SSU_ribosomal_protein_mitochondrial_putative/Gene DB:LmjF.20.0510

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SSU ribosomal protein, mitochondrial, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WVW4_LEIDO

TriTrypDb:

LdBPK_200580.1 , LdCL_200010500 , LDHU3_20.0700

Length:

429

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	5
GO:0032991	protein-containing complex	1	6
GO:0043226	organelle	2	5
GO:0043228	non-membrane-bounded organelle	3	5
GO:0043229	intracellular organelle	3	5
GO:0043232	intracellular non-membrane-bounded organelle	4	5
GO:0110165	cellular anatomical entity	1	5
GO:1990904	ribonucleoprotein complex	2	6
GO:0000314	organellar small ribosomal subunit	5	1
GO:0005763	mitochondrial small ribosomal subunit	3	1
GO:0015935	small ribosomal subunit	4	1
GO:0044391	ribosomal subunit	3	1
GO:0098798	mitochondrial protein-containing complex	2	1

Expansion

Sequence features

A0A3S7WVW4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVW4

PDB structure(s): 7ane_i

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	6
GO:0006518	peptide metabolic process	4	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0008152	metabolic process	1	6
GO:0009058	biosynthetic process	2	6
GO:0009059	macromolecule biosynthetic process	4	6
GO:0009987	cellular process	1	6
GO:0019538	protein metabolic process	3	6
GO:0034641	cellular nitrogen compound metabolic process	3	6
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	6
GO:0043043	peptide biosynthetic process	5	6
GO:0043170	macromolecule metabolic process	3	6
GO:0043603	amide metabolic process	3	6
GO:0043604	amide biosynthetic process	4	6
GO:0044237	cellular metabolic process	2	6
GO:0044238	primary metabolic process	2	6
GO:0044249	cellular biosynthetic process	3	6
GO:0044260	obsolete cellular macromolecule metabolic process	3	6
GO:0044271	cellular nitrogen compound biosynthetic process	4	6
GO:0071704	organic substance metabolic process	2	6
GO:1901564	organonitrogen compound metabolic process	3	6
GO:1901566	organonitrogen compound biosynthetic process	4	6
GO:1901576	organic substance biosynthetic process	3	6

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	6
GO:0005198	structural molecule activity	1	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	40	44	PF00656	0.531
CLV_NRD_NRD_1	13	15	PF00675	0.572
CLV_NRD_NRD_1	163	165	PF00675	0.397
CLV_NRD_NRD_1	256	258	PF00675	0.384
CLV_NRD_NRD_1	264	266	PF00675	0.324
CLV_NRD_NRD_1	387	389	PF00675	0.397
CLV_NRD_NRD_1	410	412	PF00675	0.422
CLV_NRD_NRD_1	55	57	PF00675	0.523
CLV_NRD_NRD_1	79	81	PF00675	0.491
CLV_PCSK_KEX2_1	163	165	PF00082	0.388
CLV_PCSK_KEX2_1	227	229	PF00082	0.353
CLV_PCSK_KEX2_1	264	266	PF00082	0.390
CLV_PCSK_KEX2_1	272	274	PF00082	0.405
CLV_PCSK_KEX2_1	424	426	PF00082	0.450
CLV_PCSK_KEX2_1	55	57	PF00082	0.527
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.353
CLV_PCSK_PC1ET2_1	272	274	PF00082	0.530
CLV_PCSK_PC1ET2_1	424	426	PF00082	0.436
CLV_PCSK_PC7_1	420	426	PF00082	0.418
CLV_PCSK_SKI1_1	186	190	PF00082	0.390
CLV_PCSK_SKI1_1	227	231	PF00082	0.376
CLV_PCSK_SKI1_1	249	253	PF00082	0.389
CLV_PCSK_SKI1_1	366	370	PF00082	0.380
CLV_PCSK_SKI1_1	411	415	PF00082	0.418
CLV_PCSK_SKI1_1	94	98	PF00082	0.395
DEG_MDM2_SWIB_1	271	278	PF02201	0.342
DEG_Nend_Nbox_1	1	3	PF02207	0.545
DOC_CKS1_1	85	90	PF01111	0.454
DOC_CYCLIN_RxL_1	408	416	PF00134	0.413
DOC_MAPK_gen_1	227	234	PF00069	0.459
DOC_MAPK_gen_1	264	271	PF00069	0.401
DOC_MAPK_gen_1	385	395	PF00069	0.447
DOC_MAPK_MEF2A_6	227	234	PF00069	0.459
DOC_MAPK_MEF2A_6	388	397	PF00069	0.453
DOC_PP1_RVXF_1	265	272	PF00149	0.375
DOC_PP2B_LxvP_1	287	290	PF13499	0.463
DOC_PP4_FxxP_1	171	174	PF00568	0.371
DOC_SPAK_OSR1_1	170	174	PF12202	0.372
DOC_USP7_UBL2_3	227	231	PF12436	0.354
DOC_USP7_UBL2_3	268	272	PF12436	0.379
DOC_USP7_UBL2_3	396	400	PF12436	0.460
DOC_WW_Pin1_4	105	110	PF00397	0.393
DOC_WW_Pin1_4	217	222	PF00397	0.379
DOC_WW_Pin1_4	84	89	PF00397	0.441
LIG_14-3-3_CanoR_1	170	174	PF00244	0.494
LIG_14-3-3_CanoR_1	332	341	PF00244	0.385
LIG_14-3-3_CanoR_1	420	428	PF00244	0.526
LIG_14-3-3_CanoR_1	55	61	PF00244	0.513
LIG_BRCT_BRCA1_1	390	394	PF00533	0.410
LIG_BRCT_BRCA1_2	390	396	PF00533	0.410
LIG_CtBP_PxDLS_1	289	293	PF00389	0.475
LIG_FHA_1	173	179	PF00498	0.387
LIG_FHA_1	3	9	PF00498	0.628
LIG_FHA_1	344	350	PF00498	0.426
LIG_FHA_2	193	199	PF00498	0.500
LIG_LIR_Apic_2	168	174	PF02991	0.372
LIG_LIR_Apic_2	344	348	PF02991	0.414
LIG_LIR_Gen_1	23	31	PF02991	0.683
LIG_LIR_Gen_1	391	399	PF02991	0.433
LIG_LIR_Nem_3	23	28	PF02991	0.692
LIG_LIR_Nem_3	270	274	PF02991	0.355
LIG_LIR_Nem_3	299	303	PF02991	0.376
LIG_LIR_Nem_3	408	413	PF02991	0.404
LIG_Pex14_1	156	160	PF04695	0.356
LIG_Pex14_2	271	275	PF04695	0.358
LIG_Pex14_2	386	390	PF04695	0.397
LIG_SH2_CRK	345	349	PF00017	0.405
LIG_SH2_CRK	410	414	PF00017	0.405
LIG_SH2_SRC	211	214	PF00017	0.389
LIG_SH2_STAP1	167	171	PF00017	0.376
LIG_SH2_STAP1	303	307	PF00017	0.392
LIG_SH2_STAP1	364	368	PF00017	0.374
LIG_SH2_STAP1	4	8	PF00017	0.672
LIG_SH2_STAT5	345	348	PF00017	0.412
LIG_SH2_STAT5	4	7	PF00017	0.552
LIG_SH3_1	80	86	PF00018	0.394
LIG_SH3_3	119	125	PF00018	0.425
LIG_SH3_3	283	289	PF00018	0.469
LIG_SH3_3	315	321	PF00018	0.409
LIG_SH3_3	401	407	PF00018	0.396
LIG_SH3_3	80	86	PF00018	0.394
LIG_TRAF2_1	195	198	PF00917	0.398
LIG_TRAF2_1	348	351	PF00917	0.488
LIG_TRAF2_1	64	67	PF00917	0.490
LIG_TYR_ITIM	362	367	PF00017	0.400
LIG_UBA3_1	103	112	PF00899	0.517
LIG_UBA3_1	193	199	PF00899	0.412
LIG_UBA3_1	393	400	PF00899	0.462
MOD_CDK_SPxxK_3	105	112	PF00069	0.385
MOD_CK1_1	172	178	PF00069	0.464
MOD_CK1_1	192	198	PF00069	0.338
MOD_CK1_1	23	29	PF00069	0.700
MOD_CK1_1	3	9	PF00069	0.639
MOD_CK2_1	192	198	PF00069	0.394
MOD_CK2_1	330	336	PF00069	0.413
MOD_CMANNOS	76	79	PF00535	0.405
MOD_GlcNHglycan	390	393	PF01048	0.410
MOD_GlcNHglycan	400	403	PF01048	0.386
MOD_GlcNHglycan	5	8	PF01048	0.539
MOD_GlcNHglycan	58	61	PF01048	0.563
MOD_LATS_1	54	60	PF00433	0.646
MOD_N-GLC_1	105	110	PF02516	0.433
MOD_N-GLC_1	181	186	PF02516	0.488
MOD_N-GLC_1	23	28	PF02516	0.686
MOD_N-GLC_1	259	264	PF02516	0.480
MOD_N-GLC_2	325	327	PF02516	0.396
MOD_NEK2_1	138	143	PF00069	0.501
MOD_NEK2_1	189	194	PF00069	0.460
MOD_NEK2_1	2	7	PF00069	0.541
MOD_NEK2_1	216	221	PF00069	0.376
MOD_NEK2_1	259	264	PF00069	0.509
MOD_NEK2_1	309	314	PF00069	0.369
MOD_NEK2_1	341	346	PF00069	0.403
MOD_NEK2_1	413	418	PF00069	0.413
MOD_NEK2_2	181	186	PF00069	0.440
MOD_PIKK_1	310	316	PF00454	0.512
MOD_PIKK_1	413	419	PF00454	0.527
MOD_PIKK_1	89	95	PF00454	0.481
MOD_PKA_1	388	394	PF00069	0.407
MOD_PKA_2	169	175	PF00069	0.415
MOD_PKA_2	20	26	PF00069	0.699
MOD_PKA_2	419	425	PF00069	0.526
MOD_PKA_2	54	60	PF00069	0.514
MOD_Plk_1	181	187	PF00069	0.489
MOD_Plk_1	259	265	PF00069	0.487
MOD_Plk_4	189	195	PF00069	0.436
MOD_Plk_4	247	253	PF00069	0.445
MOD_Plk_4	296	302	PF00069	0.451
MOD_ProDKin_1	105	111	PF00069	0.385
MOD_ProDKin_1	217	223	PF00069	0.374
MOD_ProDKin_1	84	90	PF00069	0.446
MOD_SUMO_for_1	37	40	PF00179	0.618
MOD_SUMO_for_1	370	373	PF00179	0.390
MOD_SUMO_rev_2	351	357	PF00179	0.418
TRG_DiLeu_BaEn_2	381	387	PF01217	0.401
TRG_DiLeu_BaLyEn_6	134	139	PF01217	0.478
TRG_ENDOCYTIC_2	274	277	PF00928	0.361
TRG_ENDOCYTIC_2	364	367	PF00928	0.385
TRG_ENDOCYTIC_2	410	413	PF00928	0.413
TRG_ER_diArg_1	263	265	PF00400	0.453
TRG_ER_diArg_1	50	53	PF00400	0.524
TRG_Pf-PMV_PEXEL_1	347	351	PF00026	0.413
TRG_Pf-PMV_PEXEL_1	355	359	PF00026	0.397

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDF7	Leptomonas seymouri	90%	100%
A0A0S4J4D7	Bodo saltans	63%	100%
A0A1X0NWF9	Trypanosomatidae	81%	100%
A0A422NCH8	Trypanosoma rangeli	81%	100%
A4HYR0	Leishmania infantum	100%	100%
C9ZI69	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	80%	100%
E9AIA8	Leishmania braziliensis	94%	100%
E9AUJ5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4QCY9	Leishmania major	99%	100%