Ribosomal S13/S15 N-terminal domain family protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S13, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WVA6_LEIDO

TriTrypDb:

LdBPK_333300.1 , LdCL_190008900 , LDHU3_33.4780

Length:

151

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 12

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 15
NetGPI	no	yes: 0, no: 15

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Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0005840	ribosome	5	15
GO:0015935	small ribosomal subunit	4	1
GO:0016020	membrane	2	1
GO:0022627	cytosolic small ribosomal subunit	5	1
GO:0032991	protein-containing complex	1	15
GO:0035869	ciliary transition zone	2	1
GO:0043226	organelle	2	16
GO:0043228	non-membrane-bounded organelle	3	16
GO:0043229	intracellular organelle	3	16

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Expansion

Sequence features

A0A3S7WVA6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WVA6

PDB structure(s): 6az1_T

Function

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Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	16
GO:0006518	peptide metabolic process	4	16
GO:0006807	nitrogen compound metabolic process	2	16
GO:0008152	metabolic process	1	16
GO:0009058	biosynthetic process	2	16
GO:0009059	macromolecule biosynthetic process	4	16
GO:0009987	cellular process	1	16
GO:0019538	protein metabolic process	3	16
GO:0034641	cellular nitrogen compound metabolic process	3	16
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	16

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0003735	structural constituent of ribosome	2	16
GO:0005198	structural molecule activity	1	16
GO:0005488	binding	1	1
GO:0019843	rRNA binding	5	1
GO:0070181	small ribosomal subunit rRNA binding	6	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	53	57	PF00656	0.416
CLV_NRD_NRD_1	19	21	PF00675	0.301
CLV_NRD_NRD_1	41	43	PF00675	0.357
CLV_NRD_NRD_1	68	70	PF00675	0.512
CLV_NRD_NRD_1	98	100	PF00675	0.274
CLV_PCSK_KEX2_1	130	132	PF00082	0.288
CLV_PCSK_KEX2_1	19	21	PF00082	0.301
CLV_PCSK_KEX2_1	93	95	PF00082	0.277
CLV_PCSK_PC1ET2_1	130	132	PF00082	0.317
CLV_PCSK_PC1ET2_1	93	95	PF00082	0.266

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYB7	Leptomonas seymouri	95%	100%
A0A0S4IT71	Bodo saltans	77%	100%
A0A0S4J1V6	Bodo saltans	79%	100%
A0A1D8PPE0	Candida albicans (strain SC5314 / ATCC MYA-2876)	63%	100%
A0A1X0NRE5	Trypanosomatidae	85%	100%
A0A3R7M2N1	Trypanosoma rangeli	77%	100%
A0A3R7P3J7	Trypanosoma rangeli	82%	100%
A0A3S7X790	Leishmania donovani	99%	100%
A0B5E6	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	32%	89%
A0RTT1	Cenarchaeum symbiosum (strain A)	36%	100%

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