LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WWF0_LEIDO
TriTrypDb:
LdBPK_210660.1 * , LdCL_210011600 , LDHU3_21.0710
Length:
536

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WWF0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWF0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 27 29 PF00675 0.553
CLV_NRD_NRD_1 4 6 PF00675 0.551
CLV_NRD_NRD_1 68 70 PF00675 0.559
CLV_NRD_NRD_1 95 97 PF00675 0.462
CLV_PCSK_KEX2_1 27 29 PF00082 0.553
CLV_PCSK_KEX2_1 4 6 PF00082 0.579
CLV_PCSK_KEX2_1 67 69 PF00082 0.565
CLV_PCSK_SKI1_1 386 390 PF00082 0.508
CLV_PCSK_SKI1_1 402 406 PF00082 0.413
CLV_PCSK_SKI1_1 422 426 PF00082 0.317
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IM65 Leptomonas seymouri 38% 88%
A4HBQ7 Leishmania braziliensis 76% 100%
A4HZ59 Leishmania infantum 100% 100%
E9AV27 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4QCF5 Leishmania major 93% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS