Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WVY4_LEIDO

TriTrypDb:

LdBPK_201000.1 , LdCL_200014700 , LDHU3_20.1230

Length:

508

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WVY4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVY4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	188	192	PF00656	0.716
CLV_NRD_NRD_1	24	26	PF00675	0.639
CLV_NRD_NRD_1	335	337	PF00675	0.721
CLV_NRD_NRD_1	348	350	PF00675	0.474
CLV_NRD_NRD_1	418	420	PF00675	0.766
CLV_NRD_NRD_1	46	48	PF00675	0.722
CLV_NRD_NRD_1	65	67	PF00675	0.463
CLV_PCSK_KEX2_1	140	142	PF00082	0.558
CLV_PCSK_KEX2_1	24	26	PF00082	0.639
CLV_PCSK_KEX2_1	294	296	PF00082	0.743
CLV_PCSK_KEX2_1	303	305	PF00082	0.569
CLV_PCSK_KEX2_1	335	337	PF00082	0.640
CLV_PCSK_KEX2_1	348	350	PF00082	0.645
CLV_PCSK_KEX2_1	46	48	PF00082	0.722
CLV_PCSK_KEX2_1	65	67	PF00082	0.463
CLV_PCSK_PC1ET2_1	140	142	PF00082	0.558
CLV_PCSK_PC1ET2_1	294	296	PF00082	0.743
CLV_PCSK_PC1ET2_1	303	305	PF00082	0.569
CLV_PCSK_PC7_1	331	337	PF00082	0.709
CLV_PCSK_SKI1_1	24	28	PF00082	0.768
CLV_PCSK_SKI1_1	303	307	PF00082	0.581
CLV_PCSK_SKI1_1	331	335	PF00082	0.695
DEG_APCC_DBOX_1	330	338	PF00400	0.707
DEG_APCC_DBOX_1	441	449	PF00400	0.645
DEG_Nend_UBRbox_1	1	4	PF02207	0.693
DEG_SPOP_SBC_1	277	281	PF00917	0.618
DEG_SPOP_SBC_1	469	473	PF00917	0.741
DEG_SPOP_SBC_1	85	89	PF00917	0.626
DOC_ANK_TNKS_1	140	147	PF00023	0.577
DOC_MAPK_gen_1	303	311	PF00069	0.525
DOC_MAPK_gen_1	439	448	PF00069	0.609
DOC_MAPK_MEF2A_6	304	313	PF00069	0.520
DOC_MAPK_MEF2A_6	364	372	PF00069	0.667
DOC_MAPK_MEF2A_6	442	450	PF00069	0.611
DOC_PP2B_LxvP_1	274	277	PF13499	0.744
DOC_PP2B_LxvP_1	288	291	PF13499	0.717
DOC_PP4_FxxP_1	142	145	PF00568	0.591
DOC_USP7_MATH_1	179	183	PF00917	0.560
DOC_USP7_MATH_1	278	282	PF00917	0.672
DOC_USP7_MATH_1	467	471	PF00917	0.775
DOC_USP7_MATH_1	53	57	PF00917	0.706
DOC_USP7_MATH_1	79	83	PF00917	0.698
DOC_USP7_MATH_1	84	88	PF00917	0.631
DOC_WW_Pin1_4	19	24	PF00397	0.648
DOC_WW_Pin1_4	397	402	PF00397	0.597
DOC_WW_Pin1_4	412	417	PF00397	0.536
DOC_WW_Pin1_4	465	470	PF00397	0.698
LIG_14-3-3_CanoR_1	304	309	PF00244	0.517
LIG_14-3-3_CanoR_1	348	352	PF00244	0.503
LIG_14-3-3_CanoR_1	419	427	PF00244	0.832
LIG_14-3-3_CanoR_1	442	446	PF00244	0.650
LIG_14-3-3_CterR_2	505	508	PF00244	0.629
LIG_Actin_WH2_2	322	337	PF00022	0.706
LIG_APCC_ABBA_1	252	257	PF00400	0.533
LIG_BRCT_BRCA1_1	119	123	PF00533	0.537
LIG_BRCT_BRCA1_1	2	6	PF00533	0.582
LIG_BRCT_BRCA1_1	460	464	PF00533	0.769
LIG_CaM_IQ_9	370	385	PF13499	0.651
LIG_DLG_GKlike_1	164	172	PF00625	0.669
LIG_FHA_1	122	128	PF00498	0.670
LIG_FHA_1	219	225	PF00498	0.534
LIG_FHA_1	304	310	PF00498	0.556
LIG_FHA_1	35	41	PF00498	0.546
LIG_FHA_1	352	358	PF00498	0.531
LIG_FHA_1	442	448	PF00498	0.622
LIG_FHA_1	476	482	PF00498	0.637
LIG_FHA_1	87	93	PF00498	0.708
LIG_FHA_2	198	204	PF00498	0.760
LIG_FHA_2	67	73	PF00498	0.613
LIG_LIR_Apic_2	56	62	PF02991	0.646
LIG_LIR_Gen_1	120	131	PF02991	0.494
LIG_LIR_Gen_1	307	316	PF02991	0.591
LIG_LIR_Gen_1	365	373	PF02991	0.612
LIG_LIR_Gen_1	45	55	PF02991	0.558
LIG_LIR_Nem_3	120	126	PF02991	0.517
LIG_LIR_Nem_3	3	9	PF02991	0.571
LIG_LIR_Nem_3	307	313	PF02991	0.594
LIG_LIR_Nem_3	365	369	PF02991	0.530
LIG_LIR_Nem_3	45	51	PF02991	0.548
LIG_RPA_C_Fungi	42	54	PF08784	0.675
LIG_SH2_CRK	493	497	PF00017	0.588
LIG_SH2_CRK	59	63	PF00017	0.654
LIG_SH2_NCK_1	155	159	PF00017	0.695
LIG_SH2_NCK_1	59	63	PF00017	0.698
LIG_SH2_PTP2	310	313	PF00017	0.700
LIG_SH2_SRC	155	158	PF00017	0.687
LIG_SH2_STAP1	353	357	PF00017	0.650
LIG_SH2_STAT5	130	133	PF00017	0.525
LIG_SH2_STAT5	174	177	PF00017	0.579
LIG_SH2_STAT5	262	265	PF00017	0.560
LIG_SH2_STAT5	310	313	PF00017	0.603
LIG_SH2_STAT5	353	356	PF00017	0.496
LIG_SH2_STAT5	361	364	PF00017	0.508
LIG_SH2_STAT5	455	458	PF00017	0.546
LIG_SH3_3	1	7	PF00018	0.759
LIG_SH3_3	142	148	PF00018	0.572
LIG_SH3_3	354	360	PF00018	0.650
LIG_SH3_3	398	404	PF00018	0.597
LIG_SUMO_SIM_anti_2	221	226	PF11976	0.536
LIG_SUMO_SIM_anti_2	444	449	PF11976	0.617
LIG_SUMO_SIM_par_1	265	271	PF11976	0.665
LIG_SUMO_SIM_par_1	87	93	PF11976	0.705
LIG_TYR_ITIM	153	158	PF00017	0.693
LIG_TYR_ITIM	308	313	PF00017	0.692
LIG_WRC_WIRS_1	363	368	PF05994	0.671
MOD_CDC14_SPxK_1	22	25	PF00782	0.625
MOD_CDK_SPK_2	19	24	PF00069	0.742
MOD_CDK_SPK_2	397	402	PF00069	0.597
MOD_CDK_SPK_2	412	417	PF00069	0.536
MOD_CDK_SPxK_1	19	25	PF00069	0.617
MOD_CDK_SPxxK_3	412	419	PF00069	0.645
MOD_CK1_1	116	122	PF00069	0.738
MOD_CK1_1	182	188	PF00069	0.727
MOD_CK1_1	315	321	PF00069	0.711
MOD_CK1_1	32	38	PF00069	0.708
MOD_CK1_1	405	411	PF00069	0.661
MOD_CK1_1	412	418	PF00069	0.666
MOD_CK1_1	458	464	PF00069	0.657
MOD_CK1_1	465	471	PF00069	0.693
MOD_CK1_1	93	99	PF00069	0.649
MOD_CK2_1	119	125	PF00069	0.706
MOD_CK2_1	277	283	PF00069	0.595
MOD_CK2_1	66	72	PF00069	0.633
MOD_GlcNHglycan	148	151	PF01048	0.699
MOD_GlcNHglycan	159	162	PF01048	0.498
MOD_GlcNHglycan	185	188	PF01048	0.663
MOD_GlcNHglycan	208	211	PF01048	0.667
MOD_GlcNHglycan	27	30	PF01048	0.684
MOD_GlcNHglycan	280	283	PF01048	0.632
MOD_GlcNHglycan	314	317	PF01048	0.695
MOD_GlcNHglycan	408	411	PF01048	0.718
MOD_GlcNHglycan	428	431	PF01048	0.491
MOD_GlcNHglycan	464	467	PF01048	0.756
MOD_GlcNHglycan	496	499	PF01048	0.682
MOD_GlcNHglycan	55	58	PF01048	0.637
MOD_GlcNHglycan	82	85	PF01048	0.657
MOD_GlcNHglycan	92	95	PF01048	0.627
MOD_GSK3_1	113	120	PF00069	0.642
MOD_GSK3_1	15	22	PF00069	0.697
MOD_GSK3_1	164	171	PF00069	0.672
MOD_GSK3_1	179	186	PF00069	0.469
MOD_GSK3_1	214	221	PF00069	0.598
MOD_GSK3_1	25	32	PF00069	0.631
MOD_GSK3_1	347	354	PF00069	0.643
MOD_GSK3_1	402	409	PF00069	0.657
MOD_GSK3_1	458	465	PF00069	0.674
MOD_GSK3_1	467	474	PF00069	0.732
MOD_GSK3_1	80	87	PF00069	0.707
MOD_LATS_1	162	168	PF00433	0.672
MOD_N-GLC_1	318	323	PF02516	0.722
MOD_NEK2_1	168	173	PF00069	0.572
MOD_NEK2_1	180	185	PF00069	0.622
MOD_NEK2_1	204	209	PF00069	0.721
MOD_NEK2_1	218	223	PF00069	0.435
MOD_NEK2_1	347	352	PF00069	0.557
MOD_NEK2_1	42	47	PF00069	0.619
MOD_NEK2_1	8	13	PF00069	0.728
MOD_NEK2_1	90	95	PF00069	0.695
MOD_NEK2_2	256	261	PF00069	0.667
MOD_PIKK_1	110	116	PF00454	0.749
MOD_PIKK_1	228	234	PF00454	0.507
MOD_PIKK_1	471	477	PF00454	0.745
MOD_PK_1	304	310	PF00069	0.520
MOD_PK_1	402	408	PF00069	0.619
MOD_PKA_1	303	309	PF00069	0.522
MOD_PKA_1	494	500	PF00069	0.626
MOD_PKA_2	29	35	PF00069	0.627
MOD_PKA_2	303	309	PF00069	0.522
MOD_PKA_2	347	353	PF00069	0.631
MOD_PKA_2	441	447	PF00069	0.646
MOD_Plk_1	214	220	PF00069	0.553
MOD_Plk_4	304	310	PF00069	0.695
MOD_Plk_4	441	447	PF00069	0.724
MOD_Plk_4	93	99	PF00069	0.578
MOD_ProDKin_1	19	25	PF00069	0.649
MOD_ProDKin_1	397	403	PF00069	0.597
MOD_ProDKin_1	412	418	PF00069	0.530
MOD_ProDKin_1	465	471	PF00069	0.697
MOD_SUMO_for_1	293	296	PF00179	0.745
TRG_ENDOCYTIC_2	139	142	PF00928	0.679
TRG_ENDOCYTIC_2	155	158	PF00928	0.395
TRG_ENDOCYTIC_2	310	313	PF00928	0.603
TRG_ENDOCYTIC_2	493	496	PF00928	0.593
TRG_ER_diArg_1	23	25	PF00400	0.633
TRG_ER_diArg_1	334	336	PF00400	0.720
TRG_ER_diArg_1	347	349	PF00400	0.472
TRG_ER_diArg_1	416	419	PF00400	0.788
TRG_ER_diArg_1	46	48	PF00400	0.722
TRG_ER_diArg_1	504	507	PF00400	0.615
TRG_ER_diArg_1	65	67	PF00400	0.463

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P496	Leptomonas seymouri	42%	91%
E9AGU1	Leishmania infantum	100%	100%
E9AUN7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4QCU7	Leishmania major	85%	100%