Ice-nucleation protein octamer repeat protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7WVR7_LEIDO

TriTrypDb:

LdCL_190023300

Length:

1000

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WVR7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVR7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	206	210	PF00656	0.497
CLV_C14_Caspase3-7	247	251	PF00656	0.445
CLV_C14_Caspase3-7	328	332	PF00656	0.461
CLV_C14_Caspase3-7	382	386	PF00656	0.427
CLV_C14_Caspase3-7	449	453	PF00656	0.476
CLV_C14_Caspase3-7	571	575	PF00656	0.375
CLV_C14_Caspase3-7	679	683	PF00656	0.392
CLV_C14_Caspase3-7	773	777	PF00656	0.465
CLV_NRD_NRD_1	115	117	PF00675	0.572
CLV_NRD_NRD_1	142	144	PF00675	0.575
CLV_NRD_NRD_1	170	172	PF00675	0.562
CLV_NRD_NRD_1	42	44	PF00675	0.637
CLV_NRD_NRD_1	67	69	PF00675	0.572
CLV_NRD_NRD_1	84	86	PF00675	0.707
CLV_PCSK_FUR_1	140	144	PF00082	0.577
CLV_PCSK_KEX2_1	115	117	PF00082	0.572
CLV_PCSK_KEX2_1	142	144	PF00082	0.575
CLV_PCSK_KEX2_1	169	171	PF00082	0.556
CLV_PCSK_KEX2_1	42	44	PF00082	0.536
CLV_PCSK_KEX2_1	66	68	PF00082	0.584
CLV_PCSK_KEX2_1	84	86	PF00082	0.546
CLV_PCSK_PC7_1	165	171	PF00082	0.546
CLV_PCSK_PC7_1	62	68	PF00082	0.579
CLV_PCSK_SKI1_1	42	46	PF00082	0.538
DEG_Nend_UBRbox_1	1	4	PF02207	0.536
DOC_CKS1_1	896	901	PF01111	0.575
DOC_CKS1_1	923	928	PF01111	0.586
DOC_CKS1_1	950	955	PF01111	0.594
DOC_CKS1_1	977	982	PF01111	0.587
DOC_CYCLIN_yCln2_LP_2	896	902	PF00134	0.572
DOC_CYCLIN_yCln2_LP_2	923	929	PF00134	0.584
DOC_CYCLIN_yCln2_LP_2	977	983	PF00134	0.586
DOC_MAPK_DCC_7	115	124	PF00069	0.565
DOC_PP1_RVXF_1	118	125	PF00149	0.562
DOC_USP7_MATH_1	102	106	PF00917	0.485
DOC_USP7_MATH_1	174	178	PF00917	0.546
DOC_USP7_MATH_1	87	91	PF00917	0.534
DOC_USP7_MATH_1	93	97	PF00917	0.511
DOC_USP7_MATH_1	955	959	PF00917	0.598
DOC_WW_Pin1_4	115	120	PF00397	0.562
DOC_WW_Pin1_4	126	131	PF00397	0.514
DOC_WW_Pin1_4	149	154	PF00397	0.559
DOC_WW_Pin1_4	895	900	PF00397	0.576
DOC_WW_Pin1_4	922	927	PF00397	0.583
DOC_WW_Pin1_4	949	954	PF00397	0.596
DOC_WW_Pin1_4	976	981	PF00397	0.588
LIG_14-3-3_CanoR_1	108	114	PF00244	0.578
LIG_14-3-3_CanoR_1	115	119	PF00244	0.543
LIG_14-3-3_CanoR_1	887	896	PF00244	0.582
LIG_14-3-3_CanoR_1	914	923	PF00244	0.581
LIG_14-3-3_CanoR_1	941	950	PF00244	0.598
LIG_14-3-3_CanoR_1	968	977	PF00244	0.592
LIG_BIR_III_4	37	41	PF00653	0.516
LIG_deltaCOP1_diTrp_1	157	162	PF00928	0.555
LIG_FHA_1	105	111	PF00498	0.564
LIG_FHA_2	204	210	PF00498	0.504
LIG_FHA_2	447	453	PF00498	0.484
LIG_FHA_2	771	777	PF00498	0.474
LIG_LIR_Apic_2	876	882	PF02991	0.551
LIG_LIR_Gen_1	157	167	PF02991	0.547
LIG_LIR_Nem_3	157	162	PF02991	0.555
LIG_PDZ_Class_1	995	1000	PF00595	0.581
LIG_SH2_STAT5	19	22	PF00017	0.537
LIG_SH2_STAT5	193	196	PF00017	0.484
LIG_SH3_3	896	902	PF00018	0.572
LIG_SH3_3	903	909	PF00018	0.555
LIG_SH3_3	923	929	PF00018	0.526
LIG_SH3_3	977	983	PF00018	0.586
LIG_WW_3	900	904	PF00397	0.571
LIG_WW_3	927	931	PF00397	0.582
LIG_WW_3	981	985	PF00397	0.585
MOD_CDK_SPK_2	115	120	PF00069	0.562
MOD_CDK_SPK_2	149	154	PF00069	0.559
MOD_CK1_1	114	120	PF00069	0.564
MOD_CK1_1	74	80	PF00069	0.616
MOD_CK2_1	887	893	PF00069	0.589
MOD_CK2_1	914	920	PF00069	0.585
MOD_CK2_1	941	947	PF00069	0.600
MOD_CK2_1	968	974	PF00069	0.597
MOD_Cter_Amidation	82	85	PF01082	0.550
MOD_DYRK1A_RPxSP_1	149	153	PF00069	0.557
MOD_GlcNHglycan	211	214	PF01048	0.512
MOD_GlcNHglycan	238	241	PF01048	0.501
MOD_GlcNHglycan	265	268	PF01048	0.490
MOD_GlcNHglycan	292	295	PF01048	0.477
MOD_GlcNHglycan	319	322	PF01048	0.534
MOD_GlcNHglycan	346	349	PF01048	0.597
MOD_GlcNHglycan	373	376	PF01048	0.473
MOD_GlcNHglycan	400	403	PF01048	0.462
MOD_GlcNHglycan	427	430	PF01048	0.465
MOD_GlcNHglycan	454	457	PF01048	0.493
MOD_GlcNHglycan	481	484	PF01048	0.571
MOD_GlcNHglycan	508	511	PF01048	0.513
MOD_GlcNHglycan	535	538	PF01048	0.509
MOD_GlcNHglycan	562	565	PF01048	0.505
MOD_GlcNHglycan	589	592	PF01048	0.507
MOD_GlcNHglycan	616	619	PF01048	0.505
MOD_GlcNHglycan	643	646	PF01048	0.433
MOD_GlcNHglycan	670	673	PF01048	0.445
MOD_GlcNHglycan	697	700	PF01048	0.440
MOD_GlcNHglycan	724	727	PF01048	0.450
MOD_GlcNHglycan	751	754	PF01048	0.452
MOD_GlcNHglycan	778	781	PF01048	0.456
MOD_GlcNHglycan	805	808	PF01048	0.471
MOD_GlcNHglycan	832	835	PF01048	0.488
MOD_GlcNHglycan	859	862	PF01048	0.528
MOD_GlcNHglycan	903	906	PF01048	0.614
MOD_GlcNHglycan	930	933	PF01048	0.600
MOD_GlcNHglycan	957	960	PF01048	0.599
MOD_GlcNHglycan	984	987	PF01048	0.597
MOD_GSK3_1	111	118	PF00069	0.575
MOD_GSK3_1	194	201	PF00069	0.688
MOD_GSK3_1	20	27	PF00069	0.521
MOD_GSK3_1	205	212	PF00069	0.523
MOD_GSK3_1	217	224	PF00069	0.455
MOD_GSK3_1	232	239	PF00069	0.420
MOD_GSK3_1	259	266	PF00069	0.494
MOD_GSK3_1	271	278	PF00069	0.442
MOD_GSK3_1	286	293	PF00069	0.453
MOD_GSK3_1	298	305	PF00069	0.410
MOD_GSK3_1	313	320	PF00069	0.407
MOD_GSK3_1	340	347	PF00069	0.483
MOD_GSK3_1	352	359	PF00069	0.399
MOD_GSK3_1	367	374	PF00069	0.487
MOD_GSK3_1	394	401	PF00069	0.430
MOD_GSK3_1	406	413	PF00069	0.390
MOD_GSK3_1	421	428	PF00069	0.390
MOD_GSK3_1	433	440	PF00069	0.384
MOD_GSK3_1	448	455	PF00069	0.431
MOD_GSK3_1	460	467	PF00069	0.382
MOD_GSK3_1	475	482	PF00069	0.420
MOD_GSK3_1	487	494	PF00069	0.390
MOD_GSK3_1	502	509	PF00069	0.477
MOD_GSK3_1	514	521	PF00069	0.498
MOD_GSK3_1	529	536	PF00069	0.500
MOD_GSK3_1	541	548	PF00069	0.496
MOD_GSK3_1	556	563	PF00069	0.498
MOD_GSK3_1	583	590	PF00069	0.435
MOD_GSK3_1	595	602	PF00069	0.458
MOD_GSK3_1	610	617	PF00069	0.493
MOD_GSK3_1	622	629	PF00069	0.492
MOD_GSK3_1	637	644	PF00069	0.452
MOD_GSK3_1	649	656	PF00069	0.412
MOD_GSK3_1	664	671	PF00069	0.409
MOD_GSK3_1	691	698	PF00069	0.406
MOD_GSK3_1	703	710	PF00069	0.372
MOD_GSK3_1	71	78	PF00069	0.698
MOD_GSK3_1	718	725	PF00069	0.413
MOD_GSK3_1	730	737	PF00069	0.373
MOD_GSK3_1	745	752	PF00069	0.373
MOD_GSK3_1	757	764	PF00069	0.375
MOD_GSK3_1	772	779	PF00069	0.377
MOD_GSK3_1	784	791	PF00069	0.384
MOD_GSK3_1	799	806	PF00069	0.434
MOD_GSK3_1	811	818	PF00069	0.397
MOD_GSK3_1	826	833	PF00069	0.408
MOD_GSK3_1	838	845	PF00069	0.414
MOD_GSK3_1	853	860	PF00069	0.493
MOD_GSK3_1	865	872	PF00069	0.465
MOD_GSK3_1	883	890	PF00069	0.548
MOD_GSK3_1	910	917	PF00069	0.600
MOD_GSK3_1	937	944	PF00069	0.602
MOD_GSK3_1	964	971	PF00069	0.598
MOD_GSK3_1	991	998	PF00069	0.583
MOD_N-GLC_1	47	52	PF02516	0.542
MOD_N-GLC_1	955	960	PF02516	0.599
MOD_PIKK_1	174	180	PF00454	0.544
MOD_PKA_1	142	148	PF00069	0.582
MOD_PKA_2	114	120	PF00069	0.564
MOD_PKA_2	142	148	PF00069	0.582
MOD_PKA_2	217	223	PF00069	0.512
MOD_PKA_2	244	250	PF00069	0.463
MOD_PKA_2	271	277	PF00069	0.668
MOD_PKA_2	298	304	PF00069	0.475
MOD_PKA_2	325	331	PF00069	0.449
MOD_PKA_2	352	358	PF00069	0.463
MOD_PKA_2	379	385	PF00069	0.489
MOD_PKA_2	406	412	PF00069	0.454
MOD_PKA_2	433	439	PF00069	0.449
MOD_PKA_2	460	466	PF00069	0.448
MOD_PKA_2	487	493	PF00069	0.443
MOD_PKA_2	514	520	PF00069	0.383
MOD_PKA_2	541	547	PF00069	0.380
MOD_PKA_2	568	574	PF00069	0.376
MOD_PKA_2	595	601	PF00069	0.377
MOD_PKA_2	622	628	PF00069	0.377
MOD_PKA_2	649	655	PF00069	0.376
MOD_PKA_2	676	682	PF00069	0.431
MOD_PKA_2	703	709	PF00069	0.437
MOD_PKA_2	730	736	PF00069	0.438
MOD_PKA_2	757	763	PF00069	0.440
MOD_PKA_2	784	790	PF00069	0.449
MOD_PKA_2	811	817	PF00069	0.462
MOD_PKA_2	838	844	PF00069	0.479
MOD_PKA_2	865	871	PF00069	0.532
MOD_PKB_1	140	148	PF00069	0.581
MOD_PKB_1	885	893	PF00069	0.588
MOD_PKB_1	912	920	PF00069	0.585
MOD_PKB_1	939	947	PF00069	0.601
MOD_PKB_1	966	974	PF00069	0.598
MOD_ProDKin_1	115	121	PF00069	0.561
MOD_ProDKin_1	126	132	PF00069	0.512
MOD_ProDKin_1	149	155	PF00069	0.558
MOD_ProDKin_1	895	901	PF00069	0.570
MOD_ProDKin_1	922	928	PF00069	0.582
MOD_ProDKin_1	949	955	PF00069	0.595
MOD_ProDKin_1	976	982	PF00069	0.586
TRG_ER_diArg_1	169	171	PF00400	0.556
TRG_ER_diArg_1	42	44	PF00400	0.536
TRG_ER_diArg_1	66	68	PF00400	0.584
TRG_ER_diArg_1	79	82	PF00400	0.561
TRG_ER_diArg_1	884	887	PF00400	0.631
TRG_ER_diArg_1	911	914	PF00400	0.622
TRG_ER_diArg_1	938	941	PF00400	0.606
TRG_ER_diArg_1	965	968	PF00400	0.602
TRG_ER_diArg_1	992	995	PF00400	0.593
TRG_Pf-PMV_PEXEL_1	170	175	PF00026	0.553
TRG_Pf-PMV_PEXEL_1	186	191	PF00026	0.460
TRG_PTS2	1	14	PF00400	0.533

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IDF5	Leishmania donovani	46%	100%
A0A451EJD8	Leishmania donovani	65%	100%