LeishMANIAdb
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WW domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
WW domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WVD7_LEIDO
TriTrypDb:
LdBPK_190520.1 * , LdCL_190010200 , LDHU3_19.0580
Length:
569

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WVD7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVD7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 24 28 PF00656 0.556
CLV_C14_Caspase3-7 470 474 PF00656 0.533
CLV_NRD_NRD_1 142 144 PF00675 0.596
CLV_NRD_NRD_1 176 178 PF00675 0.389
CLV_NRD_NRD_1 214 216 PF00675 0.486
CLV_NRD_NRD_1 287 289 PF00675 0.551
CLV_NRD_NRD_1 290 292 PF00675 0.542
CLV_NRD_NRD_1 331 333 PF00675 0.483
CLV_NRD_NRD_1 433 435 PF00675 0.457
CLV_NRD_NRD_1 436 438 PF00675 0.437
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I9S0 Leptomonas seymouri 46% 95%
A0A1X0P7R9 Trypanosomatidae 33% 100%
A0A422P367 Trypanosoma rangeli 34% 100%
A4HA10 Leishmania braziliensis 67% 100%
A4HY74 Leishmania infantum 100% 100%
D0A0J3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AS04 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
Q4QDG9 Leishmania major 91% 100%
V5BSD1 Trypanosoma cruzi 36% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS