LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WW50_LEIDO
TriTrypDb:
LdBPK_201460.1 , LdCL_200019300 , LDHU3_20.1830
Length:
930

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WW50
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WW50

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 25 29 PF00656 0.648
CLV_C14_Caspase3-7 702 706 PF00656 0.585
CLV_NRD_NRD_1 117 119 PF00675 0.648
CLV_NRD_NRD_1 342 344 PF00675 0.493
CLV_NRD_NRD_1 693 695 PF00675 0.590
CLV_NRD_NRD_1 808 810 PF00675 0.658
CLV_PCSK_FUR_1 113 117 PF00082 0.646
CLV_PCSK_KEX2_1 115 117 PF00082 0.659
CLV_PCSK_KEX2_1 342 344 PF00082 0.493
CLV_PCSK_KEX2_1 693 695 PF00082 0.590
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P6Y6 Leptomonas seymouri 44% 88%
A4HYY4 Leishmania infantum 99% 100%
E9AIJ8 Leishmania braziliensis 73% 100%
E9AUT0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QCQ3 Leishmania major 92% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS