DUF4198 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

conserved protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WVT6_LEIDO

TriTrypDb:

LdBPK_200600.1 , LdCL_200010700 , LDHU3_20.0720

Length:

144


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

A0A3S7WVT6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVT6

PDB structure(s): 7aih_J , 7am2_J , 7ane_J


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	74	78	PF00656	0.484
CLV_PCSK_SKI1_1	10	14	PF00082	0.492
DOC_PP2B_LxvP_1	102	105	PF13499	0.477
DOC_USP7_MATH_1	118	122	PF00917	0.586
DOC_USP7_UBL2_3	40	44	PF12436	0.645
DOC_USP7_UBL2_3	86	90	PF12436	0.491
DOC_WW_Pin1_4	53	58	PF00397	0.600
LIG_CSL_BTD_1	102	105	PF09270	0.477
LIG_FHA_2	72	78	PF00498	0.496
LIG_LIR_Nem_3	121	125	PF02991	0.497
LIG_REV1ctd_RIR_1	10	20	PF16727	0.470
LIG_SH2_STAT5	125	128	PF00017	0.528
LIG_SH2_STAT5	3	6	PF00017	0.508
MOD_CK1_1	56	62	PF00069	0.588
MOD_CK2_1	90	96	PF00069	0.516
MOD_GlcNHglycan	116	119	PF01048	0.609
MOD_GSK3_1	1	8	PF00069	0.497
MOD_GSK3_1	114	121	PF00069	0.518
MOD_GSK3_1	77	84	PF00069	0.503
MOD_NEK2_1	12	17	PF00069	0.579
MOD_NEK2_1	71	76	PF00069	0.468
MOD_PKA_1	39	45	PF00069	0.545
MOD_Plk_1	80	86	PF00069	0.516
MOD_Plk_2-3	77	83	PF00069	0.500
MOD_Plk_4	71	77	PF00069	0.474
MOD_ProDKin_1	53	59	PF00069	0.600
MOD_SUMO_for_1	111	114	PF00179	0.536
TRG_DiLeu_BaEn_3	96	102	PF01217	0.515
TRG_DiLeu_BaLyEn_6	67	72	PF01217	0.481
TRG_ER_diArg_1	140	143	PF00400	0.538
TRG_Pf-PMV_PEXEL_1	31	36	PF00026	0.526


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7H3	Leptomonas seymouri	94%	100%
A0A0S4J6A6	Bodo saltans	75%	100%
A0A1X0NX43	Trypanosomatidae	88%	100%
A0A422NCH2	Trypanosoma rangeli	89%	100%
A4HYQ8	Leishmania infantum	100%	100%
C9ZI70	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	85%	100%
E9AIB0	Leishmania braziliensis	97%	100%
E9AUJ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4QCY7	Leishmania major	97%	100%