LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7WVS2_LEIDO
TriTrypDb:
LdBPK_191610.1 , LdCL_190021900 , LDHU3_19.1950
Length:
373

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WVS2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVS2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 186 190 PF00656 0.573
CLV_C14_Caspase3-7 247 251 PF00656 0.662
CLV_C14_Caspase3-7 260 264 PF00656 0.555
CLV_NRD_NRD_1 111 113 PF00675 0.502
CLV_NRD_NRD_1 214 216 PF00675 0.683
CLV_NRD_NRD_1 56 58 PF00675 0.661
CLV_NRD_NRD_1 65 67 PF00675 0.479
CLV_PCSK_KEX2_1 111 113 PF00082 0.502
CLV_PCSK_KEX2_1 214 216 PF00082 0.683
CLV_PCSK_KEX2_1 56 58 PF00082 0.661
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IB12 Leptomonas seymouri 34% 95%
A4HAA7 Leishmania braziliensis 74% 100%
A4HYI7 Leishmania infantum 99% 100%
E9ASB1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QD51 Leishmania major 92% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS