LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7WV31_LEIDO
TriTrypDb:
LdBPK_180640.1 , LdCL_180011500 , LDHU3_18.0840
Length:
562

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WV31
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WV31

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 43 47 PF00656 0.724
CLV_NRD_NRD_1 10 12 PF00675 0.769
CLV_NRD_NRD_1 133 135 PF00675 0.678
CLV_NRD_NRD_1 173 175 PF00675 0.680
CLV_NRD_NRD_1 187 189 PF00675 0.707
CLV_NRD_NRD_1 330 332 PF00675 0.720
CLV_NRD_NRD_1 352 354 PF00675 0.740
CLV_NRD_NRD_1 37 39 PF00675 0.753
CLV_NRD_NRD_1 382 384 PF00675 0.826
CLV_NRD_NRD_1 450 452 PF00675 0.709
CLV_NRD_NRD_1 495 497 PF00675 0.636
CLV_NRD_NRD_1 535 537 PF00675 0.736
CLV_PCSK_KEX2_1 133 135 PF00082 0.678
CLV_PCSK_KEX2_1 173 175 PF00082 0.680
CLV_PCSK_KEX2_1 330 332 PF00082 0.720
CLV_PCSK_KEX2_1 352 354 PF00082 0.740
CLV_PCSK_KEX2_1 36 38 PF00082 0.743
CLV_PCSK_KEX2_1 382 384 PF00082 0.822
CLV_PCSK_KEX2_1 450 452 PF00082 0.574
CLV_PCSK_KEX2_1 495 497 PF00082 0.636
CLV_PCSK_KEX2_1 53 55 PF00082 0.565
CLV_PCSK_KEX2_1 535 537 PF00082 0.736
CLV_PCSK_PC1ET2_1 36 38 PF00082 0.743
CLV_PCSK_PC1ET2_1 53 55 PF00082 0.565
CLV_PCSK_PC7_1 326 332 PF00082 0.728
CLV_PCSK_SKI1_1 24 28 PF00082 0.736
CLV_PCSK_SKI1_1 495 499 PF00082 0.583
CLV_PCSK_SKI1_1 535 539 PF00082 0.734
CLV_Separin_Metazoa 265 269 PF03568 0.776
CLV_Separin_Metazoa 308 312 PF03568 0.706
DEG_APCC_DBOX_1 359 367 PF00400 0.813
DEG_Nend_UBRbox_1 1 4 PF02207 0.661
DEG_SCF_FBW7_1 94 101 PF00400 0.832
DEG_SPOP_SBC_1 248 252 PF00917 0.783
DEG_SPOP_SBC_1 459 463 PF00917 0.662
DOC_MAPK_gen_1 21 30 PF00069 0.739
DOC_PP4_MxPP_1 264 267 PF00568 0.779
DOC_USP7_MATH_1 22 26 PF00917 0.666
DOC_USP7_MATH_1 248 252 PF00917 0.791
DOC_USP7_MATH_1 270 274 PF00917 0.811
DOC_USP7_MATH_1 275 279 PF00917 0.765
DOC_USP7_MATH_1 284 288 PF00917 0.655
DOC_USP7_MATH_1 358 362 PF00917 0.595
DOC_USP7_MATH_1 408 412 PF00917 0.816
DOC_USP7_MATH_1 45 49 PF00917 0.733
DOC_USP7_MATH_1 459 463 PF00917 0.777
DOC_USP7_MATH_1 471 475 PF00917 0.574
DOC_USP7_MATH_1 70 74 PF00917 0.648
DOC_USP7_MATH_1 98 102 PF00917 0.795
DOC_USP7_UBL2_3 12 16 PF12436 0.713
DOC_USP7_UBL2_3 65 69 PF12436 0.840
DOC_WW_Pin1_4 105 110 PF00397 0.643
DOC_WW_Pin1_4 117 122 PF00397 0.657
DOC_WW_Pin1_4 160 165 PF00397 0.660
DOC_WW_Pin1_4 204 209 PF00397 0.741
DOC_WW_Pin1_4 214 219 PF00397 0.583
DOC_WW_Pin1_4 234 239 PF00397 0.594
DOC_WW_Pin1_4 252 257 PF00397 0.541
DOC_WW_Pin1_4 280 285 PF00397 0.764
DOC_WW_Pin1_4 296 301 PF00397 0.635
DOC_WW_Pin1_4 353 358 PF00397 0.789
DOC_WW_Pin1_4 455 460 PF00397 0.733
DOC_WW_Pin1_4 461 466 PF00397 0.762
DOC_WW_Pin1_4 512 517 PF00397 0.671
DOC_WW_Pin1_4 82 87 PF00397 0.732
DOC_WW_Pin1_4 94 99 PF00397 0.646
LIG_14-3-3_CanoR_1 21 30 PF00244 0.661
LIG_14-3-3_CanoR_1 210 219 PF00244 0.661
LIG_14-3-3_CanoR_1 246 256 PF00244 0.751
LIG_14-3-3_CanoR_1 271 279 PF00244 0.751
LIG_14-3-3_CanoR_1 315 319 PF00244 0.621
LIG_14-3-3_CanoR_1 360 364 PF00244 0.603
LIG_BRCT_BRCA1_1 363 367 PF00533 0.787
LIG_BRCT_BRCA1_1 368 372 PF00533 0.738
LIG_CSL_BTD_1 109 112 PF09270 0.821
LIG_CSL_BTD_1 215 218 PF09270 0.705
LIG_deltaCOP1_diTrp_1 107 114 PF00928 0.752
LIG_FHA_1 485 491 PF00498 0.594
LIG_FHA_2 143 149 PF00498 0.633
LIG_FHA_2 177 183 PF00498 0.680
LIG_FHA_2 340 346 PF00498 0.717
LIG_LIR_Apic_2 217 222 PF02991 0.689
LIG_LIR_Nem_3 107 113 PF02991 0.823
LIG_LIR_Nem_3 147 153 PF02991 0.827
LIG_MLH1_MIPbox_1 368 372 PF16413 0.805
LIG_NRP_CendR_1 560 562 PF00754 0.604
LIG_Pex14_1 110 114 PF04695 0.833
LIG_Pex14_2 239 243 PF04695 0.691
LIG_Pex14_2 367 371 PF04695 0.804
LIG_REV1ctd_RIR_1 369 375 PF16727 0.803
LIG_SH2_NCK_1 387 391 PF00017 0.754
LIG_SH2_SRC 4 7 PF00017 0.722
LIG_SH2_STAP1 176 180 PF00017 0.679
LIG_SH2_STAP1 334 338 PF00017 0.753
LIG_SH2_STAP1 387 391 PF00017 0.754
LIG_SH2_STAT5 4 7 PF00017 0.722
LIG_SH2_STAT5 547 550 PF00017 0.606
LIG_SH3_1 294 300 PF00018 0.651
LIG_SH3_2 297 302 PF14604 0.727
LIG_SH3_3 106 112 PF00018 0.825
LIG_SH3_3 215 221 PF00018 0.767
LIG_SH3_3 264 270 PF00018 0.778
LIG_SH3_3 294 300 PF00018 0.826
LIG_SH3_3 313 319 PF00018 0.504
LIG_SH3_3 351 357 PF00018 0.688
LIG_SH3_3 71 77 PF00018 0.790
LIG_SH3_4 12 19 PF00018 0.715
LIG_SH3_5 423 427 PF00018 0.730
LIG_SUMO_SIM_anti_2 25 31 PF11976 0.646
LIG_SUMO_SIM_par_1 25 31 PF11976 0.646
LIG_TRAF2_1 135 138 PF00917 0.774
LIG_TRAF2_1 145 148 PF00917 0.619
LIG_TRAF2_1 31 34 PF00917 0.543
LIG_WW_3 265 269 PF00397 0.776
LIG_WW_3 308 312 PF00397 0.748
LIG_WW_3 76 80 PF00397 0.815
MOD_CDC14_SPxK_1 207 210 PF00782 0.816
MOD_CDC14_SPxK_1 299 302 PF00782 0.691
MOD_CDK_SPK_2 121 126 PF00069 0.784
MOD_CDK_SPxK_1 204 210 PF00069 0.825
MOD_CDK_SPxK_1 296 302 PF00069 0.688
MOD_CDK_SPxK_1 512 518 PF00069 0.675
MOD_CDK_SPxxK_3 353 360 PF00069 0.790
MOD_CK1_1 120 126 PF00069 0.764
MOD_CK1_1 206 212 PF00069 0.621
MOD_CK1_1 214 220 PF00069 0.597
MOD_CK1_1 249 255 PF00069 0.770
MOD_CK1_1 278 284 PF00069 0.848
MOD_CK1_1 333 339 PF00069 0.751
MOD_CK1_1 361 367 PF00069 0.682
MOD_CK1_1 407 413 PF00069 0.828
MOD_CK1_1 415 421 PF00069 0.682
MOD_CK1_1 458 464 PF00069 0.800
MOD_CK1_1 474 480 PF00069 0.491
MOD_CK2_1 133 139 PF00069 0.773
MOD_CK2_1 142 148 PF00069 0.633
MOD_CK2_1 193 199 PF00069 0.852
MOD_CK2_1 259 265 PF00069 0.866
MOD_CK2_1 28 34 PF00069 0.622
MOD_CK2_1 408 414 PF00069 0.643
MOD_CMANNOS 216 219 PF00535 0.817
MOD_DYRK1A_RPxSP_1 353 357 PF00069 0.788
MOD_DYRK1A_RPxSP_1 84 88 PF00069 0.829
MOD_GlcNHglycan 115 118 PF01048 0.774
MOD_GlcNHglycan 195 198 PF01048 0.851
MOD_GlcNHglycan 213 216 PF01048 0.491
MOD_GlcNHglycan 24 27 PF01048 0.661
MOD_GlcNHglycan 272 275 PF01048 0.818
MOD_GlcNHglycan 280 283 PF01048 0.741
MOD_GlcNHglycan 316 319 PF01048 0.756
MOD_GlcNHglycan 336 339 PF01048 0.751
MOD_GlcNHglycan 368 371 PF01048 0.805
MOD_GlcNHglycan 406 409 PF01048 0.840
MOD_GlcNHglycan 476 479 PF01048 0.560
MOD_GlcNHglycan 49 52 PF01048 0.697
MOD_GlcNHglycan 505 508 PF01048 0.732
MOD_GSK3_1 113 120 PF00069 0.537
MOD_GSK3_1 133 140 PF00069 0.617
MOD_GSK3_1 230 237 PF00069 0.771
MOD_GSK3_1 247 254 PF00069 0.545
MOD_GSK3_1 278 285 PF00069 0.814
MOD_GSK3_1 330 337 PF00069 0.754
MOD_GSK3_1 358 365 PF00069 0.783
MOD_GSK3_1 366 373 PF00069 0.707
MOD_GSK3_1 404 411 PF00069 0.821
MOD_GSK3_1 412 419 PF00069 0.714
MOD_GSK3_1 454 461 PF00069 0.775
MOD_GSK3_1 94 101 PF00069 0.832
MOD_LATS_1 328 334 PF00433 0.759
MOD_N-GLC_1 433 438 PF02516 0.586
MOD_N-GLC_2 433 435 PF02516 0.625
MOD_NEK2_1 113 118 PF00069 0.771
MOD_NEK2_1 28 33 PF00069 0.720
MOD_NEK2_1 366 371 PF00069 0.761
MOD_NEK2_1 40 45 PF00069 0.583
MOD_NEK2_1 412 417 PF00069 0.712
MOD_NEK2_1 503 508 PF00069 0.592
MOD_NEK2_1 511 516 PF00069 0.607
MOD_PIKK_1 115 121 PF00454 0.775
MOD_PIKK_1 347 353 PF00454 0.671
MOD_PIKK_1 40 46 PF00454 0.708
MOD_PIKK_1 412 418 PF00454 0.775
MOD_PKA_1 133 139 PF00069 0.678
MOD_PKA_1 330 336 PF00069 0.716
MOD_PKA_2 133 139 PF00069 0.843
MOD_PKA_2 20 26 PF00069 0.757
MOD_PKA_2 270 276 PF00069 0.848
MOD_PKA_2 314 320 PF00069 0.621
MOD_PKA_2 330 336 PF00069 0.599
MOD_PKA_2 359 365 PF00069 0.817
MOD_PKA_2 385 391 PF00069 0.830
MOD_PKA_2 491 497 PF00069 0.590
MOD_PKB_1 244 252 PF00069 0.745
MOD_Plk_1 433 439 PF00069 0.583
MOD_Plk_1 484 490 PF00069 0.617
MOD_Plk_4 362 368 PF00069 0.649
MOD_ProDKin_1 105 111 PF00069 0.645
MOD_ProDKin_1 117 123 PF00069 0.659
MOD_ProDKin_1 160 166 PF00069 0.661
MOD_ProDKin_1 204 210 PF00069 0.740
MOD_ProDKin_1 214 220 PF00069 0.582
MOD_ProDKin_1 234 240 PF00069 0.593
MOD_ProDKin_1 252 258 PF00069 0.541
MOD_ProDKin_1 280 286 PF00069 0.764
MOD_ProDKin_1 296 302 PF00069 0.638
MOD_ProDKin_1 353 359 PF00069 0.789
MOD_ProDKin_1 455 461 PF00069 0.736
MOD_ProDKin_1 512 518 PF00069 0.675
MOD_ProDKin_1 82 88 PF00069 0.729
MOD_ProDKin_1 94 100 PF00069 0.646
MOD_SUMO_rev_2 461 471 PF00179 0.731
TRG_DiLeu_BaEn_3 147 153 PF01217 0.614
TRG_DiLeu_BaLyEn_6 476 481 PF01217 0.671
TRG_ENDOCYTIC_2 149 152 PF00928 0.614
TRG_ER_diArg_1 173 175 PF00400 0.684
TRG_ER_diArg_1 243 246 PF00400 0.744
TRG_ER_diArg_1 352 354 PF00400 0.740
TRG_ER_diArg_1 427 430 PF00400 0.723
TRG_ER_diArg_1 450 452 PF00400 0.709
TRG_ER_diArg_1 534 536 PF00400 0.740
TRG_Pf-PMV_PEXEL_1 155 160 PF00026 0.631
TRG_Pf-PMV_PEXEL_1 38 42 PF00026 0.682
TRG_Pf-PMV_PEXEL_1 438 442 PF00026 0.706
TRG_Pf-PMV_PEXEL_1 450 454 PF00026 0.524
TRG_Pf-PMV_PEXEL_1 496 500 PF00026 0.716
TRG_Pf-PMV_PEXEL_1 536 540 PF00026 0.728

Homologs

Protein Taxonomy Sequence identity Coverage
A4H9H3 Leishmania braziliensis 61% 100%
A4HXT9 Leishmania infantum 99% 100%
E9ARK1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
Q4QDX8 Leishmania major 88% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS