LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

NADH-ubiquinone_oxidoreductase_complex_I_subunit_ putative/GeneDB:LmjF.18.1480

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
NADH-ubiquinone_oxidoreductase_complex_I_subunit_ putative/GeneDB:LmjF.18.1480
Gene product:
NADH-ubiquinone oxidoreductase complex I subunit, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WV29_LEIDO
TriTrypDb:
LdBPK_181460.1 , LdCL_180020000 , LDHU3_18.1860
Length:
258

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005739 mitochondrion 5 1
GO:0016020 membrane 2 12
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 12
Previous1Next

Expansion

Sequence features

A0A3S7WV29
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WV29

Function

Biological processes
TermNameLevelCount
GO:0006091 generation of precursor metabolites and energy 3 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0022900 electron transport chain 4 12
GO:0022904 respiratory electron transport chain 5 12
GO:0042773 ATP synthesis coupled electron transport 6 12
GO:0044237 cellular metabolic process 2 12
Previous1Next
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 12
GO:0003954 NADH dehydrogenase activity 4 12
GO:0003955 NAD(P)H dehydrogenase (quinone) activity 5 12
GO:0005215 transporter activity 1 12
GO:0005488 binding 1 12
GO:0008137 NADH dehydrogenase (ubiquinone) activity 4 12
GO:0009055 electron transfer activity 3 12
GO:0015399 primary active transmembrane transporter activity 4 12
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5 12
GO:0016491 oxidoreductase activity 2 12
Previous12Next

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_KEX2_1 41 43 PF00082 0.228
CLV_PCSK_PC1ET2_1 41 43 PF00082 0.228
CLV_PCSK_SKI1_1 174 178 PF00082 0.290
DEG_APCC_DBOX_1 203 211 PF00400 0.332
DOC_MAPK_gen_1 114 123 PF00069 0.228
DOC_MAPK_gen_1 32 39 PF00069 0.331
DOC_MAPK_MEF2A_6 117 125 PF00069 0.228
DOC_MAPK_MEF2A_6 66 75 PF00069 0.228
DOC_PP1_RVXF_1 183 190 PF00149 0.273
DOC_PP1_RVXF_1 32 39 PF00149 0.388
Previous123456Next

Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PD86 Leptomonas seymouri 96% 82%
A0A0S4JNM7 Bodo saltans 85% 82%
A0A1X0P7Y8 Trypanosomatidae 86% 87%
A0A422NIN5 Trypanosoma rangeli 82% 87%
A4H9Q2 Leishmania braziliensis 96% 100%
A4HY18 Leishmania infantum 100% 100%
D0A567 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 86% 85%
E9ART2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
P22318 Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) 29% 100%
Q4QDP1 Leishmania major 99% 100%
Previous12Next

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS