LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7WW27_LEIDO
TriTrypDb:
LdBPK_201090.1 , LdCL_200015600 , LDHU3_20.1350
Length:
275

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WW27
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WW27

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 160 162 PF00675 0.649
CLV_NRD_NRD_1 167 169 PF00675 0.550
CLV_NRD_NRD_1 181 183 PF00675 0.568
CLV_NRD_NRD_1 207 209 PF00675 0.630
CLV_NRD_NRD_1 233 235 PF00675 0.621
CLV_NRD_NRD_1 272 274 PF00675 0.633
CLV_NRD_NRD_1 83 85 PF00675 0.573
CLV_NRD_NRD_1 97 99 PF00675 0.473
CLV_PCSK_KEX2_1 158 160 PF00082 0.645
CLV_PCSK_KEX2_1 167 169 PF00082 0.533
CLV_PCSK_KEX2_1 183 185 PF00082 0.565
CLV_PCSK_KEX2_1 207 209 PF00082 0.796
CLV_PCSK_KEX2_1 233 235 PF00082 0.618
CLV_PCSK_KEX2_1 262 264 PF00082 0.716
CLV_PCSK_KEX2_1 272 274 PF00082 0.613
CLV_PCSK_KEX2_1 83 85 PF00082 0.536
CLV_PCSK_KEX2_1 97 99 PF00082 0.509
CLV_PCSK_PC1ET2_1 158 160 PF00082 0.645
CLV_PCSK_PC1ET2_1 183 185 PF00082 0.590
CLV_PCSK_PC1ET2_1 262 264 PF00082 0.612
CLV_PCSK_PC1ET2_1 272 274 PF00082 0.583
CLV_PCSK_PC1ET2_1 83 85 PF00082 0.482
CLV_PCSK_PC7_1 79 85 PF00082 0.471
CLV_PCSK_SKI1_1 155 159 PF00082 0.651
CLV_PCSK_SKI1_1 161 165 PF00082 0.575
CLV_PCSK_SKI1_1 84 88 PF00082 0.544
DEG_Nend_UBRbox_3 1 3 PF02207 0.608
DOC_CKS1_1 47 52 PF01111 0.559
DOC_MAPK_gen_1 207 216 PF00069 0.591
DOC_MAPK_gen_1 30 39 PF00069 0.550
DOC_MAPK_gen_1 57 66 PF00069 0.432
DOC_MAPK_MEF2A_6 207 216 PF00069 0.591
DOC_PP2B_LxvP_1 122 125 PF13499 0.589
DOC_PP4_FxxP_1 33 36 PF00568 0.574
DOC_USP7_MATH_1 106 110 PF00917 0.616
DOC_USP7_MATH_1 125 129 PF00917 0.705
DOC_USP7_MATH_1 138 142 PF00917 0.567
DOC_USP7_MATH_1 174 178 PF00917 0.612
DOC_USP7_MATH_1 192 196 PF00917 0.523
DOC_USP7_MATH_1 225 229 PF00917 0.600
DOC_USP7_MATH_1 28 32 PF00917 0.550
DOC_USP7_UBL2_3 144 148 PF12436 0.676
DOC_USP7_UBL2_3 151 155 PF12436 0.491
DOC_USP7_UBL2_3 158 162 PF12436 0.612
DOC_USP7_UBL2_3 249 253 PF12436 0.554
DOC_USP7_UBL2_3 53 57 PF12436 0.514
DOC_USP7_UBL2_3 83 87 PF12436 0.491
DOC_WW_Pin1_4 117 122 PF00397 0.571
DOC_WW_Pin1_4 15 20 PF00397 0.574
DOC_WW_Pin1_4 175 180 PF00397 0.698
DOC_WW_Pin1_4 46 51 PF00397 0.573
LIG_14-3-3_CanoR_1 161 169 PF00244 0.608
LIG_14-3-3_CanoR_1 237 243 PF00244 0.699
LIG_Actin_WH2_2 150 166 PF00022 0.585
LIG_BIR_III_2 25 29 PF00653 0.551
LIG_BRCT_BRCA1_1 119 123 PF00533 0.546
LIG_FHA_1 124 130 PF00498 0.595
LIG_FHA_1 88 94 PF00498 0.606
LIG_FHA_2 47 53 PF00498 0.557
LIG_LIR_Apic_2 31 36 PF02991 0.588
LIG_RPA_C_Fungi 74 86 PF08784 0.467
LIG_SH2_STAT5 21 24 PF00017 0.571
LIG_SH3_1 130 136 PF00018 0.645
LIG_SH3_3 118 124 PF00018 0.592
LIG_SH3_3 130 136 PF00018 0.576
LIG_SH3_3 198 204 PF00018 0.606
LIG_SH3_3 206 212 PF00018 0.556
LIG_SH3_3 240 246 PF00018 0.611
LIG_SUMO_SIM_par_1 41 49 PF11976 0.635
LIG_SUMO_SIM_par_1 62 69 PF11976 0.418
LIG_TRAF2_1 49 52 PF00917 0.559
LIG_TRAF2_1 6 9 PF00917 0.601
LIG_TRAF2_1 65 68 PF00917 0.359
MOD_CDK_SPxxK_3 175 182 PF00069 0.587
MOD_CDK_SPxxK_3 46 53 PF00069 0.561
MOD_CK1_1 146 152 PF00069 0.640
MOD_CK1_1 178 184 PF00069 0.684
MOD_CK1_1 248 254 PF00069 0.511
MOD_CK2_1 38 44 PF00069 0.651
MOD_CK2_1 46 52 PF00069 0.526
MOD_Cter_Amidation 159 162 PF01082 0.610
MOD_Cter_Amidation 231 234 PF01082 0.629
MOD_Cter_Amidation 270 273 PF01082 0.608
MOD_GSK3_1 17 24 PF00069 0.517
MOD_GSK3_1 174 181 PF00069 0.646
MOD_GSK3_1 9 16 PF00069 0.567
MOD_NEK2_1 163 168 PF00069 0.591
MOD_NEK2_1 247 252 PF00069 0.531
MOD_NEK2_2 125 130 PF00069 0.597
MOD_PKA_1 207 213 PF00069 0.588
MOD_PKA_2 185 191 PF00069 0.626
MOD_PKA_2 207 213 PF00069 0.588
MOD_Plk_4 17 23 PF00069 0.595
MOD_Plk_4 238 244 PF00069 0.616
MOD_ProDKin_1 117 123 PF00069 0.570
MOD_ProDKin_1 15 21 PF00069 0.572
MOD_ProDKin_1 175 181 PF00069 0.696
MOD_ProDKin_1 46 52 PF00069 0.569
MOD_SUMO_for_1 147 150 PF00179 0.644
TRG_ER_diArg_1 167 170 PF00400 0.615
TRG_ER_diArg_1 207 209 PF00400 0.649
TRG_ER_diArg_1 221 224 PF00400 0.515
TRG_ER_diArg_1 29 32 PF00400 0.548
TRG_ER_diArg_1 97 99 PF00400 0.626
TRG_NLS_Bipartite_1 167 187 PF00514 0.585
TRG_NLS_MonoExtC_3 157 162 PF00514 0.650
TRG_NLS_MonoExtC_3 181 186 PF00514 0.589
TRG_NLS_MonoExtC_3 82 87 PF00514 0.486
TRG_NLS_MonoExtN_4 155 162 PF00514 0.650
TRG_NLS_MonoExtN_4 179 186 PF00514 0.588
TRG_NLS_MonoExtN_4 83 88 PF00514 0.498
TRG_Pf-PMV_PEXEL_1 170 175 PF00026 0.636

Homologs

Protein Taxonomy Sequence identity Coverage
A4HYU9 Leishmania infantum 99% 100%
E9AIF6 Leishmania braziliensis 53% 99%
E9AUP6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
Q4QCT9 Leishmania major 79% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS