LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WWM3_LEIDO
TriTrypDb:
LdBPK_211570.1 , LdCL_210021200 , LDHU3_21.1860
Length:
161

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 25
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 6, no: 4
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A0A3S7WWM3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWM3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 10 12 PF00675 0.604
CLV_NRD_NRD_1 93 95 PF00675 0.685
CLV_PCSK_KEX2_1 10 12 PF00082 0.604
CLV_PCSK_KEX2_1 92 94 PF00082 0.713
CLV_PCSK_SKI1_1 102 106 PF00082 0.702
CLV_PCSK_SKI1_1 117 121 PF00082 0.602
DEG_APCC_DBOX_1 131 139 PF00400 0.389
DEG_Nend_UBRbox_1 1 4 PF02207 0.814
LIG_14-3-3_CanoR_1 21 30 PF00244 0.666
LIG_14-3-3_CanoR_1 5 9 PF00244 0.812
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HSR8 Leptomonas seymouri 61% 100%
A0A0S4JJA7 Bodo saltans 46% 100%
A0A1X0NXY8 Trypanosomatidae 39% 100%
A0A3R7KIY1 Trypanosoma rangeli 44% 100%
A4HBY8 Leishmania braziliensis 67% 100%
A4HZD0 Leishmania infantum 100% 100%
D0A154 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AVB7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
Q4QC63 Leishmania major 91% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS