FHA_1	639	645	PF00498	0.667
LIG_FHA_1	83	89	PF00498	0.329
LIG_FHA_2	158	164	PF00498	0.361
LIG_FHA_2	191	197	PF00498	0.341
LIG_FHA_2	247	253	PF00498	0.528
LIG_FHA_2	358	364	PF00498	0.762
LIG_FHA_2	400	406	PF00498	0.549
LIG_FHA_2	74	80	PF00498	0.308
LIG_LIR_Gen_1	140	149	PF02991	0.337
LIG_LIR_Gen_1	184	195	PF02991	0.382
LIG_LIR_Gen_1	200	210	PF02991	0.293
LIG_LIR_Gen_1	217	227	PF02991	0.317
LIG_LIR_Gen_1	411	420	PF02991	0.325
LIG_LIR_Gen_1	450	459	PF02991	0.304
LIG_LIR_Gen_1	550	559	PF02991	0.311
LIG_LIR_Gen_1	59	69	PF02991	0.394
LIG_LIR_Gen_1	94	104	PF02991	0.395
LIG_LIR_Nem_3	140	146	PF02991	0.298
LIG_LIR_Nem_3	200	205	PF02991	0.264
LIG_LIR_Nem_3	207	212	PF02991	0.305
LIG_LIR_Nem_3	217	222	PF02991	0.276
LIG_LIR_Nem_3	450	456	PF02991	0.337
LIG_LIR_Nem_3	524	530	PF02991	0.400
LIG_LIR_Nem_3	59	65	PF02991	0.336
LIG_LIR_Nem_3	94	100	PF02991	0.334
LIG_MAD2	484	492	PF02301	0.510
LIG_MLH1_MIPbox_1	191	195	PF16413	0.348
LIG_NRBOX	413	419	PF00104	0.259
LIG_Pex14_2	107	111	PF04695	0.355
LIG_Pex14_2	205	209	PF04695	0.356
LIG_Pex14_2	46	50	PF04695	0.344
LIG_Pex14_2	535	539	PF04695	0.545
LIG_Pex14_2	65	69	PF04695	0.336
LIG_PTB_Apo_2	545	552	PF02174	0.528
LIG_SH2_CRK	143	147	PF00017	0.261
LIG_SH2_CRK	265	269	PF00017	0.399
LIG_SH2_CRK	97	101	PF00017	0.307
LIG_SH2_STAP1	251	255	PF00017	0.620
LIG_SH2_STAP1	265	269	PF00017	0.411
LIG_SH2_STAP1	453	457	PF00017	0.370
LIG_SH2_STAP1	60	64	PF00017	0.332
LIG_SH2_STAP1	616	620	PF00017	0.548
LIG_SH2_STAP1	97	101	PF00017	0.322
LIG_SH2_STAT3	392	395	PF00017	0.665
LIG_SH2_STAT5	157	160	PF00017	0.377
LIG_SH2_STAT5	204	207	PF00017	0.311
LIG_SH2_STAT5	226	229	PF00017	0.485
LIG_SH2_STAT5	406	409	PF00017	0.536
LIG_SH2_STAT5	453	456	PF00017	0.272
LIG_SH2_STAT5	474	477	PF00017	0.528
LIG_SH2_STAT5	92	95	PF00017	0.301
LIG_SH2_STAT5	97	100	PF00017	0.307
LIG_SH3_3	100	106	PF00018	0.387
LIG_SH3_3	219	225	PF00018	0.326
LIG_SH3_3	253	259	PF00018	0.530
LIG_SH3_3	365	371	PF00018	0.727
LIG_SH3_3	489	495	PF00018	0.282
LIG_SH3_3	510	516	PF00018	0.330
LIG_SH3_3	588	594	PF00018	0.324
LIG_SUMO_SIM_anti_2	217	224	PF11976	0.374
LIG_SUMO_SIM_anti_2	239	245	PF11976	0.598
LIG_SUMO_SIM_anti_2	306	311	PF11976	0.306
LIG_SUMO_SIM_anti_2	78	85	PF11976	0.334
LIG_SUMO_SIM_par_1	299	304	PF11976	0.345
LIG_SUMO_SIM_par_1	593	599	PF11976	0.340
LIG_TRAF2_1	643	646	PF00917	0.665
LIG_TYR_ITIM	141	146	PF00017	0.305
LIG_TYR_ITIM	263	268	PF00017	0.371
LIG_TYR_ITIM	95	100	PF00017	0.316
LIG_UBA3_1	503	511	PF00899	0.384
LIG_WRC_WIRS_1	558	563	PF05994	0.360
MOD_CK1_1	382	388	PF00069	0.645
MOD_CK1_1	434	440	PF00069	0.327
MOD_CK1_1	557	563	PF00069	0.346
MOD_CK1_1	635	641	PF00069	0.708
MOD_CK1_1	7	13	PF00069	0.666
MOD_CK1_1	78	84	PF00069	0.274
MOD_CK2_1	157	163	PF00069	0.404
MOD_CK2_1	190	196	PF00069	0.524
MOD_CK2_1	246	252	PF00069	0.511
MOD_CK2_1	357	363	PF00069	0.737
MOD_CK2_1	380	386	PF00069	0.640
MOD_GlcNHglycan	149	152	PF01048	0.338
MOD_GlcNHglycan	290	293	PF01048	0.582
MOD_GlcNHglycan	363	367	PF01048	0.557
MOD_GlcNHglycan	449	452	PF01048	0.310
MOD_GlcNHglycan	9	12	PF01048	0.469
MOD_GSK3_1	133	140	PF00069	0.349
MOD_GSK3_1	177	184	PF00069	0.346
MOD_GSK3_1	297	304	PF00069	0.363
MOD_GSK3_1	358	365	PF00069	0.741
MOD_GSK3_1	376	383	PF00069	0.685
MOD_GSK3_1	430	437	PF00069	0.413
MOD_GSK3_1	443	450	PF00069	0.361
MOD_GSK3_1	50	57	PF00069	0.327
MOD_GSK3_1	586	593	PF00069	0.370
MOD_GSK3_1	64	71	PF00069	0.308
MOD_GSK3_1	78	85	PF00069	0.270
MOD_GSK3_1	91	98	PF00069	0.307
MOD_N-GLC_1	286	291	PF02516	0.565
MOD_N-GLC_1	373	378	PF02516	0.466
MOD_N-GLC_1	431	436	PF02516	0.553
MOD_N-GLC_1	547	552	PF02516	0.435
MOD_NEK2_1	145	150	PF00069	0.333
MOD_NEK2_1	182	187	PF00069	0.377
MOD_NEK2_1	190	195	PF00069	0.414
MOD_NEK2_1	244	249	PF00069	0.517
MOD_NEK2_1	303	308	PF00069	0.320
MOD_NEK2_1	430	435	PF00069	0.306
MOD_NEK2_1	50	55	PF00069	0.299
MOD_NEK2_1	538	543	PF00069	0.519
MOD_NEK2_1	64	69	PF00069	0.333
MOD_NEK2_1	73	78	PF00069	0.338
MOD_NEK2_2	137	142	PF00069	0.283
MOD_NEK2_2	399	404	PF00069	0.589
MOD_NEK2_2	547	552	PF00069	0.496
MOD_OFUCOSY	585	590	PF10250	0.505
MOD_PIKK_1	18	24	PF00454	0.637
MOD_PIKK_1	380	386	PF00454	0.769
MOD_PIKK_1	444	450	PF00454	0.344
MOD_PIKK_1	64	70	PF00454	0.305
MOD_PKA_1	444	450	PF00069	0.299
MOD_PKA_2	358	364	PF00069	0.751
MOD_PKA_2	444	450	PF00069	0.421
MOD_PKA_2	620	626	PF00069	0.513
MOD_Plk_1	373	379	PF00069	0.668
MOD_Plk_1	431	437	PF00069	0.321
MOD_Plk_1	547	553	PF00069	0.435
MOD_Plk_1	78	84	PF00069	0.260
MOD_Plk_4	157	163	PF00069	0.344
MOD_Plk_4	182	188	PF00069	0.365
MOD_Plk_4	190	196	PF00069	0.436
MOD_Plk_4	215	221	PF00069	0.254
MOD_Plk_4	246	252	PF00069	0.543
MOD_Plk_4	303	309	PF00069	0.360
MOD_Plk_4	4	10	PF00069	0.657
MOD_Plk_4	547	553	PF00069	0.317
MOD_Plk_4	554	560	PF00069	0.295
MOD_Plk_4	596	602	PF00069	0.291
MOD_Plk_4	78	84	PF00069	0.320
MOD_Plk_4	95	101	PF00069	0.369
MOD_ProDKin_1	234	240	PF00069	0.669
MOD_ProDKin_1	491	497	PF00069	0.370
MOD_ProDKin_1	590	596	PF00069	0.385
MOD_SUMO_rev_2	645	649	PF00179	0.691
TRG_DiLeu_BaEn_1	344	349	PF01217	0.560
TRG_DiLeu_BaLyEn_6	257	262	PF01217	0.606
TRG_ENDOCYTIC_2	143	146	PF00928	0.281
TRG_ENDOCYTIC_2	265	268	PF00928	0.354
TRG_ENDOCYTIC_2	422	425	PF00928	0.321
TRG_ENDOCYTIC_2	453	456	PF00928	0.303
TRG_ENDOCYTIC_2	616	619	PF00928	0.516
TRG_ENDOCYTIC_2	92	95	PF00928	0.307
TRG_ENDOCYTIC_2	97	100	PF00928	0.317
TRG_ER_diArg_1	166	169	PF00400	0.559
TRG_ER_diArg_1	231	233	PF00400	0.581
TRG_ER_diArg_1	40	42	PF00400	0.462
TRG_ER_diArg_1	575	577	PF00400	0.374
TRG_ER_diArg_1	626	629	PF00400	0.619
TRG_Pf-PMV_PEXEL_1	24	28	PF00026	0.418

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6G0	Leptomonas seymouri	27%	100%
A0A0N1HT40	Leptomonas seymouri	28%	100%
A0A0N1HZC2	Leptomonas seymouri	46%	100%
A0A0N1IKC5	Leptomonas seymouri	27%	100%
A0A0N1PB63	Leptomonas seymouri	68%	100%
A0A0N1PD04	Leptomonas seymouri	23%	100%
A0A0N1PFR4	Leptomonas seymouri	27%	100%
A0A0S4JR45	Bodo saltans	24%	100%
A0A1X0NKK0	Trypanosomatidae	50%	100%
A0A1X0NM09	Trypanosomatidae	49%	100%
A0A1X0NRW5	Trypanosomatidae	25%	95%
A0A1X0NV13	Trypanosomatidae	28%	100%
A0A1X0NV19	Trypanosomatidae	28%	100%
A0A1X0NV27	Trypanosomatidae	29%	100%
A0A1X0NVH8	Trypanosomatidae	25%	100%
A0A1X0NVM7	Trypanosomatidae	28%	100%
A0A1X0NWQ1	Trypanosomatidae	27%	100%
A0A1X0NZE6	Trypanosomatidae	27%	100%
A0A1X0NZU2	Trypanosomatidae	25%	100%
A0A1X0NZU5	Trypanosomatidae	27%	100%
A0A1X0NZW1	Trypanosomatidae	27%	100%
A0A1X0P0M7	Trypanosomatidae	27%	100%
A0A381MMW5	Leishmania infantum	26%	100%
A0A3Q8I7Y9	Leishmania donovani	27%	90%
A0A3Q8IEC4	Leishmania donovani	26%	100%
A0A3Q8IF95	Leishmania donovani	51%	100%
A0A3Q8IIT5	Leishmania donovani	27%	100%
A0A3Q8ISY9	Leishmania donovani	25%	100%
A0A3R7KKN8	Trypanosoma rangeli	26%	100%
A0A3R7MAQ7	Trypanosoma rangeli	22%	94%
A0A3R7N3S6	Trypanosoma rangeli	22%	100%
A0A3R7N415	Trypanosoma rangeli	25%	100%
A0A3R7N921	Trypanosoma rangeli	29%	100%
A0A3R7R443	Trypanosoma rangeli	25%	100%
A0A3S7WRJ4	Leishmania donovani	27%	100%
A0A3S7WRJ5	Leishmania donovani	26%	100%
A0A3S7WRL4	Leishmania donovani	28%	99%
A0A3S7WRS3	Leishmania donovani	22%	100%
A0A3S7WSR4	Leishmania donovani	25%	96%
A0A3S7X2G0	Leishmania donovani	26%	100%
A0A3S7X2K5	Leishmania donovani	26%	100%
A0A3S7XB11	Leishmania donovani	48%	100%
A0A422MSE4	Trypanosoma rangeli	29%	100%
A0A422MSP6	Trypanosoma rangeli	26%	100%
A0A422MST9	Trypanosoma rangeli	26%	100%
A0A422MU68	Trypanosoma rangeli	48%	100%
A4H6J0	Leishmania braziliensis	26%	100%
A4H6J1	Leishmania braziliensis	28%	100%
A4H6J3	Leishmania braziliensis	27%	95%
A4H6Q5	Leishmania braziliensis	22%	100%
A4HC19	Leishmania braziliensis	76%	100%
A4HHG2	Leishmania braziliensis	26%	99%
A4HHG3	Leishmania braziliensis	27%	100%
A4HHG4	Leishmania braziliensis	27%	100%
A4HJW3	Leishmania braziliensis	25%	100%
A4HPE2	Leishmania braziliensis	48%	100%
A4HUX5	Leishmania infantum	27%	100%
A4HUX6	Leishmania infantum	26%	100%
A4HUX7	Leishmania infantum	27%	99%
A4HUX8	Leishmania infantum	27%	94%
A4HV40	Leishmania infantum	22%	100%
A4HZF5	Leishmania infantum	51%	100%
A4HZJ4	Leishmania infantum	99%	100%
A4I4L2	Leishmania infantum	26%	100%
A4I7C5	Leishmania infantum	25%	100%
A4ICI3	Leishmania infantum	48%	98%
C9ZL97	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZL98	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZL99	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZLA0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZLA1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
C9ZTR5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
C9ZTR6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZTR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
C9ZTR8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZTR9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZTS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZUT6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A7B1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0A7H1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0AAQ2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	97%
E8NHE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AE01	Leishmania major	26%	98%
E9AE09	Leishmania major	25%	100%
E9AE10	Leishmania major	25%	100%
E9AE11	Leishmania major	26%	100%
E9AGK5	Leishmania infantum	25%	96%
E9AHJ0	Leishmania infantum	26%	100%
E9AHJ1	Leishmania infantum	26%	100%
E9ALS2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ALS3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ANL0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ANL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ANL2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	97%
E9ANS1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9APJ3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	98%
E9AT53	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	97%
E9AVF1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	99%
E9AVF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
E9B2B8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	99%
Q4Q1E4	Leishmania major	48%	99%
Q4Q5T8	Leishmania major	25%	100%
Q4QC27	Leishmania major	95%	100%
Q4QC28	Leishmania major	50%	97%
Q4QFY5	Leishmania major	25%	96%
Q4QGU8	Leishmania major	23%	100%
Q4QH10	Leishmania major	26%	95%
Q4QH11	Leishmania major	27%	92%
Q4QH12	Leishmania major	27%	92%
Q4QH13	Leishmania major	26%	91%
Q4QH14	Leishmania major	26%	100%
Q4QH15	Leishmania major	26%	97%
V5B647	Trypanosoma cruzi	29%	100%
V5B983	Trypanosoma cruzi	28%	100%
V5BBB1	Trypanosoma cruzi	24%	100%
V5BFV8	Trypanosoma cruzi	26%	99%
V5BQY6	Trypanosoma cruzi	25%	94%
V5BVP0	Trypanosoma cruzi	27%	100%
V5DT25	Trypanosoma cruzi	27%	100%