LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WW87_LEIDO
TriTrypDb:
LdBPK_210140.1 , LdCL_210006300 , LDHU3_21.0150
Length:
151

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WW87
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WW87

PDB structure(s): 7aih_V , 7am2_V , 7ane_V

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 131 133 PF00675 0.399
CLV_NRD_NRD_1 22 24 PF00675 0.439
CLV_NRD_NRD_1 65 67 PF00675 0.407
CLV_PCSK_FUR_1 63 67 PF00082 0.405
CLV_PCSK_KEX2_1 103 105 PF00082 0.503
CLV_PCSK_KEX2_1 143 145 PF00082 0.405
CLV_PCSK_KEX2_1 22 24 PF00082 0.421
CLV_PCSK_KEX2_1 63 65 PF00082 0.392
CLV_PCSK_PC1ET2_1 103 105 PF00082 0.504
CLV_PCSK_PC1ET2_1 143 145 PF00082 0.405
CLV_PCSK_SKI1_1 23 27 PF00082 0.528
DEG_MDM2_SWIB_1 51 58 PF02201 0.354
DEG_Nend_Nbox_1 1 3 PF02207 0.526
DEG_ODPH_VHL_1 138 150 PF01847 0.427
DOC_AGCK_PIF_3 148 151 PF00069 0.467
DOC_MAPK_gen_1 103 110 PF00069 0.433
DOC_MAPK_gen_1 63 73 PF00069 0.400
DOC_PP2B_LxvP_1 138 141 PF13499 0.434
DOC_PP4_MxPP_1 47 50 PF00568 0.366
LIG_14-3-3_CanoR_1 128 134 PF00244 0.547
LIG_14-3-3_CanoR_1 3 7 PF00244 0.682
LIG_FHA_2 111 117 PF00498 0.456
LIG_LIR_Gen_1 52 62 PF02991 0.360
LIG_LIR_Gen_1 84 95 PF02991 0.386
LIG_LIR_Nem_3 145 151 PF02991 0.425
LIG_LIR_Nem_3 52 58 PF02991 0.361
LIG_LIR_Nem_3 84 90 PF02991 0.358
LIG_Pex14_1 40 44 PF04695 0.353
LIG_Pex14_2 51 55 PF04695 0.392
LIG_SH2_CRK 87 91 PF00017 0.352
LIG_SH2_STAT3 31 34 PF00017 0.391
LIG_SH2_STAT5 31 34 PF00017 0.391
LIG_SH3_1 79 85 PF00018 0.351
LIG_SH3_3 22 28 PF00018 0.532
LIG_SH3_3 79 85 PF00018 0.351
MOD_CK2_1 119 125 PF00069 0.411
MOD_NEK2_1 110 115 PF00069 0.449
MOD_NEK2_1 2 7 PF00069 0.602
MOD_NEK2_1 90 95 PF00069 0.381
MOD_PKA_2 110 116 PF00069 0.403
MOD_PKA_2 127 133 PF00069 0.451
MOD_PKA_2 2 8 PF00069 0.478
TRG_ENDOCYTIC_2 87 90 PF00928 0.356
TRG_ER_diArg_1 108 111 PF00400 0.407
TRG_ER_diArg_1 22 24 PF00400 0.421
TRG_ER_diArg_1 62 65 PF00400 0.395
TRG_ER_diArg_1 94 97 PF00400 0.368

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IIX3 Leptomonas seymouri 87% 100%
A0A1X0NXY7 Trypanosomatidae 81% 100%
A0A3R7M8D8 Trypanosoma rangeli 80% 100%
A4HBK7 Leishmania braziliensis 94% 100%
A4HZK9 Leishmania infantum 99% 100%
D0A1K1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 83% 83%
E9AUX6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
Q4QCK6 Leishmania major 99% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS