LeishMANIAdb
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ELMO/CED-12 family, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ELMO/CED-12 family, putative
Gene product:
ELMO/CED-12 family, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WVN6_LEIDO
TriTrypDb:
LdBPK_191600.1 , LdCL_190021800 , LDHU3_19.1940
Length:
248

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WVN6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVN6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_SKI1_1 148 152 PF00082 0.332
CLV_PCSK_SKI1_1 181 185 PF00082 0.320
CLV_PCSK_SKI1_1 233 237 PF00082 0.438
CLV_PCSK_SKI1_1 71 75 PF00082 0.398
DEG_Nend_UBRbox_2 1 3 PF02207 0.460
DOC_CKS1_1 131 136 PF01111 0.332
DOC_CKS1_1 6 11 PF01111 0.422
DOC_MAPK_gen_1 212 220 PF00069 0.355
DOC_MAPK_MEF2A_6 181 190 PF00069 0.282
DOC_PP1_RVXF_1 231 237 PF00149 0.430
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I9A9 Leptomonas seymouri 61% 66%
A0A0S4IWN1 Bodo saltans 34% 73%
A0A1X0P699 Trypanosomatidae 39% 85%
A4HAA6 Leishmania braziliensis 76% 100%
A4HYI6 Leishmania infantum 100% 100%
E9ASB0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
Q08DZ3 Bos taurus 25% 85%
Q0IIE6 Bos taurus 22% 76%
Q3V1U8 Mus musculus 22% 76%
Q4QD52 Leishmania major 96% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS