LeishMANIAdb
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Phosphoglycan beta 1,3 galactosyltransferase 4

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phosphoglycan beta 1,3 galactosyltransferase 4
Gene product:
phosphoglycan beta 1,3 galactosyltransferase 4 (fragment)
Species:
Leishmania donovani
UniProt:
A0A3S7WWA6_LEIDO
TriTrypDb:
LdBPK_360010.1 , LdCL_210005000 , LDHU3_31.5600
Length:
814

Annotations

LeishMANIAdb annotations

Phosphoglycan beta 1,3 galactosyltransferase (required for proper protective coat formation). Probably part of a much larger group. Expanded in Leishmaniids. Localization: Golgi (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 52
NetGPI no yes: 0, no: 52
Cellular components
Term Name Level Count
GO:0016020 membrane 2 53
GO:0110165 cellular anatomical entity 1 53
GO:0000139 Golgi membrane 5 14
GO:0031090 organelle membrane 3 14
GO:0098588 bounding membrane of organelle 4 14

Expansion

Sequence features

A0A3S7WWA6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WWA6

Function

Biological processes
Term Name Level Count
GO:0006486 protein glycosylation 4 53
GO:0006807 nitrogen compound metabolic process 2 53
GO:0008152 metabolic process 1 53
GO:0019538 protein metabolic process 3 53
GO:0036211 protein modification process 4 53
GO:0043170 macromolecule metabolic process 3 53
GO:0043412 macromolecule modification 4 53
GO:0043413 macromolecule glycosylation 3 53
GO:0044238 primary metabolic process 2 53
GO:0070085 glycosylation 2 53
GO:0071704 organic substance metabolic process 2 53
GO:1901564 organonitrogen compound metabolic process 3 53
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 53
GO:0016740 transferase activity 2 53
GO:0016757 glycosyltransferase activity 3 53
GO:0016758 hexosyltransferase activity 4 53
GO:0008194 UDP-glycosyltransferase activity 4 14

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 180 184 PF00656 0.359
CLV_C14_Caspase3-7 435 439 PF00656 0.355
CLV_C14_Caspase3-7 662 666 PF00656 0.283
CLV_NRD_NRD_1 149 151 PF00675 0.634
CLV_NRD_NRD_1 284 286 PF00675 0.659
CLV_NRD_NRD_1 400 402 PF00675 0.667
CLV_NRD_NRD_1 490 492 PF00675 0.574
CLV_NRD_NRD_1 611 613 PF00675 0.555
CLV_NRD_NRD_1 682 684 PF00675 0.517
CLV_NRD_NRD_1 93 95 PF00675 0.454
CLV_PCSK_KEX2_1 106 108 PF00082 0.408
CLV_PCSK_KEX2_1 138 140 PF00082 0.777
CLV_PCSK_KEX2_1 149 151 PF00082 0.594
CLV_PCSK_KEX2_1 284 286 PF00082 0.655
CLV_PCSK_KEX2_1 314 316 PF00082 0.542
CLV_PCSK_KEX2_1 400 402 PF00082 0.665
CLV_PCSK_KEX2_1 611 613 PF00082 0.504
CLV_PCSK_KEX2_1 674 676 PF00082 0.601
CLV_PCSK_KEX2_1 682 684 PF00082 0.532
CLV_PCSK_KEX2_1 730 732 PF00082 0.548
CLV_PCSK_KEX2_1 93 95 PF00082 0.454
CLV_PCSK_PC1ET2_1 106 108 PF00082 0.409
CLV_PCSK_PC1ET2_1 138 140 PF00082 0.654
CLV_PCSK_PC1ET2_1 314 316 PF00082 0.516
CLV_PCSK_PC1ET2_1 674 676 PF00082 0.545
CLV_PCSK_PC1ET2_1 730 732 PF00082 0.548
CLV_PCSK_SKI1_1 106 110 PF00082 0.252
CLV_PCSK_SKI1_1 401 405 PF00082 0.589
CLV_PCSK_SKI1_1 563 567 PF00082 0.546
CLV_Separin_Metazoa 269 273 PF03568 0.345
DEG_Nend_UBRbox_1 1 4 PF02207 0.681
DEG_SCF_FBW7_1 452 459 PF00400 0.458
DOC_CKS1_1 453 458 PF01111 0.461
DOC_CYCLIN_yCln2_LP_2 249 255 PF00134 0.335
DOC_CYCLIN_yCln2_LP_2 450 456 PF00134 0.506
DOC_MAPK_DCC_7 572 581 PF00069 0.349
DOC_MAPK_gen_1 106 114 PF00069 0.537
DOC_MAPK_gen_1 298 307 PF00069 0.387
DOC_MAPK_gen_1 496 503 PF00069 0.355
DOC_MAPK_gen_1 693 702 PF00069 0.273
DOC_MAPK_HePTP_8 104 116 PF00069 0.439
DOC_MAPK_JIP1_4 298 304 PF00069 0.364
DOC_MAPK_MEF2A_6 106 114 PF00069 0.575
DOC_MAPK_MEF2A_6 480 487 PF00069 0.432
DOC_MAPK_MEF2A_6 536 545 PF00069 0.302
DOC_MAPK_MEF2A_6 572 581 PF00069 0.338
DOC_MAPK_MEF2A_6 642 649 PF00069 0.297
DOC_MAPK_NFAT4_5 480 488 PF00069 0.333
DOC_PP1_RVXF_1 500 506 PF00149 0.379
DOC_PP1_RVXF_1 514 521 PF00149 0.352
DOC_PP1_RVXF_1 588 594 PF00149 0.307
DOC_PP1_RVXF_1 694 700 PF00149 0.312
DOC_PP2B_LxvP_1 450 453 PF13499 0.506
DOC_PP2B_LxvP_1 543 546 PF13499 0.310
DOC_PP4_FxxP_1 153 156 PF00568 0.416
DOC_PP4_FxxP_1 706 709 PF00568 0.269
DOC_SPAK_OSR1_1 107 111 PF12202 0.413
DOC_SPAK_OSR1_1 128 132 PF12202 0.371
DOC_USP7_MATH_1 148 152 PF00917 0.413
DOC_USP7_MATH_1 222 226 PF00917 0.462
DOC_USP7_MATH_1 241 245 PF00917 0.496
DOC_USP7_MATH_1 256 260 PF00917 0.348
DOC_USP7_MATH_1 289 293 PF00917 0.468
DOC_USP7_MATH_1 37 41 PF00917 0.716
DOC_USP7_MATH_1 371 375 PF00917 0.349
DOC_USP7_MATH_1 635 639 PF00917 0.367
DOC_USP7_MATH_1 92 96 PF00917 0.648
DOC_USP7_UBL2_3 492 496 PF12436 0.353
DOC_USP7_UBL2_3 669 673 PF12436 0.278
DOC_USP7_UBL2_3 720 724 PF12436 0.322
DOC_WW_Pin1_4 152 157 PF00397 0.450
DOC_WW_Pin1_4 24 29 PF00397 0.648
DOC_WW_Pin1_4 418 423 PF00397 0.488
DOC_WW_Pin1_4 438 443 PF00397 0.425
DOC_WW_Pin1_4 452 457 PF00397 0.433
LIG_14-3-3_CanoR_1 149 157 PF00244 0.438
LIG_14-3-3_CanoR_1 169 177 PF00244 0.381
LIG_14-3-3_CanoR_1 427 431 PF00244 0.408
LIG_14-3-3_CanoR_1 433 437 PF00244 0.410
LIG_14-3-3_CanoR_1 480 484 PF00244 0.355
LIG_14-3-3_CanoR_1 502 506 PF00244 0.311
LIG_14-3-3_CanoR_1 563 570 PF00244 0.427
LIG_14-3-3_CanoR_1 779 785 PF00244 0.348
LIG_14-3-3_CanoR_1 93 100 PF00244 0.657
LIG_Actin_WH2_2 538 555 PF00022 0.276
LIG_APCC_ABBA_1 159 164 PF00400 0.346
LIG_BRCT_BRCA1_1 84 88 PF00533 0.623
LIG_Clathr_ClatBox_1 185 189 PF01394 0.334
LIG_EH_1 618 622 PF12763 0.336
LIG_FHA_1 128 134 PF00498 0.463
LIG_FHA_1 180 186 PF00498 0.360
LIG_FHA_1 195 201 PF00498 0.488
LIG_FHA_1 259 265 PF00498 0.395
LIG_FHA_1 338 344 PF00498 0.330
LIG_FHA_1 361 367 PF00498 0.357
LIG_FHA_1 426 432 PF00498 0.374
LIG_FHA_1 438 444 PF00498 0.424
LIG_FHA_1 564 570 PF00498 0.324
LIG_FHA_1 576 582 PF00498 0.459
LIG_FHA_2 163 169 PF00498 0.346
LIG_FHA_2 326 332 PF00498 0.409
LIG_FHA_2 370 376 PF00498 0.449
LIG_FHA_2 781 787 PF00498 0.339
LIG_IBAR_NPY_1 634 636 PF08397 0.303
LIG_LIR_Apic_2 151 156 PF02991 0.415
LIG_LIR_Apic_2 416 422 PF02991 0.345
LIG_LIR_Apic_2 504 508 PF02991 0.426
LIG_LIR_Gen_1 155 161 PF02991 0.462
LIG_LIR_Gen_1 206 217 PF02991 0.372
LIG_LIR_Gen_1 482 488 PF02991 0.368
LIG_LIR_Gen_1 539 549 PF02991 0.396
LIG_LIR_Gen_1 622 632 PF02991 0.282
LIG_LIR_Gen_1 643 651 PF02991 0.373
LIG_LIR_Gen_1 698 706 PF02991 0.357
LIG_LIR_Nem_3 155 160 PF02991 0.430
LIG_LIR_Nem_3 206 212 PF02991 0.371
LIG_LIR_Nem_3 325 329 PF02991 0.467
LIG_LIR_Nem_3 406 411 PF02991 0.371
LIG_LIR_Nem_3 482 487 PF02991 0.331
LIG_LIR_Nem_3 526 531 PF02991 0.386
LIG_LIR_Nem_3 539 545 PF02991 0.368
LIG_LIR_Nem_3 622 627 PF02991 0.294
LIG_LIR_Nem_3 643 647 PF02991 0.393
LIG_LIR_Nem_3 698 702 PF02991 0.359
LIG_NRBOX 111 117 PF00104 0.300
LIG_NRBOX 627 633 PF00104 0.335
LIG_NRP_CendR_1 813 814 PF00754 0.586
LIG_Pex14_2 153 157 PF04695 0.419
LIG_PTB_Apo_2 208 215 PF02174 0.378
LIG_PTB_Apo_2 791 798 PF02174 0.275
LIG_PTB_Phospho_1 208 214 PF10480 0.374
LIG_PTB_Phospho_1 791 797 PF10480 0.271
LIG_RPA_C_Fungi 678 690 PF08784 0.314
LIG_SH2_NCK_1 376 380 PF00017 0.470
LIG_SH2_NCK_1 782 786 PF00017 0.407
LIG_SH2_PTP2 644 647 PF00017 0.287
LIG_SH2_STAP1 214 218 PF00017 0.509
LIG_SH2_STAP1 523 527 PF00017 0.550
LIG_SH2_STAP1 595 599 PF00017 0.357
LIG_SH2_STAP1 651 655 PF00017 0.351
LIG_SH2_STAT3 280 283 PF00017 0.431
LIG_SH2_STAT3 595 598 PF00017 0.348
LIG_SH2_STAT5 347 350 PF00017 0.478
LIG_SH2_STAT5 397 400 PF00017 0.419
LIG_SH2_STAT5 464 467 PF00017 0.368
LIG_SH2_STAT5 525 528 PF00017 0.379
LIG_SH2_STAT5 533 536 PF00017 0.341
LIG_SH2_STAT5 542 545 PF00017 0.427
LIG_SH2_STAT5 548 551 PF00017 0.355
LIG_SH2_STAT5 607 610 PF00017 0.289
LIG_SH2_STAT5 644 647 PF00017 0.429
LIG_SH2_STAT5 714 717 PF00017 0.547
LIG_SH2_STAT5 782 785 PF00017 0.456
LIG_SH3_3 450 456 PF00018 0.589
LIG_SH3_3 526 532 PF00018 0.430
LIG_SH3_3 571 577 PF00018 0.466
LIG_SH3_3 614 620 PF00018 0.342
LIG_SH3_3 706 712 PF00018 0.348
LIG_SH3_4 492 499 PF00018 0.414
LIG_SUMO_SIM_anti_2 698 704 PF11976 0.286
LIG_TYR_ITIM 327 332 PF00017 0.443
MOD_CDC14_SPxK_1 27 30 PF00782 0.505
MOD_CDK_SPxK_1 24 30 PF00069 0.513
MOD_CK1_1 127 133 PF00069 0.520
MOD_CK1_1 155 161 PF00069 0.478
MOD_CK1_1 292 298 PF00069 0.553
MOD_CK1_1 356 362 PF00069 0.642
MOD_CK1_1 393 399 PF00069 0.349
MOD_CK1_1 429 435 PF00069 0.471
MOD_CK1_1 65 71 PF00069 0.607
MOD_CK2_1 162 168 PF00069 0.445
MOD_CK2_1 325 331 PF00069 0.489
MOD_CK2_1 33 39 PF00069 0.579
MOD_CK2_1 369 375 PF00069 0.578
MOD_CK2_1 53 59 PF00069 0.537
MOD_CK2_1 780 786 PF00069 0.367
MOD_Cter_Amidation 811 814 PF01082 0.363
MOD_GlcNHglycan 215 218 PF01048 0.574
MOD_GlcNHglycan 243 246 PF01048 0.618
MOD_GlcNHglycan 35 38 PF01048 0.627
MOD_GlcNHglycan 39 42 PF01048 0.612
MOD_GlcNHglycan 392 395 PF01048 0.387
MOD_GlcNHglycan 446 449 PF01048 0.521
MOD_GlcNHglycan 468 471 PF01048 0.527
MOD_GlcNHglycan 65 68 PF01048 0.599
MOD_GlcNHglycan 810 813 PF01048 0.407
MOD_GlcNHglycan 94 97 PF01048 0.543
MOD_GSK3_1 137 144 PF00069 0.574
MOD_GSK3_1 148 155 PF00069 0.579
MOD_GSK3_1 177 184 PF00069 0.479
MOD_GSK3_1 222 229 PF00069 0.610
MOD_GSK3_1 33 40 PF00069 0.630
MOD_GSK3_1 353 360 PF00069 0.595
MOD_GSK3_1 425 432 PF00069 0.520
MOD_GSK3_1 444 451 PF00069 0.511
MOD_GSK3_1 452 459 PF00069 0.412
MOD_GSK3_1 62 69 PF00069 0.568
MOD_GSK3_1 753 760 PF00069 0.420
MOD_N-GLC_1 210 215 PF02516 0.468
MOD_N-GLC_1 230 235 PF02516 0.473
MOD_N-GLC_1 337 342 PF02516 0.393
MOD_N-GLC_1 563 568 PF02516 0.411
MOD_N-GLC_1 636 641 PF02516 0.335
MOD_N-GLC_1 744 749 PF02516 0.442
MOD_NEK2_1 170 175 PF00069 0.485
MOD_NEK2_1 240 245 PF00069 0.544
MOD_NEK2_1 501 506 PF00069 0.422
MOD_NEK2_1 565 570 PF00069 0.589
MOD_NEK2_2 194 199 PF00069 0.623
MOD_PIKK_1 132 138 PF00454 0.539
MOD_PIKK_1 170 176 PF00454 0.434
MOD_PIKK_1 287 293 PF00454 0.532
MOD_PIKK_1 511 517 PF00454 0.423
MOD_PIKK_1 594 600 PF00454 0.338
MOD_PIKK_1 744 750 PF00454 0.419
MOD_PIKK_1 753 759 PF00454 0.393
MOD_PIKK_1 99 105 PF00454 0.459
MOD_PKA_1 491 497 PF00069 0.591
MOD_PKA_2 127 133 PF00069 0.469
MOD_PKA_2 13 19 PF00069 0.617
MOD_PKA_2 141 147 PF00069 0.536
MOD_PKA_2 148 154 PF00069 0.524
MOD_PKA_2 168 174 PF00069 0.445
MOD_PKA_2 223 229 PF00069 0.599
MOD_PKA_2 292 298 PF00069 0.571
MOD_PKA_2 353 359 PF00069 0.492
MOD_PKA_2 426 432 PF00069 0.603
MOD_PKA_2 479 485 PF00069 0.436
MOD_PKA_2 501 507 PF00069 0.358
MOD_PKA_2 681 687 PF00069 0.328
MOD_PKA_2 92 98 PF00069 0.532
MOD_Plk_1 203 209 PF00069 0.468
MOD_Plk_1 210 216 PF00069 0.442
MOD_Plk_1 230 236 PF00069 0.470
MOD_Plk_1 636 642 PF00069 0.343
MOD_Plk_2-3 353 359 PF00069 0.496
MOD_Plk_4 181 187 PF00069 0.631
MOD_Plk_4 322 328 PF00069 0.548
MOD_Plk_4 393 399 PF00069 0.397
MOD_Plk_4 426 432 PF00069 0.455
MOD_Plk_4 479 485 PF00069 0.416
MOD_Plk_4 695 701 PF00069 0.479
MOD_Plk_4 758 764 PF00069 0.424
MOD_ProDKin_1 152 158 PF00069 0.537
MOD_ProDKin_1 24 30 PF00069 0.546
MOD_ProDKin_1 418 424 PF00069 0.609
MOD_ProDKin_1 438 444 PF00069 0.508
MOD_ProDKin_1 452 458 PF00069 0.520
MOD_SUMO_rev_2 486 494 PF00179 0.404
MOD_SUMO_rev_2 646 656 PF00179 0.297
MOD_SUMO_rev_2 722 732 PF00179 0.343
TRG_DiLeu_BaEn_1 181 186 PF01217 0.411
TRG_DiLeu_BaEn_1 728 733 PF01217 0.363
TRG_DiLeu_BaLyEn_6 609 614 PF01217 0.339
TRG_DiLeu_LyEn_5 728 733 PF01217 0.360
TRG_ENDOCYTIC_2 329 332 PF00928 0.453
TRG_ENDOCYTIC_2 525 528 PF00928 0.564
TRG_ENDOCYTIC_2 542 545 PF00928 0.452
TRG_ENDOCYTIC_2 644 647 PF00928 0.490
TRG_ER_diArg_1 284 286 PF00400 0.577
TRG_ER_diArg_1 400 402 PF00400 0.565
TRG_ER_diArg_1 611 613 PF00400 0.387
TRG_ER_diArg_1 682 685 PF00400 0.398
TRG_ER_diArg_1 92 94 PF00400 0.567
TRG_NLS_MonoExtN_4 493 500 PF00514 0.439
TRG_NLS_MonoExtN_4 672 677 PF00514 0.343
TRG_Pf-PMV_PEXEL_1 199 203 PF00026 0.439
TRG_Pf-PMV_PEXEL_1 611 615 PF00026 0.473
TRG_Pf-PMV_PEXEL_1 658 662 PF00026 0.298
TRG_Pf-PMV_PEXEL_1 731 735 PF00026 0.377

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IGN9 Leishmania donovani 100% 100%
A0A3S5H4Y6 Leishmania donovani 41% 100%
A0A3S5H4Y9 Leishmania donovani 31% 100%
A0A3S7WT86 Leishmania donovani 37% 100%
A0A451EJD9 Leishmania donovani 81% 100%
A0A451EJF4 Leishmania donovani 39% 100%
A0A451EJF6 Leishmania donovani 39% 100%
A0A451EJF8 Leishmania donovani 38% 100%
A0A451EJF9 Leishmania donovani 40% 94%
A4H3A9 Leishmania braziliensis 42% 100%
A4H3B4 Leishmania braziliensis 42% 100%
A4H3B6 Leishmania braziliensis 41% 100%
A4H3B8 Leishmania braziliensis 42% 100%
A4H3B9 Leishmania braziliensis 34% 100%
A4H4W8 Leishmania braziliensis 64% 100%
A4HJ20 Leishmania braziliensis 41% 100%
A4HNK3 Leishmania braziliensis 73% 100%
A4HNK6 Leishmania braziliensis 64% 100%
A4HRL9 Leishmania infantum 42% 100%
A4HRM0 Leishmania infantum 40% 100%
A4HRM1 Leishmania infantum 41% 98%
A4HRS1 Leishmania infantum 41% 100%
A4HRS3 Leishmania infantum 31% 100%
A4HRS5 Leishmania infantum 38% 100%
A4HZM0 Leishmania infantum 86% 100%
A4I7C7 Leishmania infantum 85% 100%
A4IAQ2 Leishmania infantum 77% 100%
E9AC91 Leishmania major 41% 100%
E9AC92 Leishmania major 42% 100%
E9AC94 Leishmania major 33% 69%
E9AC95 Leishmania major 37% 100%
E9AC96 Leishmania major 40% 100%
E9AC98 Leishmania major 33% 100%
E9AEH8 Leishmania major 74% 100%
E9AHA6 Leishmania infantum 81% 100%
E9AIP8 Leishmania braziliensis 64% 100%
E9AJI3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 100%
E9AJI4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 100%
E9AJI5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
E9AJI6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
E9ALD6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
E9ASB8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 74% 100%
E9AXX8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 74% 100%
E9B2C0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q5T6 Leishmania major 74% 100%
Q4QCL8 Leishmania major 82% 100%
Q4QFJ3 Leishmania major 37% 100%
Q4QIG9 Leishmania major 83% 100%
Q7YXU9 Leishmania major 81% 100%
Q7YXV1 Leishmania major 83% 100%
Q7YXV2 Leishmania major 82% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS