LeishMANIAdb
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DNA repair protein BRCA2, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA repair protein BRCA2, putative
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WVQ6_LEIDO
TriTrypDb:
LdBPK_200070.1 * , LdCL_200005600 , LDHU3_20.0080
Length:
1165

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005654 nucleoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S7WVQ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVQ6

PDB structure(s): 7qv8_D

Function

Biological processes
Term Name Level Count
GO:0000724 double-strand break repair via homologous recombination 7 11
GO:0000725 recombinational repair 6 11
GO:0006139 nucleobase-containing compound metabolic process 3 11
GO:0006259 DNA metabolic process 4 11
GO:0006281 DNA repair 5 11
GO:0006302 double-strand break repair 6 11
GO:0006310 DNA recombination 5 11
GO:0006725 cellular aromatic compound metabolic process 3 11
GO:0006807 nitrogen compound metabolic process 2 11
GO:0006950 response to stress 2 11
GO:0006974 DNA damage response 4 11
GO:0008152 metabolic process 1 11
GO:0009987 cellular process 1 11
GO:0033554 cellular response to stress 3 11
GO:0034641 cellular nitrogen compound metabolic process 3 11
GO:0043170 macromolecule metabolic process 3 11
GO:0044237 cellular metabolic process 2 11
GO:0044238 primary metabolic process 2 11
GO:0044260 obsolete cellular macromolecule metabolic process 3 11
GO:0046483 heterocycle metabolic process 3 11
GO:0050896 response to stimulus 1 11
GO:0051716 cellular response to stimulus 2 11
GO:0071704 organic substance metabolic process 2 11
GO:0090304 nucleic acid metabolic process 4 11
GO:1901360 organic cyclic compound metabolic process 3 11
GO:0006355 regulation of DNA-templated transcription 6 1
GO:0009605 response to external stimulus 2 1
GO:0009607 response to biotic stimulus 2 1
GO:0009889 regulation of biosynthetic process 4 1
GO:0010468 regulation of gene expression 5 1
GO:0010556 regulation of macromolecule biosynthetic process 5 1
GO:0019219 regulation of nucleobase-containing compound metabolic process 5 1
GO:0019222 regulation of metabolic process 3 1
GO:0020033 antigenic variation 7 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0031326 regulation of cellular biosynthetic process 5 1
GO:0042783 evasion of host immune response 6 1
GO:0043207 response to external biotic stimulus 3 1
GO:0044403 biological process involved in symbiotic interaction 2 1
GO:0044419 biological process involved in interspecies interaction between organisms 1 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051252 regulation of RNA metabolic process 5 1
GO:0051701 biological process involved in interaction with host 3 1
GO:0051707 response to other organism 2 1
GO:0052173 response to defenses of other organism 3 1
GO:0052200 response to host defenses 4 1
GO:0052572 response to host immune response 5 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0075136 response to host 3 1
GO:0080090 regulation of primary metabolic process 4 1
GO:1903506 regulation of nucleic acid-templated transcription 7 1
GO:2001141 regulation of RNA biosynthetic process 6 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 1
GO:0003677 DNA binding 4 1
GO:0003684 damaged DNA binding 5 1
GO:0005488 binding 1 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901363 heterocyclic compound binding 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 171 175 PF00656 0.445
CLV_C14_Caspase3-7 33 37 PF00656 0.605
CLV_C14_Caspase3-7 460 464 PF00656 0.536
CLV_C14_Caspase3-7 729 733 PF00656 0.289
CLV_C14_Caspase3-7 873 877 PF00656 0.567
CLV_NRD_NRD_1 1083 1085 PF00675 0.524
CLV_NRD_NRD_1 124 126 PF00675 0.353
CLV_NRD_NRD_1 269 271 PF00675 0.585
CLV_NRD_NRD_1 27 29 PF00675 0.509
CLV_NRD_NRD_1 426 428 PF00675 0.336
CLV_NRD_NRD_1 45 47 PF00675 0.578
CLV_NRD_NRD_1 608 610 PF00675 0.498
CLV_NRD_NRD_1 712 714 PF00675 0.543
CLV_NRD_NRD_1 846 848 PF00675 0.438
CLV_NRD_NRD_1 995 997 PF00675 0.550
CLV_PCSK_FUR_1 606 610 PF00082 0.496
CLV_PCSK_KEX2_1 1020 1022 PF00082 0.427
CLV_PCSK_KEX2_1 1083 1085 PF00082 0.465
CLV_PCSK_KEX2_1 124 126 PF00082 0.353
CLV_PCSK_KEX2_1 163 165 PF00082 0.645
CLV_PCSK_KEX2_1 269 271 PF00082 0.612
CLV_PCSK_KEX2_1 29 31 PF00082 0.512
CLV_PCSK_KEX2_1 608 610 PF00082 0.637
CLV_PCSK_KEX2_1 712 714 PF00082 0.531
CLV_PCSK_KEX2_1 995 997 PF00082 0.524
CLV_PCSK_PC1ET2_1 1020 1022 PF00082 0.367
CLV_PCSK_PC1ET2_1 163 165 PF00082 0.517
CLV_PCSK_PC1ET2_1 29 31 PF00082 0.500
CLV_PCSK_PC7_1 25 31 PF00082 0.504
CLV_PCSK_SKI1_1 1093 1097 PF00082 0.478
CLV_PCSK_SKI1_1 119 123 PF00082 0.318
CLV_PCSK_SKI1_1 157 161 PF00082 0.645
CLV_PCSK_SKI1_1 246 250 PF00082 0.516
CLV_PCSK_SKI1_1 312 316 PF00082 0.608
CLV_PCSK_SKI1_1 376 380 PF00082 0.370
CLV_PCSK_SKI1_1 423 427 PF00082 0.297
CLV_PCSK_SKI1_1 457 461 PF00082 0.289
CLV_PCSK_SKI1_1 497 501 PF00082 0.261
CLV_PCSK_SKI1_1 589 593 PF00082 0.534
CLV_PCSK_SKI1_1 651 655 PF00082 0.585
CLV_PCSK_SKI1_1 691 695 PF00082 0.425
CLV_PCSK_SKI1_1 824 828 PF00082 0.467
CLV_Separin_Metazoa 1011 1015 PF03568 0.483
CLV_Separin_Metazoa 1145 1149 PF03568 0.493
DEG_APCC_DBOX_1 124 132 PF00400 0.496
DEG_APCC_DBOX_1 210 218 PF00400 0.524
DEG_APCC_DBOX_1 422 430 PF00400 0.279
DEG_APCC_DBOX_1 780 788 PF00400 0.466
DEG_COP1_1 142 150 PF00400 0.569
DEG_COP1_1 873 883 PF00400 0.592
DEG_Nend_UBRbox_1 1 4 PF02207 0.574
DEG_SCF_FBW7_1 314 319 PF00400 0.412
DEG_SPOP_SBC_1 181 185 PF00917 0.614
DOC_ANK_TNKS_1 426 433 PF00023 0.475
DOC_CDC14_PxL_1 102 110 PF14671 0.573
DOC_CKS1_1 527 532 PF01111 0.595
DOC_CKS1_1 80 85 PF01111 0.543
DOC_CKS1_1 938 943 PF01111 0.683
DOC_CYCLIN_yCln2_LP_2 1001 1007 PF00134 0.636
DOC_CYCLIN_yCln2_LP_2 1101 1107 PF00134 0.470
DOC_CYCLIN_yCln2_LP_2 539 545 PF00134 0.455
DOC_CYCLIN_yCln2_LP_2 772 778 PF00134 0.309
DOC_CYCLIN_yCln2_LP_2 938 944 PF00134 0.575
DOC_MAPK_DCC_7 875 885 PF00069 0.591
DOC_MAPK_gen_1 1083 1090 PF00069 0.503
DOC_MAPK_gen_1 17 26 PF00069 0.539
DOC_MAPK_MEF2A_6 17 26 PF00069 0.574
DOC_MAPK_RevD_3 1069 1084 PF00069 0.440
DOC_PP1_RVXF_1 1076 1083 PF00149 0.436
DOC_PP1_RVXF_1 689 695 PF00149 0.478
DOC_PP2B_LxvP_1 138 141 PF13499 0.584
DOC_PP2B_LxvP_1 205 208 PF13499 0.509
DOC_PP2B_LxvP_1 539 542 PF13499 0.455
DOC_PP2B_LxvP_1 761 764 PF13499 0.480
DOC_PP2B_LxvP_1 772 775 PF13499 0.388
DOC_PP4_FxxP_1 11 14 PF00568 0.531
DOC_PP4_FxxP_1 272 275 PF00568 0.605
DOC_USP7_MATH_1 169 173 PF00917 0.662
DOC_USP7_MATH_1 182 186 PF00917 0.785
DOC_USP7_MATH_1 228 232 PF00917 0.805
DOC_USP7_MATH_1 316 320 PF00917 0.492
DOC_USP7_MATH_1 378 382 PF00917 0.499
DOC_USP7_MATH_1 396 400 PF00917 0.472
DOC_USP7_MATH_1 50 54 PF00917 0.588
DOC_USP7_MATH_1 619 623 PF00917 0.542
DOC_USP7_MATH_1 63 67 PF00917 0.757
DOC_USP7_MATH_1 677 681 PF00917 0.427
DOC_USP7_MATH_1 764 768 PF00917 0.449
DOC_USP7_MATH_1 894 898 PF00917 0.719
DOC_USP7_MATH_1 899 903 PF00917 0.737
DOC_USP7_MATH_1 967 971 PF00917 0.696
DOC_WW_Pin1_4 1100 1105 PF00397 0.559
DOC_WW_Pin1_4 312 317 PF00397 0.534
DOC_WW_Pin1_4 35 40 PF00397 0.654
DOC_WW_Pin1_4 363 368 PF00397 0.453
DOC_WW_Pin1_4 399 404 PF00397 0.544
DOC_WW_Pin1_4 450 455 PF00397 0.540
DOC_WW_Pin1_4 46 51 PF00397 0.651
DOC_WW_Pin1_4 52 57 PF00397 0.609
DOC_WW_Pin1_4 526 531 PF00397 0.516
DOC_WW_Pin1_4 573 578 PF00397 0.456
DOC_WW_Pin1_4 58 63 PF00397 0.623
DOC_WW_Pin1_4 79 84 PF00397 0.696
DOC_WW_Pin1_4 892 897 PF00397 0.737
DOC_WW_Pin1_4 937 942 PF00397 0.620
LIG_14-3-3_CanoR_1 1093 1101 PF00244 0.421
LIG_14-3-3_CanoR_1 1151 1159 PF00244 0.499
LIG_14-3-3_CanoR_1 213 218 PF00244 0.754
LIG_14-3-3_CanoR_1 236 244 PF00244 0.665
LIG_14-3-3_CanoR_1 457 462 PF00244 0.517
LIG_14-3-3_CanoR_1 589 595 PF00244 0.565
LIG_14-3-3_CanoR_1 627 632 PF00244 0.337
LIG_14-3-3_CanoR_1 770 775 PF00244 0.495
LIG_14-3-3_CanoR_1 781 785 PF00244 0.485
LIG_14-3-3_CanoR_1 817 823 PF00244 0.444
LIG_Actin_WH2_2 1135 1150 PF00022 0.441
LIG_Actin_WH2_2 454 471 PF00022 0.519
LIG_Actin_WH2_2 472 488 PF00022 0.366
LIG_BIR_III_2 36 40 PF00653 0.612
LIG_BIR_III_2 838 842 PF00653 0.475
LIG_BIR_III_4 732 736 PF00653 0.225
LIG_BRCT_BRCA1_1 324 328 PF00533 0.514
LIG_CSL_BTD_1 1116 1119 PF09270 0.478
LIG_CSL_BTD_1 997 1000 PF09270 0.617
LIG_CtBP_PxDLS_1 542 546 PF00389 0.501
LIG_deltaCOP1_diTrp_1 1113 1122 PF00928 0.384
LIG_FHA_1 1000 1006 PF00498 0.571
LIG_FHA_1 1035 1041 PF00498 0.511
LIG_FHA_1 224 230 PF00498 0.799
LIG_FHA_1 286 292 PF00498 0.489
LIG_FHA_1 294 300 PF00498 0.621
LIG_FHA_1 403 409 PF00498 0.487
LIG_FHA_1 469 475 PF00498 0.464
LIG_FHA_1 627 633 PF00498 0.385
LIG_FHA_1 722 728 PF00498 0.532
LIG_FHA_1 745 751 PF00498 0.394
LIG_FHA_1 755 761 PF00498 0.420
LIG_FHA_1 777 783 PF00498 0.418
LIG_FHA_1 810 816 PF00498 0.392
LIG_FHA_1 899 905 PF00498 0.568
LIG_FHA_1 927 933 PF00498 0.584
LIG_FHA_1 938 944 PF00498 0.478
LIG_FHA_2 1006 1012 PF00498 0.641
LIG_FHA_2 1046 1052 PF00498 0.538
LIG_FHA_2 147 153 PF00498 0.646
LIG_FHA_2 169 175 PF00498 0.459
LIG_FHA_2 31 37 PF00498 0.658
LIG_FHA_2 458 464 PF00498 0.536
LIG_FHA_2 505 511 PF00498 0.536
LIG_FHA_2 53 59 PF00498 0.656
LIG_FHA_2 645 651 PF00498 0.593
LIG_FHA_2 791 797 PF00498 0.518
LIG_FHA_2 871 877 PF00498 0.732
LIG_GBD_Chelix_1 924 932 PF00786 0.501
LIG_LIR_Apic_2 10 14 PF02991 0.602
LIG_LIR_Apic_2 1113 1119 PF02991 0.386
LIG_LIR_Gen_1 516 526 PF02991 0.496
LIG_LIR_Gen_1 666 677 PF02991 0.473
LIG_LIR_Gen_1 747 753 PF02991 0.360
LIG_LIR_Gen_1 756 766 PF02991 0.356
LIG_LIR_Gen_1 810 815 PF02991 0.333
LIG_LIR_LC3C_4 436 441 PF02991 0.476
LIG_LIR_LC3C_4 783 786 PF02991 0.344
LIG_LIR_Nem_3 1089 1095 PF02991 0.373
LIG_LIR_Nem_3 399 404 PF02991 0.407
LIG_LIR_Nem_3 516 522 PF02991 0.496
LIG_LIR_Nem_3 666 672 PF02991 0.519
LIG_LIR_Nem_3 747 751 PF02991 0.410
LIG_LIR_Nem_3 756 761 PF02991 0.325
LIG_LIR_Nem_3 810 814 PF02991 0.326
LIG_LIR_Nem_3 850 855 PF02991 0.497
LIG_LIR_Nem_3 976 982 PF02991 0.390
LIG_MYND_1 106 110 PF01753 0.544
LIG_NRBOX 338 344 PF00104 0.372
LIG_Pex14_1 1091 1095 PF04695 0.467
LIG_Pex14_1 669 673 PF04695 0.472
LIG_PTB_Apo_2 752 759 PF02174 0.421
LIG_PTB_Apo_2 785 792 PF02174 0.326
LIG_PTB_Phospho_1 752 758 PF10480 0.426
LIG_Rb_pABgroove_1 983 991 PF01858 0.537
LIG_REV1ctd_RIR_1 691 701 PF16727 0.500
LIG_SH2_CRK 519 523 PF00017 0.536
LIG_SH2_CRK 758 762 PF00017 0.443
LIG_SH2_CRK 811 815 PF00017 0.365
LIG_SH2_CRK 909 913 PF00017 0.477
LIG_SH2_CRK 979 983 PF00017 0.486
LIG_SH2_SRC 701 704 PF00017 0.460
LIG_SH2_STAP1 811 815 PF00017 0.376
LIG_SH2_STAT3 915 918 PF00017 0.634
LIG_SH2_STAT5 1139 1142 PF00017 0.385
LIG_SH2_STAT5 701 704 PF00017 0.464
LIG_SH2_STAT5 811 814 PF00017 0.356
LIG_SH2_STAT5 915 918 PF00017 0.662
LIG_SH3_3 104 110 PF00018 0.509
LIG_SH3_3 195 201 PF00018 0.660
LIG_SH3_3 481 487 PF00018 0.496
LIG_SH3_3 760 766 PF00018 0.473
LIG_SH3_3 878 884 PF00018 0.718
LIG_SH3_3 91 97 PF00018 0.737
LIG_SH3_3 928 934 PF00018 0.597
LIG_SH3_3 938 944 PF00018 0.678
LIG_SH3_3 957 963 PF00018 0.763
LIG_Sin3_3 437 444 PF02671 0.461
LIG_SUMO_SIM_anti_2 296 303 PF11976 0.444
LIG_SUMO_SIM_anti_2 402 408 PF11976 0.390
LIG_SUMO_SIM_anti_2 438 443 PF11976 0.442
LIG_SUMO_SIM_anti_2 629 636 PF11976 0.479
LIG_SUMO_SIM_anti_2 779 786 PF11976 0.470
LIG_SUMO_SIM_par_1 457 463 PF11976 0.525
LIG_SUMO_SIM_par_1 629 636 PF11976 0.492
LIG_TRAF2_1 1055 1058 PF00917 0.434
LIG_TYR_ITIM 517 522 PF00017 0.410
LIG_UBA3_1 359 368 PF00899 0.465
LIG_WRC_WIRS_1 327 332 PF05994 0.379
LIG_WRC_WIRS_1 564 569 PF05994 0.482
MOD_CDK_SPK_2 363 368 PF00069 0.409
MOD_CDK_SPK_2 79 84 PF00069 0.531
MOD_CDK_SPxxK_3 450 457 PF00069 0.342
MOD_CK1_1 1029 1035 PF00069 0.582
MOD_CK1_1 114 120 PF00069 0.449
MOD_CK1_1 172 178 PF00069 0.672
MOD_CK1_1 190 196 PF00069 0.677
MOD_CK1_1 297 303 PF00069 0.545
MOD_CK1_1 319 325 PF00069 0.415
MOD_CK1_1 38 44 PF00069 0.688
MOD_CK1_1 399 405 PF00069 0.466
MOD_CK1_1 435 441 PF00069 0.406
MOD_CK1_1 445 451 PF00069 0.218
MOD_CK1_1 51 57 PF00069 0.619
MOD_CK1_1 61 67 PF00069 0.606
MOD_CK1_1 626 632 PF00069 0.398
MOD_CK1_1 668 674 PF00069 0.462
MOD_CK1_1 952 958 PF00069 0.708
MOD_CK2_1 1005 1011 PF00069 0.623
MOD_CK2_1 1045 1051 PF00069 0.443
MOD_CK2_1 1155 1161 PF00069 0.562
MOD_CK2_1 146 152 PF00069 0.653
MOD_CK2_1 248 254 PF00069 0.639
MOD_CK2_1 343 349 PF00069 0.457
MOD_CK2_1 443 449 PF00069 0.286
MOD_CK2_1 504 510 PF00069 0.348
MOD_CK2_1 52 58 PF00069 0.652
MOD_CK2_1 644 650 PF00069 0.481
MOD_Cter_Amidation 44 47 PF01082 0.722
MOD_DYRK1A_RPxSP_1 312 316 PF00069 0.443
MOD_GlcNHglycan 1028 1031 PF01048 0.583
MOD_GlcNHglycan 1129 1132 PF01048 0.396
MOD_GlcNHglycan 1142 1145 PF01048 0.500
MOD_GlcNHglycan 116 119 PF01048 0.363
MOD_GlcNHglycan 184 187 PF01048 0.658
MOD_GlcNHglycan 189 192 PF01048 0.676
MOD_GlcNHglycan 279 282 PF01048 0.674
MOD_GlcNHglycan 296 299 PF01048 0.655
MOD_GlcNHglycan 345 348 PF01048 0.483
MOD_GlcNHglycan 380 383 PF01048 0.437
MOD_GlcNHglycan 393 396 PF01048 0.611
MOD_GlcNHglycan 398 401 PF01048 0.382
MOD_GlcNHglycan 435 438 PF01048 0.394
MOD_GlcNHglycan 766 769 PF01048 0.536
MOD_GlcNHglycan 84 87 PF01048 0.728
MOD_GlcNHglycan 859 863 PF01048 0.638
MOD_GlcNHglycan 89 92 PF01048 0.735
MOD_GlcNHglycan 896 899 PF01048 0.662
MOD_GlcNHglycan 934 937 PF01048 0.624
MOD_GlcNHglycan 951 954 PF01048 0.788
MOD_GSK3_1 1041 1048 PF00069 0.546
MOD_GSK3_1 1069 1076 PF00069 0.518
MOD_GSK3_1 108 115 PF00069 0.307
MOD_GSK3_1 1151 1158 PF00069 0.512
MOD_GSK3_1 146 153 PF00069 0.553
MOD_GSK3_1 168 175 PF00069 0.512
MOD_GSK3_1 242 249 PF00069 0.741
MOD_GSK3_1 293 300 PF00069 0.548
MOD_GSK3_1 310 317 PF00069 0.355
MOD_GSK3_1 318 325 PF00069 0.424
MOD_GSK3_1 326 333 PF00069 0.445
MOD_GSK3_1 343 350 PF00069 0.530
MOD_GSK3_1 387 394 PF00069 0.478
MOD_GSK3_1 445 452 PF00069 0.433
MOD_GSK3_1 46 53 PF00069 0.758
MOD_GSK3_1 54 61 PF00069 0.781
MOD_GSK3_1 563 570 PF00069 0.440
MOD_GSK3_1 619 626 PF00069 0.507
MOD_GSK3_1 70 77 PF00069 0.743
MOD_GSK3_1 716 723 PF00069 0.589
MOD_GSK3_1 776 783 PF00069 0.421
MOD_GSK3_1 866 873 PF00069 0.665
MOD_GSK3_1 894 901 PF00069 0.611
MOD_LATS_1 1149 1155 PF00433 0.510
MOD_LATS_1 455 461 PF00433 0.406
MOD_N-GLC_1 720 725 PF02516 0.476
MOD_N-GLC_1 754 759 PF02516 0.432
MOD_N-GLC_1 787 792 PF02516 0.330
MOD_N-GLC_2 373 375 PF02516 0.357
MOD_NEK2_1 1005 1010 PF00069 0.620
MOD_NEK2_1 1095 1100 PF00069 0.360
MOD_NEK2_1 112 117 PF00069 0.309
MOD_NEK2_1 1138 1143 PF00069 0.493
MOD_NEK2_1 150 155 PF00069 0.601
MOD_NEK2_1 189 194 PF00069 0.554
MOD_NEK2_1 248 253 PF00069 0.752
MOD_NEK2_1 293 298 PF00069 0.598
MOD_NEK2_1 326 331 PF00069 0.532
MOD_NEK2_1 343 348 PF00069 0.510
MOD_NEK2_1 442 447 PF00069 0.348
MOD_NEK2_1 692 697 PF00069 0.454
MOD_NEK2_1 787 792 PF00069 0.462
MOD_NEK2_1 815 820 PF00069 0.537
MOD_NEK2_1 866 871 PF00069 0.748
MOD_PIKK_1 64 70 PF00454 0.633
MOD_PIKK_1 816 822 PF00454 0.512
MOD_PKA_1 124 130 PF00069 0.417
MOD_PKA_2 1026 1032 PF00069 0.617
MOD_PKA_2 124 130 PF00069 0.420
MOD_PKA_2 235 241 PF00069 0.686
MOD_PKA_2 277 283 PF00069 0.785
MOD_PKA_2 626 632 PF00069 0.358
MOD_PKA_2 780 786 PF00069 0.402
MOD_PKA_2 816 822 PF00069 0.512
MOD_PKB_1 211 219 PF00069 0.581
MOD_PKB_1 28 36 PF00069 0.577
MOD_Plk_1 1040 1046 PF00069 0.445
MOD_Plk_1 1069 1075 PF00069 0.493
MOD_Plk_1 169 175 PF00069 0.537
MOD_Plk_1 30 36 PF00069 0.556
MOD_Plk_1 754 760 PF00069 0.425
MOD_Plk_1 787 793 PF00069 0.359
MOD_Plk_1 809 815 PF00069 0.453
MOD_Plk_2-3 1155 1161 PF00069 0.504
MOD_Plk_4 1041 1047 PF00069 0.471
MOD_Plk_4 1058 1064 PF00069 0.521
MOD_Plk_4 108 114 PF00069 0.318
MOD_Plk_4 1086 1092 PF00069 0.439
MOD_Plk_4 146 152 PF00069 0.512
MOD_Plk_4 297 303 PF00069 0.576
MOD_Plk_4 322 328 PF00069 0.490
MOD_Plk_4 402 408 PF00069 0.370
MOD_Plk_4 435 441 PF00069 0.289
MOD_Plk_4 495 501 PF00069 0.427
MOD_Plk_4 541 547 PF00069 0.483
MOD_Plk_4 563 569 PF00069 0.428
MOD_Plk_4 627 633 PF00069 0.362
MOD_Plk_4 665 671 PF00069 0.372
MOD_Plk_4 7 13 PF00069 0.557
MOD_Plk_4 780 786 PF00069 0.368
MOD_Plk_4 787 793 PF00069 0.312
MOD_Plk_4 899 905 PF00069 0.508
MOD_ProDKin_1 1100 1106 PF00069 0.561
MOD_ProDKin_1 312 318 PF00069 0.525
MOD_ProDKin_1 35 41 PF00069 0.659
MOD_ProDKin_1 363 369 PF00069 0.455
MOD_ProDKin_1 399 405 PF00069 0.544
MOD_ProDKin_1 450 456 PF00069 0.415
MOD_ProDKin_1 46 52 PF00069 0.645
MOD_ProDKin_1 526 532 PF00069 0.383
MOD_ProDKin_1 573 579 PF00069 0.460
MOD_ProDKin_1 58 64 PF00069 0.624
MOD_ProDKin_1 79 85 PF00069 0.697
MOD_ProDKin_1 892 898 PF00069 0.738
MOD_ProDKin_1 937 943 PF00069 0.622
TRG_DiLeu_BaEn_1 780 785 PF01217 0.369
TRG_DiLeu_BaEn_4 1041 1047 PF01217 0.398
TRG_DiLeu_BaEn_4 510 516 PF01217 0.270
TRG_DiLeu_BaLyEn_6 1148 1153 PF01217 0.489
TRG_DiLeu_BaLyEn_6 22 27 PF01217 0.579
TRG_ENDOCYTIC_2 1139 1142 PF00928 0.349
TRG_ENDOCYTIC_2 519 522 PF00928 0.410
TRG_ENDOCYTIC_2 758 761 PF00928 0.352
TRG_ENDOCYTIC_2 811 814 PF00928 0.368
TRG_ENDOCYTIC_2 909 912 PF00928 0.482
TRG_ENDOCYTIC_2 979 982 PF00928 0.486
TRG_ER_diArg_1 1082 1084 PF00400 0.436
TRG_ER_diArg_1 123 125 PF00400 0.385
TRG_ER_diArg_1 211 214 PF00400 0.705
TRG_ER_diArg_1 27 30 PF00400 0.508
TRG_ER_diArg_1 587 590 PF00400 0.565
TRG_ER_diArg_1 606 609 PF00400 0.497
TRG_ER_diArg_1 711 713 PF00400 0.539
TRG_Pf-PMV_PEXEL_1 1151 1155 PF00026 0.490
TRG_Pf-PMV_PEXEL_1 651 656 PF00026 0.605
TRG_Pf-PMV_PEXEL_1 834 838 PF00026 0.461
TRG_Pf-PMV_PEXEL_1 853 857 PF00026 0.279

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PAP2 Leptomonas seymouri 51% 95%
A0A1X0NWJ4 Trypanosomatidae 28% 100%
A0A422N7U4 Trypanosoma rangeli 30% 100%
A4HBH5 Leishmania braziliensis 74% 100%
A4HYJ9 Leishmania infantum 100% 100%
C9ZHU4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
E9AUE6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4QD38 Leishmania major 91% 100%
V5BQX8 Trypanosoma cruzi 29% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS