MBOAT, membrane-bound O-acyltransferase family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glycerol uptake protein, putative (fragment)

Species:

Leishmania donovani

UniProt:

A0A3S7WVK4_LEIDO

TriTrypDb:

LdBPK_191350.1 , LdCL_190018800 , LDHU3_19.1630

Length:

777

Annotations

LeishMANIAdb annotations

Membrane-bound O-acyltransferase involved in the remodeling of glycosylphosphatidylinositol (GPI) anchors. Related to fungal GUP1 proteins.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 30
NetGPI	no	yes: 0, no: 30

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	4
GO:0005783	endoplasmic reticulum	5	4
GO:0016020	membrane	2	31
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043231	intracellular membrane-bounded organelle	4	4
GO:0110165	cellular anatomical entity	1	31

Previous1Next

Expansion

Sequence features

A0A3S7WVK4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVK4

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	6
GO:0016740	transferase activity	2	6
GO:0016746	acyltransferase activity	3	6

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	302	306	PF00656	0.362
CLV_C14_Caspase3-7	721	725	PF00656	0.403
CLV_NRD_NRD_1	228	230	PF00675	0.392
CLV_NRD_NRD_1	459	461	PF00675	0.328
CLV_NRD_NRD_1	541	543	PF00675	0.287
CLV_NRD_NRD_1	629	631	PF00675	0.396
CLV_NRD_NRD_1	657	659	PF00675	0.410
CLV_NRD_NRD_1	670	672	PF00675	0.351
CLV_PCSK_KEX2_1	147	149	PF00082	0.235
CLV_PCSK_KEX2_1	227	229	PF00082	0.371

Previous1 2 3 4 5…29Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IRP6	Bodo saltans	35%	100%
A0A1X0P614	Trypanosomatidae	34%	100%
A0A1X0P616	Trypanosomatidae	41%	100%
A0A3Q8IAC1	Leishmania donovani	97%	100%
A0A3Q8IBC3	Leishmania donovani	88%	99%
A0A3Q8IBE0	Leishmania donovani	74%	100%
A0A3Q8IDD7	Leishmania donovani	97%	100%
A0A3S5H769	Leishmania donovani	97%	100%
A0A3S5IRW9	Trypanosoma rangeli	35%	100%
A0A3S7WVJ2	Leishmania donovani	74%	100%

Previous1 2 3Next