Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WWT1_LEIDO

TriTrypDb:

LdBPK_211500.1 , LdCL_210020500 , LDHU3_21.1780

Length:

498

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Show entries

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	6
GO:0042995	cell projection	2	6
GO:0043226	organelle	2	6
GO:0043227	membrane-bounded organelle	3	6
GO:0110165	cellular anatomical entity	1	6
GO:0120025	plasma membrane bounded cell projection	3	6

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Expansion

Sequence features

A0A3S7WWT1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWT1

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	342	346	PF00656	0.740
CLV_C14_Caspase3-7	399	403	PF00656	0.630
CLV_C14_Caspase3-7	421	425	PF00656	0.643
CLV_C14_Caspase3-7	486	490	PF00656	0.593
CLV_NRD_NRD_1	201	203	PF00675	0.524
CLV_NRD_NRD_1	205	207	PF00675	0.518
CLV_NRD_NRD_1	213	215	PF00675	0.510
CLV_NRD_NRD_1	97	99	PF00675	0.385
CLV_PCSK_KEX2_1	201	203	PF00082	0.524
CLV_PCSK_KEX2_1	205	207	PF00082	0.518

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4HBY1	Leishmania braziliensis	55%	97%
A4HZC3	Leishmania infantum	99%	100%
E9AVB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	98%
Q4QC70	Leishmania major	84%	100%

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