Qc-SNARE_protein_putative/GeneDB:LmjF.21.0560

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Qc-SNARE protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WWG9_LEIDO

TriTrypDb:

LdBPK_210620.1 , LdCL_210011200 , LDHU3_21.0670

Length:

Annotations

Annotations by Jardim et al.

Vesicle mediated transport, Qc-SNARE

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

Phosphorylation

Amastigote: 24, 28, 4

Expansion

Sequence features

A0A3S7WWG9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWG9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	61	63	PF00675	0.422
CLV_PCSK_KEX2_1	61	63	PF00082	0.392
DEG_Nend_UBRbox_2	1	3	PF02207	0.732
DOC_MAPK_MEF2A_6	77	86	PF00069	0.400
DOC_USP7_MATH_1	57	61	PF00917	0.636
LIG_14-3-3_CanoR_1	77	83	PF00244	0.349
LIG_EH1_1	79	87	PF00400	0.443
LIG_eIF4E_1	80	86	PF01652	0.487
LIG_FHA_2	54	60	PF00498	0.656
LIG_GBD_Chelix_1	86	94	PF00786	0.402
LIG_PCNA_yPIPBox_3	61	71	PF02747	0.608
LIG_PDZ_Class_2	91	96	PF00595	0.344
LIG_SH2_CRK	80	84	PF00017	0.400
LIG_SH2_STAP1	31	35	PF00017	0.595
LIG_SH2_STAP1	80	84	PF00017	0.443
LIG_SH2_STAT3	31	34	PF00017	0.647
LIG_SUMO_SIM_anti_2	81	87	PF11976	0.396
MOD_CK2_1	53	59	PF00069	0.627
MOD_GSK3_1	21	28	PF00069	0.586
MOD_GSK3_1	53	60	PF00069	0.670
MOD_N-GLC_1	51	56	PF02516	0.472
MOD_NEK2_1	1	6	PF00069	0.696
MOD_NEK2_1	21	26	PF00069	0.487
MOD_PIKK_1	10	16	PF00454	0.647
MOD_PKA_2	71	77	PF00069	0.663
MOD_Plk_1	1	7	PF00069	0.742
MOD_Plk_4	21	27	PF00069	0.573
MOD_Plk_4	78	84	PF00069	0.396
TRG_ENDOCYTIC_2	80	83	PF00928	0.400

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFZ7	Leptomonas seymouri	86%	99%
A0A0S4JF09	Bodo saltans	54%	93%
A0A1X0NXH2	Trypanosomatidae	66%	91%
A4HBQ3	Leishmania braziliensis	89%	100%
A4HZ55	Leishmania infantum	100%	100%
D0A1Q5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	99%
E9AV23	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4QCF9	Leishmania major	98%	100%